The synthesis of amino-acid functionalized β-Carbolines as topoisomerase II inhibitors von Deveau, Amy Morin, Labroli, Marc A, Dieckhaus, Christine M, Barthen, Mary T, Smith, Kirsten S, Macdonald, Timothy L

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Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase von BOGER, D. L, LABROLI, M. A, MARSILJE, A. T. H, QING JIN, HEDRICK, M. P, BAKER, S. J, JAE HOON SHIM, BENKOVIC, S. J

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The synthesis and evaluation of benzannelated-azatoxins: The benzazatoxins von Miller, Thomas A., Vachaspati, Prakash R., Labroli, Marc A., Thompson, Charles D., Bulman, Amanda L., Macdonald, Timothy L.

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Total Syntheses of Ningalin A, Lamellarin O, Lukianol A, and Permethyl Storniamide A Utilizing Heterocyclic Azadiene Diels−Alder Reactions von Boger, Dale L, Boyce, Christopher W, Labroli, Marc A, Sehon, Clark A, Jin, Qing

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Piperazine-Based CCR5 Antagonists as HIV-1 Inhibitors. IV. Discovery of 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-{2-methoxy-1(R)-4-(trifluoromethyl)phenyl}ethyl-3(S)-methyl-1... von Tagat, Jayaram R, McCombie, Stuart W, Nazareno, Dennis, Labroli, Marc A, Xiao, Yushi, Steensma, Ruo W, Strizki, Julie M, Baroudy, Bahige M, Cox, Kathleen, Lachowicz, Jean, Varty, Geoffrey, Watkins, Robert

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10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-ddacthf) : A potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine... von MARSILJE, Thomas H, LABROLI, Marc A, WILSON, Ian A, BEARDSLEY, G. Peter, BENKOVIC, Stephen J, BOGER, Dale L, HEDRICK, Michael P, QING JIN, DESHARNAIS, Joel, BAKER, Stephen J, GOOLJARSINGH, Lata T, RAMCHARAN, Joseph, TAVASSOLI, Ali, YAN ZHANG

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USO DE COMPUESTO DERIVADOS DE PIRAZOLOPIRIMIDINAS, INHIBIDORES DE QUINASAS DEPENDIENTES DE CICLINAS PARA INHIBIR EL CRECIMIENTO DE UN TUMOR von GUZI TIMOTHY J., PARUCH KAMIL, DWYER MICHAEL P., LABROLI MARC A., KEERTIKAR KARTIK M

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Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase von Walker, Scott S, Labroli, Marc, Painter, Ronald E, Wiltsie, Judyann, Sherborne, Brad, Murgolo, Nicholas, Sher, Xinwei, Mann, Paul, Zuck, Paul, Garlisi, Charles G, Su, Jing, Kargman, Stacia, Xiao, Li, Scapin, Giovanna, Salowe, Scott, Devito, Kristine, Sheth, Payal, Buist, Nichole, Tan, Christopher M, Black, Todd A, Roemer, Terry

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A convergent preparation of the CHK1 inhibitor MK-8776 (SCH 900776) von Labroli, Marc A., Dwyer, Michael P., Poker, Cory, Keertikar, Kerry M., Rossman, Randall, Guzi, Timothy J.

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Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 1 von Dwyer, Michael P., Paruch, Kamil, Labroli, Marc, Alvarez, Carmen, Keertikar, Kerry M., Poker, Cory, Rossman, Randall, Fischmann, Thierry O., Duca, Jose S., Madison, Vincent, Parry, David, Davis, Nicole, Seghezzi, Wolfgang, Wiswell, Derek, Guzi, Timothy J.

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Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy von Skudlarek, Jason W, Cooke, Andrew J, Mitchell, Helen J, Babaoglu, Kerim, Shaw, Anthony W, Tong, Ling, Nomland, Ashley B, Labroli, Marc, Sha, Deyou, Mulhearn, James J, Wu, Chengwei, Li, Sarah W, Beshore, Douglas C, Hughes, Jonathan M E, Jouffroy, Matthieu, Wang, Hao, Balibar, Carl J, Painter, Ronald E, Shen, Pamela, Lange, Henry S, Ishchenko, Andrii, Chen, Yun-Ting, Klein, Daniel J, Tracy, Rodger W, Miller, Randy R, Cabalu, Tamara D, Wu, Zhe, Leithead, Andrew, Scapin, Giovanna, Hruza, Alan W, Dzhekieva, Liudmila, Bukhtiyarova, Marina, Homsher, Michelle F, Xu, Min, Bahnck-Teets, Carolyn, McKenney, David, Buevich, Alexei V, Liu, Jian, Zhang, Li-Kang, Meng, Tao, Kelly, Terri, DiNunzio, Edward, Soisson, Stephen, Cheng, Robert K Y, Hennig, Michael, Raheem, Izzat, Walker, Scott S

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Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles von Sanders, John M, Beshore, Douglas C, Culberson, J Christopher, Fells, James I, Imbriglio, Jason E, Gunaydin, Hakan, Haidle, Andrew M, Labroli, Marc, Mattioni, Brian E, Sciammetta, Nunzio, Shipe, William D, Sheridan, Robert P, Suen, Linda M, Verras, Andreas, Walji, Abbas, Joshi, Elizabeth M, Bueters, Tjerk

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Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships von Plotkin, Michael A., Labroli, Marc, Schubert, Jeffrey, Shaw, Anthony, Schlegel, Kelly-Ann S., Berger, Richard, Cooke, Andrew J., Hayes, Robert P., Armacost, Kira A., Kinek, Keith, Krosky, Paula, Burlein, Christine, Meng, Shi, DiNunzio, Edward, Murray, Edward M., Agrawal, Sony, Madeira, Maria, Flattery, Amy, Yao, Huifang, Leithead, Andrew, Rose, William A, Cox, Christopher, Tellers, David M., McKenna, Philip M., Raheem, Izzat

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Quantitation of wall teichoic acid in Staphylococcus aureus by direct measurement of monomeric units using LC-MS/MS von Berejnaia, Olga, Wang, Hao, Labroli, Marc, Yang, Christine, Gill, Charles, Xiao, Jianying, Hesk, David, DeJesus, Reynalda, Su, Jing, Tan, Christopher M., Sheth, Payal R., Kavana, Michael, McLaren, David G.

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Benzimidazole analogs as WTA biosynthesis inhibitors targeting methicillin resistant Staphylococcus aureus von Yang, Shu-Wei, Pan, Jianping, Yang, Christine, Labroli, Marc, Pan, Weidong, Caldwell, John, Ha, Sookhee, Koseoglu, Sandra, Xiao, Jing C., Mayhood, Todd, Sheth, Payal R., Garlisi, Charles G., Wu, Jin, Lee, Sang Ho, Wang, Hao, Tan, Christopher M., Roemer, Terry, Su, Jing

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Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles: Miniperspective von Sanders, John M, Beshore, Douglas C, Culberson, J. Christopher, Fells, James I, Imbriglio, Jason E, Gunaydin, Hakan, Haidle, Andrew M, Labroli, Marc, Mattioni, Brian E, Sciammetta, Nunzio, Shipe, William D, Sheridan, Robert P, Suen, Linda M, Verras, Andreas, Walji, Abbas, Joshi, Elizabeth M, Bueters, Tjerk

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Murgocil is a Highly Bioactive Staphylococcal-Specific Inhibitor of the Peptidoglycan Glycosyltransferase Enzyme MurG von Mann, Paul A, Müller, Anna, Xiao, Li, Pereira, Pedro M, Yang, Christine, Ho Lee, Sang, Wang, Hao, Trzeciak, Joanna, Schneeweis, Jonathan, dos Santos, Margarida Moreira, Murgolo, Nicholas, She, Xinwei, Gill, Charles, Balibar, Carl J, Labroli, Marc, Su, Jing, Flattery, Amy, Sherborne, Brad, Maier, Richard, Tan, Christopher M, Black, Todd, Önder, Kamil, Kargman, Stacia, Monsma, Frederick J, Pinho, Mariana G, Schneider, Tanja, Roemer, Terry

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NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA von Hou, Yan, Mayhood, Todd, Sheth, Payal, Tan, Christopher M., Labroli, Marc, Su, Jing, Wyss, Daniel F., Roemer, Terry, McCoy, Mark A.

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PYRAZOLOPYRIMIDINE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF HERPESVIRUSES von LABROLI, Marc, A, ARMACOST, Kira, A, CROWLEY, Brendan, M, COOKE, Andrew, J, SCHLEGEL, Kelly-Ann S, SHAW, Anthony, W, COX, Christopher Douglas, PLOTKIN, Michael, A, RAHEEM, Izzat, T

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BICYCLIC HETEROCYCLE COMPOUNDS METHODS OF USE THEREOF FOR THE TREATMENT OF HERPES VIRUSES von TONG, Ling, RAHEEM, Izzat Tiedje, COOKE, Andrew John, LABROLI, Marc, A, PLOTKIN, Michael Aaron, CROWLEY, Brendan, M, SHA, Deyou

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