Mechanism of parkin activation by phosphorylation von Sauvé, Véronique, Sung, George, Soya, Naoto, Kozlov, Guennadi, Blaimschein, Nina, Miotto, Lis Schwartz, Trempe, Jean-François, Lukacs, Gergely L., Gehring, Kalle

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PINK1 autophosphorylation is required for ubiquitin recognition von Rasool, Shafqat, Soya, Naoto, Truong, Luc, Croteau, Nathalie, Lukacs, Gergely L, Trempe, Jean‐François

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From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations von Veit, Gudio, Avramescu, Radu G, Chiang, Annette N, Houck, Scott A, Cai, Zhiwei, Peters, Kathryn W, Hong, Jeong S, Pollard, Harvey B, Guggino, William B, Balch, William E, Skach, William R, Cutting, Garry R, Frizzell, Raymond A, Sheppard, David N, Cyr, Douglas M, Sorscher, Eric J, Brodsky, Jeffrey L, Lukacs, Gergely L

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Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination von Veit, Guido, Roldan, Ariel, Hancock, Mark A, Da Fonte, Dillon F, Xu, Haijin, Hussein, Maytham, Frenkiel, Saul, Matouk, Elias, Velkov, Tony, Lukacs, Gergely L

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Cooperative assembly and misfolding of CFTR domains in vivo von Du, Kai, Lukacs, Gergely L

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Correction of Both NBD1 Energetics and Domain Interface Is Required to Restore ΔF508 CFTR Folding and Function von Rabeh, Wael M., Bossard, Florian, Xu, Haijin, Okiyoneda, Tsukasa, Bagdany, Miklos, Mulvihill, Cory M., Du, Kai, di Bernardo, Salvatore, Liu, Yuhong, Konermann, Lars, Roldan, Ariel, Lukacs, Gergely L.

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Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane von Okiyoneda, Tsukasa, Barrière, Hervé, Bagdány, Miklós, Rabeh, Wael M, Du, Kai, Höhfeld, Jörg, Young, Jason C, Lukacs, Gergely L

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Alcohol Disrupts Levels and Function of the Cystic Fibrosis Transmembrane Conductance Regulator to Promote Development of Pancreatitis von Maléth, József, Balázs, Anita, Pallagi, Petra, Balla, Zsolt, Kui, Balázs, Katona, Máté, Judák, Linda, Németh, István, Kemény, Lajos V., Rakonczay, Zoltán, Venglovecz, Viktória, Földesi, Imre, Pető, Zoltán, Somorácz, Áron, Borka, Katalin, Perdomo, Doranda, Lukacs, Gergely L., Gray, Mike A., Monterisi, Stefania, Zaccolo, Manuela, Sendler, Matthias, Mayerle, Julia, Kühn, Jens-Peter, Lerch, Markus M., Sahin-Tóth, Miklós, Hegyi, Péter

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Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR von Baaklini, Imad, Gonçalves, Conrado de Campos, Lukacs, Gergely L., Young, Jason C.

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Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain–domain coupling von Soya, Naoto, Xu, Haijin, Roldan, Ariel, Yang, Zhengrong, Ye, Haoxin, Jiang, Fan, Premchandar, Aiswarya, Veit, Guido, Cole, Susan P. C., Kappes, John, Hegedüs, Tamás, Lukacs, Gergely L.

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Fixing cystic fibrosis by correcting CFTR domain assembly von Okiyoneda, Tsukasa, Lukacs, Gergely L

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Mutation-specific downregulation of CFTR2 variants by gating potentiators von Avramescu, Radu G, Kai, Yukari, Xu, Haijin, Bidaud-Meynard, Aurélien, Schnúr, Andrea, Frenkiel, Saul, Matouk, Elias, Veit, Guido, Lukacs, Gergely L

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Synergy-Based Small-Molecule Screen Using a Human Lung Epithelial Cell Line Yields ΔF508-CFTR Correctors That Augment VX-809 Maximal Efficacy von Phuan, Puay-Wah, Veit, Guido, Tan, Joseph, Roldan, Ariel, Finkbeiner, Walter E., L. Lukacs, Gergely, Verkman, A.S.

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Protein homeostasis at the plasma membrane von Apaja, Pirjo M, Lukacs, Gergely L

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Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell von Bagdany, Miklos, Veit, Guido, Fukuda, Ryosuke, Avramescu, Radu G., Okiyoneda, Tsukasa, Baaklini, Imad, Singh, Jay, Sovak, Guy, Xu, Haijin, Apaja, Pirjo M., Sattin, Sara, Beitel, Lenore K., Roldan, Ariel, Colombo, Giorgio, Balch, William, Young, Jason C., Lukacs, Gergely L.

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Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration von Kharitidi, Dmitri, Apaja, Pirjo M., Manteghi, Sanaz, Suzuki, Kei, Malitskaya, Elena, Roldan, Ariel, Gingras, Marie-Claude, Takagi, Junichi, Lukacs, Gergely L., Pause, Arnim

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Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations von Premchandar, Aiswarya, Ming, Ruiji, Baiad, Abed, Da Fonte, Dillon F, Xu, Haijin, Faubert, Denis, Veit, Guido, Lukacs, Gergely L

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Mutation-specific peripheral and ER quality control of hERG channel cell-surface expression von Foo, Brian, Barbier, Camille, Guo, Kevin, Vasantharuban, Jaminie, Lukacs, Gergely L., Shrier, Alvin

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Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia von Veit, Guido, Bossard, Florian, Goepp, Julie, Verkman, A S, Galietta, Luis J V, Hanrahan, John W, Lukacs, Gergely L

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Elexacaftor co-potentiates the activity of F508del and gating mutants of CFTR von Veit, Guido, Vaccarin, Christian, Lukacs, Gergely L.

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