Neoclassic Drug Discovery: The Case for Lead Generation Using Phenotypic and Functional Approaches von Lee, Jonathan A., Berg, Ellen L.

Volltext

Consideration of the cellular microenvironment: Physiologically relevant co-culture systems in drug discovery von L. Berg, Ellen, Hsu, Yu-Chih, Lee, Jonathan A.

Volltext

Phenotypic chemical biology for predicting safety and efficacy von Berg, Ellen L.

Volltext

The future of phenotypic drug discovery von Berg, Ellen L.

Volltext

Human Cell-Based in vitro Phenotypic Profiling for Drug Safety-Related Attrition von Berg, Ellen L

Volltext

Building Predictive Models for Mechanism-of-Action Classification from Phenotypic Assay Data Sets von Berg, Ellen L., Yang, Jian, Polokoff, Mark A.

Volltext

Systems biology in drug discovery and development von Berg, Ellen L.

Volltext

Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation von Melton, Andrew C, Melrose, Jennifer, Alajoki, Liisa, Privat, Sylvie, Cho, Hannah, Brown, Naomi, Plavec, Ana Marija, Nguyen, Dat, Johnston, Elijah D, Yang, Jian, Polokoff, Mark A, Plavec, Ivan, Berg, Ellen L, O'Mahony, Alison

Volltext

Bioassay protocol metadata annotation: Proposed standards adoption von Balakrishnan, Rama, Berg, Ellen L., Butler, Christopher C., Clark, Alex M., Denker, Sheryl P., Feierberg, Isabella, Harris, Jason, Ikeda, Timothy P., Jeschonek, Samantha, Makarov, Vladimir A., Southan, Christopher, Vanderwall, Dana, Winstanley, Peter

Volltext

Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes von Simms, Liam, Mason, Elizabeth, Berg, Ellen L., Yu, Fan, Rudd, Kathryn, Czekala, Lukasz, Trelles Sticken, Edgar, Brinster, Oleg, Wieczorek, Roman, Stevenson, Matthew, Walele, Tanvir

Volltext

The activities of drug inactive ingredients on biological targets von Pottel, Joshua, Armstrong, Duncan, Zou, Ling, Fekete, Alexander, Huang, Xi-Ping, Torosyan, Hayarpi, Bednarczyk, Dallas, Whitebread, Steven, Bhhatarai, Barun, Liang, Guiqing, Jin, Hong, Ghaemi, S Nassir, Slocum, Samuel, Lukacs, Katalin V, Irwin, John J, Berg, Ellen L, Giacomini, Kathleen M, Roth, Bryan L, Shoichet, Brian K, Urban, Laszlo

Volltext

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms von Kleinstreuer, Nicole C, Yang, Jian, Berg, Ellen L, Knudsen, Thomas B, Richard, Ann M, Martin, Matthew T, Reif, David M, Judson, Richard S, Polokoff, Mark, Dix, David J, Kavlock, Robert J, Houck, Keith A

Volltext

A Direct Comparison of Selectin-Mediated Transient, Adhesive Events Using High Temporal Resolution von Smith, McRae J., Berg, Ellen L., Lawrence, Michael B.

Volltext

Systems biology in drug discovery von Butcher, Eugene C, Berg, Ellen L, Kunkel, Eric J

Volltext

Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators von Shah, Falgun, Stepan, Antonia F., O'Mahony, Alison, Velichko, Sharlene, Folias, Alexandra E., Houle, Christopher, Shaffer, Christopher L., Marcek, John, Whritenour, Jessica, Stanton, Robert, Berg, Ellen L.

Volltext

Characterization of compound mechanisms and secondary activities by BioMAP analysis von Berg, Ellen L., Kunkel, Eric J., Hytopoulos, Evangelos, Plavec, Ivan

Volltext

An integrative biology approach for analysis of drug action in models of human vascular inflammation von Kunkel, Eric J., Dea, Marlene, Ebens, Allen, Hytopoulos, Evangelos, Melrose, Jennifer, Nguyen, Dat, Ota, Ken S., Plavec, Ivan, Wang, Yuker, Watson, Susan R., Butcher, Eugene C., Berg, Ellen L.

Volltext

Evaluation of 147 perfluoroalkyl substances for immunotoxic and other (patho)physiological activities through phenotypic screening of human primary cells von Houck, Keith A, Friedman, Katie Paul, Feshuk, Madison, Patlewicz, Grace, Smeltz, Marci, Clifton, M. Scott, Wetmore, Barbara A, Velichko, Sharlene, Berenyi, Antal, Berg, Ellen L

Volltext

Phenotypic profiling for understanding mechanisms of cardiovascular adverse reactions von Berg, Ellen L., Velichko, Sharlene, Nguyen, Dat T., Melrose, Jennifer, O'Mahony, Alison

Volltext

Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects von Berg, Ellen L, Polokoff, Mark A, O'Mahony, Alison, Nguyen, Dat, Li, Xitong

Volltext