Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins von Matzat, Leah H, Berberoglu, Stephen, Lévesque, Lyne

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Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes von Lévesque, Lyne, Mizzen, Craig A, McLachlan, Donald R, Fraser, Paul E

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NXT1 Is Necessary for the Terminal Step of Crm1-Mediated Nuclear Export von Black, Ben E., Holaska, James M., Lévesque, Lyne, Ossareh-Nazari, Batool, Gwizdek, Carol, Dargemont, Catherine, Paschal, Bryce M.

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Identification of an NTF2-Related Factor That Binds Ran-GTP and Regulates Nuclear Protein Export von Black, Ben E., Lévesque, Lyne, Holaska, James M., Wood, Todd C., Paschal, Bryce M.

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Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex von Lévesque, Lyne, Bor, Yeou-Cherng, Matzat, Leah H, Jin, Li, Berberoglu, Stephen, Rekosh, David, Hammarskjöld, Marie-Louise, Paschal, Bryce M

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RanGTP-Binding Protein NXT1 Facilitates Nuclear Export of Different Classes of RNA In Vitro von Ossareh-Nazari, B, Maison, C, Black, B E, Lévesque, L, Paschal, B M, Dargemont, C

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Phosphorylation, Subcellular Localization, and Membrane Orientation of the Alzheimer's Disease-associated Presenilins von De Strooper, Bart, Beullens, Monique, Contreras, Bart, Levesque, Lyne, Craessaerts, Katleen, Cordell, Barbara, Moechars, Dieder, Bollen, Mathieu, Fraser, Paul, St. George-Hyslop, Peter, Van Leuven, Fred

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NXT1 (p15) Is a Crucial Cellular Cofactor in TAP-Dependent Export of Intron-Containing RNA in Mammalian Cells von Guzik, Brian W., Levesque, Lyne, Prasad, Susan, Bor, Yeou-Cherng, Black, Ben E., Paschal, Bryce M., Rekosh, David, Hammarskjöld, Marie-Louise

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Evidence for Phosphorylation and Oligomeric Assembly of Presenilin 1 von Seeger, Mary, Nordstedt, Christer, Petanceska, Suzana, Kovacs, Dora M., Gouras, Gunnar K., Hahne, Solveig, Fraser, Paul, Levesque, Lyne, Czernik, Andrew J., St George-Hyslop, Peter, Sisodia, Sangram S., Thinakaran, Gopal, Tanzi, Rudolph E., Greengard, Paul, Gandy, Sam

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Presenilin structure, function and role in Alzheimer disease von Fraser, Paul E., Yang, Dun-Sheng, Yu, Gang, Lévesque, Lyne, Nishimura, Masaki, Arawaka, Shigeki, Serpell, Louise C., Rogaeva, Ekaterina, St George-Hyslop, Peter

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RNA Export Mediated by Tap Involves NXT1-dependent Interactions with the Nuclear Pore Complex von Lévesque, L, Guzik, B, Guan, T, Coyle, J, Black, B E, Rekosh, D, Hammarskjöld, M L, Paschal, B M

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing von Yu, Gang, Nishimura, Masaki, Arawaka, Shigeki, Levitan, Diane, Zhang, Lili, Tandon, Anurag, Song, You-Qiang, Rogaeva, Ekaterina, Chen, Fusheng, Kawarai, Toshitaka, Supala, Agnes, Levesque, Lyne, Yu, Haung, Yang, Dun-Sheng, Holmes, Erin, Milman, Paul, Liang, Yan, Zhang, Dong Mei, Xu, Dong Hong, Sato, Christine, Rogaev, Evgeny, Smith, Marsha, Janus, Christopher, Zhang, Yanni, Aebersold, Ruedi, Farrer, Lindsay, Sorbi, Sandro, Bruni, Amalia, Fraser, Paul, St George-Hyslop, Peter

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The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin von Yu, G, Chen, F, Levesque, G, Nishimura, M, Zhang, D M, Levesque, L, Rogaeva, E, Xu, D, Liang, Y, Duthie, M, St George-Hyslop, P H, Fraser, P E

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Presenilin 1 Controls γ-Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons von Annaert, Wim G., Levesque, Lyne, Craessaerts, Kathleen, Dierinck, Inge, Snellings, Greet, Westaway, David, St. George-Hyslop, Peter, Cordell, Barbara, Fraser, Paul, de Strooper, Bart

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Facioscapulohumeral Muscular Dystrophy Region Gene 1 Is a Dynamic RNA-Associated and Actin-Bundling Protein von Sun, Chia-Yun Jessica, van Koningsbruggen, Silvana, Long, Steven W., Straasheijm, Kirsten, Klooster, Rinse, Jones, Takako I., Bellini, Michel, Levesque, Lyne, Brieher, William M., van der Maarel, Silvère M., Jones, Peter L.

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Resolution of allelic and non-allelic variants of histone H1 by cation-exchange-hydrophilic-interaction chromatography von Mizzen, Craig A, Alpert, Andrew J, Lévesque, Lyne, Kruck, Theo.P.A, McLachlan, Donald R

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Glial expression of presenilin epitopes in human brain with cerebral infarction and in astrocytoma von MIAKE, H, TSUCHIYA, K, NAKAMURA, A, IKEDA, K, LEVESQUE, L, FRASER, P. E, HYSLOP, P. H. S.-G, MIZUSAWA, H, UCHIHARA, T

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Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease von Mathews, P M, Cataldo, A M, Kao, B H, Rudnicki, A G, Qin, X, Yang, J L, Jiang, Y, Picciano, M, Hulette, C, Lippa, C F, Bird, T D, Nochlin, D, Walter, J, Haass, C, Lévesque, L, Fraser, P E, Andreadis, A, Nixon, R A

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Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1 von Lévesque, L, Annaert, W, Craessaerts, K, Mathews, P M, Seeger, M, Nixon, R A, Van Leuven, F, Gandy, S, Westaway, D, St George-Hyslop, P, De Strooper, B, Fraser, P E

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Carboxyl-terminal Fragments of Alzheimer β-Amyloid Precursor Protein Accumulate in Restricted and Unpredicted Intracellular Compartments in Presenilin 1-deficient Cells von Chen, Fusheng, Yang, Dun-Sheng, Petanceska, Suzana, Yang, Austin, Tandon, Anurag, Yu, Gang, Rozmahel, Richard, Ghiso, Jorge, Nishimura, Masaki, Zhang, Dong Mei, Kawarai, Toshitaka, Levesque, Georges, Mills, Julia, Levesque, Lyne, Song, You-Qiang, Rogaeva, Ekaterina, Westaway, David, Mount, Howard, Gandy, Sam, St George-Hyslop, Peter, Fraser, Paul E.

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