Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells von Högström, Jenny, Heino, Sarika, Kallio, Pauliina, Lähde, Marianne, Leppänen, Veli-Matti, Balboa, Diego, Wiener, Zoltán, Alitalo, Kari

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Expression of R-Spondin 1 in Apc Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling von Lähde, Marianne, Heino, Sarika, Högström, Jenny, Kaijalainen, Seppo, Anisimov, Andrey, Flanagan, Dustin, Kallio, Pauliina, Leppänen, Veli-Matti, Ristimäki, Ari, Ritvos, Olli, Wu, Katherine, Tammela, Tuomas, Hodder, Michael, Sansom, Owen J., Alitalo, Kari

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Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling von Lähde, Marianne, Heino, Sarika, Högström, Jenny, Kaijalainen, Seppo, Anisimov, Andrey, Flanagan, Dustin, Kallio, Pauliina, Leppänen, Veli-Matti, Ristimäki, Ari, Ritvos, Olli, Wu, Katherine, Tammela, Tuomas, Hodder, Michael, Sansom, Owen J., Alitalo, Kari

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Blocking angiopoietin-2 promotes vascular damage and growth inhibition in mouse tumors treated with small doses of radiation von Kallio, Pauliina, Jokinen, Elina, Högström, Jenny, Das, Suvendu, Heino, Sarika, Lähde, Marianne, Brodkin, Jefim, Korhonen, Emilia A, Alitalo, Kari

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Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas von Heino, Sarika, Fang, Shentong, Lähde, Marianne, Högström, Jenny, Nassiri, Sina, Campbell, Andrew, Flanagan, Dustin, Raven, Alexander, Hodder, Michael, Nasreddin, Nadia, Xue, Hai-Hui, Delorenzi, Mauro, Leedham, Simon, Petrova, Tatiana V, Sansom, Owen, Alitalo, Kari

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NOTUM from Apc-mutant cells biases clonal competition to initiate cancer von Flanagan, Dustin J., Pentinmikko, Nalle, Luopajärvi, Kalle, Willis, Nicky J., Gilroy, Kathryn, Raven, Alexander P., Mcgarry, Lynn, Englund, Johanna I., Webb, Anna T., Scharaw, Sandra, Nasreddin, Nadia, Hodder, Michael C., Ridgway, Rachel A., Minnee, Emma, Sphyris, Nathalie, Gilchrist, Ella, Najumudeen, Arafath K., Romagnolo, Beatrice, Perret, Christine, Williams, Ann C., Clevers, Hans, Nummela, Pirjo, Lähde, Marianne, Alitalo, Kari, Hietakangas, Ville, Hedley, Ann, Clark, William, Nixon, Colin, Kirschner, Kristina, Jones, E. Yvonne, Ristimäki, Ari, Leedham, Simon J., Fish, Paul V., Vincent, Jean-Paul, Katajisto, Pekka, Sansom, Owen J.

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Abstract 861: Angiopoietin-2 blocking antibodies improve tumor growth inhibition and survival in mice treated with low doses of radiation von Kallio, Pauliina, Jokinen, Elina, Das, Suvendu, Högström, Jenny, Heino, Sarika, Lähde, Marianne, Alitalo, Kari

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Abstract LB-094: Systemic RSPO1 delivery leads to regression of intestinal adenomas via activation of the TGFβ/SMAD pathway von Lähde, Marianne, Heino, Sarika, Högström, Jenny, Leppänen, Veli-Matti, Kaijalainen, Seppo, Ritvos, Olli, Sansom, Owen, Alitalo, Kari

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Abstract 1143: Prox1 and Notch mark distinct colorectal cancer stem cell populations von Högström, Jenny, Heino, Sarika, Kallio, Pauliina, Lähde, Marianne, Leppänen, Veli-Matti, Kaijalainen, Seppo, Balboa, Diego, Otonkoski, Timo, Robine, Sylvie, Wiener, Zoltan, Alitalo, Kari

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Apc-mutant cells deploy Notum to bias clonal competition and drive cancer von Flanagan, Dustin J., Pentinmikko, Nalle, Luopajärvi, Kalle, Willis, Nicky J., Gilroy, Kathryn, Raven, Alexander P., Mcgarry, Lynn, Englund, Johanna I., Webb, Anna, Scharaw, Sandra, Nasreddin, Nadia, Hodder, Michael C., Ridgway, Rachel A., Minnee, Emma, Sphyris, Nathalie, Gilchrist, Ella, Najumudeen, Arafath K., Romagnolo, Beatrice, Perret, Christine, Williams, Ann C., Clevers, Hans, Nummela, Pirjo, Lähde, Marianne, Alitalo, Kari, Hietakangas, Ville, Hedley, Ann, Clark, William, Nixon, Colin, Kirschner, Kristina, Yvonne Jones, E., Ristimäki, Ari, Leedham, Simon, Fish, Paul V., Vincent, Jean-Paul, Katajisto, Pekka, Sansom, Owen J.

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Expression of R-Spondin 1 in Apc Min/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling von Lähde, Marianne, Heino, Sarika, Högström, Jenny, Kaijalainen, Seppo, Anisimov, Andrey, Flanagan, Dustin, Kallio, Pauliina, Leppänen, Veli-Matti, Ristimäki, Ari, Ritvos, Olli, Wu, Katherine, Tammela, Tuomas, Hodder, Michael, Sansom, Owen J, Alitalo, Kari

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