Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation von Lázaro, Diana F, Rodrigues, Eva F, Langohr, Ramona, Shahpasandzadeh, Hedieh, Ribeiro, Thales, Guerreiro, Patrícia, Gerhardt, Ellen, Kröhnert, Katharina, Klucken, Jochen, Pereira, Marcos D, Popova, Blagovesta, Kruse, Niels, Mollenhauer, Brit, Rizzoli, Silvio O, Braus, Gerhard H, Danzer, Karin M, Outeiro, Tiago F

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The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease von de Oliveira, Rita Machado, Vicente Miranda, Hugo, Francelle, Laetitia, Pinho, Raquel, Szegö, Éva M, Martinho, Renato, Munari, Francesca, Lázaro, Diana F, Moniot, Sébastien, Guerreiro, Patrícia, Fonseca-Ornelas, Luis, Marijanovic, Zrinka, Antas, Pedro, Gerhardt, Ellen, Enguita, Francisco Javier, Fauvet, Bruno, Penque, Deborah, Pais, Teresa Faria, Tong, Qiang, Becker, Stefan, Kügler, Sebastian, Lashuel, Hilal Ahmed, Steegborn, Clemens, Zweckstetter, Markus, Outeiro, Tiago Fleming

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Synucleinopathies: Where we are and where we need to go von Brás, Inês Caldeira, Dominguez‐Meijide, Antonio, Gerhardt, Ellen, Koss, David, Lázaro, Diana F., Santos, Patrícia I., Vasili, Eftychia, Xylaki, Mary, Outeiro, Tiago Fleming

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Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons von Pujols, Jordi, Peña-Díaz, Samuel, Lázaro, Diana F., Peccati, Francesca, Pinheiro, Francisca, González, Danilo, Carija, Anita, Navarro, Susanna, Conde-Giménez, María, García, Jesús, Guardiola, Salvador, Giralt, Ernest, Salvatella, Xavier, Sancho, Javier, Sodupe, Mariona, Outeiro, Tiago Fleming, Dalfó, Esther, Ventura, Salvador

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Cellular models as tools for the study of the role of alpha-synuclein in Parkinson's disease von Lázaro, Diana F., Pavlou, Maria Angeliki S., Outeiro, Tiago Fleming

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DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization von Popova, Blagovesta, Wang, Dan, Pätz, Christina, Akkermann, Dagmar, Lázaro, Diana F, Galka, Dajana, Kolog Gulko, Miriam, Bohnsack, Markus T, Möbius, Wiebke, Bohnsack, Katherine E, Outeiro, Tiago F, Braus, Gerhard H

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Navigating through the complexities of synucleinopathies: Insights into pathogenesis, heterogeneity, and future perspectives von Lázaro, Diana F., Lee, Virginia M.-Y.

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Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells von Perfeito, Rita, Lázaro, Diana F., Outeiro, Tiago F., Rego, A. Cristina

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Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo von Dominguez-Meijide, Antonio, Parrales, Valeria, Vasili, Eftychia, González-Lizárraga, Florencia, König, Annekatrin, Lázaro, Diana F., Lannuzel, Annie, Haik, Stéphane, Del Bel, Elaine, Chehín, Rosana, Raisman-Vozari, Rita, Michel, Patrick P., Bizat, Nicolas, Outeiro, Tiago Fleming

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C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease von Kleinknecht, Alexandra, Popova, Blagovesta, Lázaro, Diana F, Pinho, Raquel, Valerius, Oliver, Outeiro, Tiago F, Braus, Gerhard H

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In silico analysis of the aggregation propensity of the SARS-CoV-2 proteome: Insight into possible cellular pathologies von Flores-León, Manuel, Lázaro, Diana F., Shvachiy, Liana, Krisko, Anita, Outeiro, Tiago F.

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Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function von Paiva, Isabel, Jain, Gaurav, Lázaro, Diana F., Jerčić, Kristina Gotovac, Hentrich, Thomas, Kerimoglu, Cemil, Pinho, Raquel, Szegő, Èva M., Burkhardt, Susanne, Capece, Vincenzo, Halder, Rashi, Islam, Rezaul, Xylaki, Mary, Caldi Gomes, Lucas A., Roser, Anna-Elisa, Lingor, Paul, Schulze-Hentrich, Julia M., Borovečki, Fran, Fischer, André, Outeiro, Tiago F.

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X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper()/copper()-α-Syn interactions and affects protein aggregation in a cellular mode... von Cukierman, Daphne S, Lázaro, Diana F, Sacco, Pamela, Ferreira, Patrícia R, Diniz, Renata, Fernández, Claudio O, Outeiro, Tiago F, Rey, Nicolás A

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Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in Cells von Moree, Ben, Yin, Guowei, Lázaro, Diana F., Munari, Francesca, Strohäker, Timo, Giller, Karin, Becker, Stefan, Outeiro, Tiago F., Zweckstetter, Markus, Salafsky, Joshua

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A new MAP-Rasagiline conjugate reduces α-synuclein inclusion formation in a cell model von Vale, Nuno, Alves, Cláudia, Sharma, Vaishali, Lázaro, Diana F., Silva, Sara, Gomes, Paula, Outeiro, Tiago Fleming

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Editorial: Protein Misfolding and Spreading Pathology in Neurodegenerative Diseases von Lázaro, Diana F, Bellucci, Arianna, Brundin, Patrik, Outeiro, Tiago F

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α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner von Yin, Guowei, Lopes da Fonseca, Tomas, Eisbach, Sibylle E, Anduaga, Ane Martín, Breda, Carlo, Orcellet, Maria L, Szegő, Éva M, Guerreiro, Patricia, Lázaro, Diana F, Braus, Gerhard H, Fernandez, Claudio O, Griesinger, Christian, Becker, Stefan, Goody, Roger S, Itzen, Aymelt, Giorgini, Flaviano, Outeiro, Tiago F, Zweckstetter, Markus

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Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells von Gustafsson, Gabriel, Lööv, Camilla, Persson, Emma, Lázaro, Diana F., Takeda, Shuko, Bergström, Joakim, Erlandsson, Anna, Sehlin, Dag, Balaj, Leonora, György, Bence, Hallbeck, Martin, Outeiro, Tiago F., Breakefield, Xandra O., Hyman, Bradley T., Ingelsson, Martin

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The effects of the novel A53E alpha-synuclein mutation on its oligomerization and aggregation von Lázaro, Diana F, Dias, Mariana Castro, Carija, Anita, Navarro, Susanna, Madaleno, Carolina Silva, Tenreiro, Sandra, Ventura, Salvador, Outeiro, Tiago F

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Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation von Popova, Blagovesta, Wang, Dan, Rajavel, Abirami, Dhamotharan, Karthikeyan, Lázaro, Diana F, Gerke, Jennifer, Uhrig, Joachim F, Hoppert, Michael, Outeiro, Tiago F, Braus, Gerhard H

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