Empirical methods for the validation of time-to-event mathematical models taking into account uncertainty and variability: application to EGFR + lung adenocarcinoma von Jacob, Evgueni, Perrillat-Mercerot, Angélique, Palgen, Jean-Louis, L'Hostis, Adèle, Ceres, Nicoletta, Boissel, Jean-Pierre, Bosley, Jim, Monteiro, Claudio, Kahoul, Riad

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Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting von Tantale, Katjana, Garcia-Oliver, Encar, Robert, Marie-Cécile, L’Hostis, Adèle, Yang, Yueyuxiao, Tsanov, Nikolay, Topno, Rachel, Gostan, Thierry, Kozulic-Pirher, Alja, Basu-Shrivastava, Meenakshi, Mukherjee, Kamalika, Slaninova, Vera, Andrau, Jean-Christophe, Mueller, Florian, Basyuk, Eugenia, Radulescu, Ovidiu, Bertrand, Edouard

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Integration of Heterogeneous Biological Data in Multiscale Mechanistic Model Calibration: Application to Lung Adenocarcinoma von Palgen, Jean-Louis, Perrillat-Mercerot, Angélique, Ceres, Nicoletta, Peyronnet, Emmanuel, Coudron, Matthieu, Tixier, Eliott, Illigens, Ben M. W., Bosley, Jim, L’Hostis, Adèle, Monteiro, Claudio

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Comparing the Efficacy of Two Generations of EGFR-TKIs: An Integrated Drug-Disease Mechanistic Model Approach in EGFR-Mutated Lung Adenocarcinoma von Darré, Hippolyte, Masson, Perrine, Nativel, Arnaud, Villain, Laura, Lefaudeux, Diane, Couty, Claire, Martin, Bastien, Jacob, Evgueni, Duruisseaux, Michaël, Palgen, Jean-Louis, Monteiro, Claudio, L'Hostis, Adèle

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Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in EGFR-mutant lung adenocarcinoma von L’Hostis, Adèle, Palgen, Jean-Louis, Perrillat-Mercerot, Angélique, Peyronnet, Emmanuel, Jacob, Evgueni, Bosley, James, Duruisseaux, Michaël, Toueg, Raphaël, Lefèvre, Lucile, Kahoul, Riad, Ceres, Nicoletta, Monteiro, Claudio

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Implementation of a knowledge-based mechanistic model of EGFR-mutant lung adenocarcinoma that considers tumor heterogeneity and metastases to reproduce disease progression upon EGF... von Darré, Hippolyte, Masson, Perrine, Villain, Laura, Couty, Claire, Martin, Bastien, Jacob, Evgueni, Todea, Andreea, Toueg, Raphael, Duruisseaux, Michaël, Palgen, Jean-Louis, Monteiro, Claudio, L'Hostis, Adèle

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Multiscale in silico knowledge-based model predicts tumor growth in advanced EGFR+ NSCLC patients on gefitinib von L'Hostis, Adèle, Palgen, Jean-Louis, Ceres, Nicoletta, Perrillat-Mercerot, Angelique, Peyronnet, Emmanuel, Jacob, Evgueni, Kahoul, Riad, Coudron, Matthieu, Lefevre, Lucile, Toueg, Raphael, Todea, Andreea, Hommel, Marc, Boissel, Jean-Pierre, Bosley, Jim, Duruisseaux, Michaël, Monteiro, Claudio

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Abstract 857: Assuming tumors have a spherical shape in modeling EGFR mutant lung adenocarcinoma: Impact on modeled clinical outcome von Kleine-Schultjann, Julie, Gómez, Germán, L'Hostis, Adèle, Palgen, Jean-Louis, Monteiro, Claudio, Masson, Perrine

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Abstract 859: Simulations of tumor heterogeneity impact on treatment response using a mechanistic model of EGFR-mutant lung adenocarcinoma von Masson, Perrine, Couty, Claire, Nativel, Arnaud, Jacob, Evgueni, Toueg, Raphaël, Duruisseaux, Michaël, L'Hostis, Adèle, Palgen, Jean-Louis, Monteiro, Claudio

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Abstract 3362: Multiscale EGFR mutated NSCLC tumor heterogeneity knowledge-based model predicts tumor growth under gefitinib: An avenue to in silico clinical trial von Duruisseaux, Michael, L'Hostis, Adèle, Peyronnet, Emmanuel, Jacob, Evgueni, Illigens, Ben M.W., Bosley, Jim, Kahoul, Riad, Palgen, Jean-Louis, Monteiro, Claudio

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Abstract 856: Comparison of the effect of two EGFR-TKI in patients with EGFR-mutant lung adenocarcinoma using in silico clinical trials von Darré, Hippolyte, Martin, Bastien, Hammami, Firas, Nativel, Arnaud, Lefaudeux, Diane, Toueg, Raphaël, Duruisseaux, Michaël, Palgen, Jean-Louis, Masson, Perrine, L'Hostis, Adèle, Ceres, Nicoletta, Monteiro, Claudio

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Abstract 4287: The combination of statistical methods to compare observed and simulated data allowed to assess effectively the validity of mathematical model predictions in a conte... von Jacob, Evgueni, Villain, Laura, Ceres, Nicoletta, Palgen, Jean-Louis, L'Hostis, Adele, Monteiro, Claudio, Kahoul, Riad

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Synergistic effect between molybdenum back contact and CIGS absorber in the degradation of solar cells von Debono, Adèle, L'Hostis, Hortense, Rebai, Amelle, Mysliu, Erlind, Odnevall, Inger, Schneider, Nathanaelle, Guillemoles, Jean‐François, Erbe, Andreas, Volovitch, Polina

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Synergistic effect between molybdenum back contact and CIGS absorber in the degradation of solar cells von Debono, Adèle, L'Hostis, Hortense, Rebai, Amelle, Mysliu, Erlind, Odnevall, Inger, Schneider, Nathanaelle, Guillemoles, Jean-François, Erbe, Andreas, Volovitch, Polina

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