Biological stoichiometry in human cancer von Elser, James J, Kyle, Marcia M, Smith, Marilyn S, Nagy, John D

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Operationalizing the social-ecological systems framework to assess sustainability von Leslie, Heather M., Basurto, Xavier, Nenadovic, Mateja, Sievanen, Leila, Cavanaugh, Kyle C., Cota-Nieto, Juan José, Erisman, Brad E., Finkbeiner, Elena, Hinojosa-Arango, Gustavo, Moreno-Báez, Marcia, Nagavarapu, Sriniketh, Reddy, Sheila M. W., Sánchez-Rodríguez, Alexandra, Siegel, Katherine, Ulibarria-Valenzuela, José Juan, Weaver, Amy Hudson, Aburto-Oropeza, Octavio

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Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation von Ron-Harel, Noga, Santos, Daniel, Ghergurovich, Jonathan M., Sage, Peter T., Reddy, Anita, Lovitch, Scott B., Dephoure, Noah, Satterstrom, F. Kyle, Sheffer, Michal, Spinelli, Jessica B., Gygi, Steven, Rabinowitz, Joshua D., Sharpe, Arlene H., Haigis, Marcia C.

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Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice von Ron-Harel, Noga, Notarangelo, Giulia, Ghergurovich, Jonathan M., Paulo, Joao A., Sage, Peter T., Santos, Daniel, Satterstrom, F. Kyle, Gygi, Steven P., Rabinowitz, Joshua D., Sharpe, Arlene H., Haigis, Marcia C.

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SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes von Li, Yijia, Schneider, Alexis M, Mehta, Arnav, Sade-Feldman, Moshe, Kays, Kyle R, Gentili, Matteo, Charland, Nicole C, Gonye, Anna Lk, Gushterova, Irena, Khanna, Hargun K, LaSalle, Thomas J, Lavin-Parsons, Kendall M, Lilley, Brendan M, Lodenstein, Carl L, Manakongtreecheep, Kasidet, Margolin, Justin D, McKaig, Brenna N, Parry, Blair A, Rojas-Lopez, Maricarmen, Russo, Brian C, Sharma, Nihaarika, Tantivit, Jessica, Thomas, Molly F, Regan, James, Flynn, James P, Villani, Alexandra-Chloé, Hacohen, Nir, Goldberg, Marcia B, Filbin, Michael R, Li, Jonathan Z

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Shifts in Lake N:P Stoichiometry and Nutrient Limitation Driven by Atmospheric Nitrogen Deposition von Elser, James J, Andersen, Tom, Baron, Jill S, Bergström, Ann-Kristin, Jansson, Mats, Kyle, Marcia, Nydick, Koren R, Steger, Laura, Hessen, Dag O

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FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation von Junqueira, Caroline, Crespo, Ângela, Ranjbar, Shahin, de Lacerda, Luna B., Lewandrowski, Mercedes, Ingber, Jacob, Parry, Blair, Ravid, Sagi, Clark, Sarah, Schrimpf, Marie Rose, Ho, Felicia, Beakes, Caroline, Margolin, Justin, Russell, Nicole, Kays, Kyle, Boucau, Julie, Das Adhikari, Upasana, Vora, Setu M., Leger, Valerie, Gehrke, Lee, Henderson, Lauren A., Janssen, Erin, Kwon, Douglas, Sander, Chris, Abraham, Jonathan, Goldberg, Marcia B., Wu, Hao, Mehta, Gautam, Bell, Steven, Goldfeld, Anne E., Filbin, Michael R., Lieberman, Judy

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Alveolar, Endothelial, and Organ Injury Marker Dynamics in Severe COVID-19 von Leisman, Daniel E, Mehta, Arnav, Thompson, B Taylor, Charland, Nicole C, Gonye, Anna L K, Gushterova, Irena, Kays, Kyle R, Khanna, Hargun K, LaSalle, Thomas J, Lavin-Parsons, Kendall M, Lilley, Brendan M, Lodenstein, Carl L, Manakongtreecheep, Kasidet, Margolin, Justin D, McKaig, Brenna N, Rojas-Lopez, Maricarmen, Russo, Brian C, Sharma, Nihaarika, Tantivit, Jessica, Thomas, Molly F, Parry, Blair Alden, Villani, Alexandra-Chloé, Sade-Feldman, Moshe, Hacohen, Nir, Filbin, Michael R, Goldberg, Marcia B

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Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions von Filbin, Michael R., Mehta, Arnav, Schneider, Alexis M., Kays, Kyle R., Guess, Jamey R., Gentili, Matteo, Fenyves, Bánk G., Charland, Nicole C., Gonye, Anna L.K., Gushterova, Irena, Khanna, Hargun K., LaSalle, Thomas J., Lavin-Parsons, Kendall M., Lilley, Brendan M., Lodenstein, Carl L., Manakongtreecheep, Kasidet, Margolin, Justin D., McKaig, Brenna N., Rojas-Lopez, Maricarmen, Russo, Brian C., Sharma, Nihaarika, Tantivit, Jessica, Thomas, Molly F., Gerszten, Robert E., Heimberg, Graham S., Hoover, Paul J., Lieb, David J., Lin, Brian, Ngo, Debby, Pelka, Karin, Reyes, Miguel, Smillie, Christopher S., Waghray, Avinash, Wood, Thomas E., Zajac, Amanda S., Jennings, Lori L., Grundberg, Ida, Bhattacharyya, Roby P., Parry, Blair Alden, Villani, Alexandra-Chloé, Sade-Feldman, Moshe, Hacohen, Nir, Goldberg, Marcia B.

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Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3 von Gonzalez Herrera, Karina N., Zaganjor, Elma, Ishikawa, Yoshinori, Spinelli, Jessica B., Yoon, Haejin, Lin, Jia-Ren, Satterstrom, F. Kyle, Ringel, Alison, Mulei, Stacy, Souza, Amanda, Gorham, Joshua M., Benson, Craig C., Seidman, Jonathan G., Sorger, Peter K., Clish, Clary B., Haigis, Marcia C.

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Towards an integrative view of virus phenotypes von DeLong, John P., Al-Sammak, Maitham A., Al-Ameeli, Zeina T., Dunigan, David D., Edwards, Kyle F., Fuhrmann, Jeffry J., Gleghorn, Jason P., Li, Hanqun, Haramoto, Kona, Harrison, Amelia O., Marston, Marcia F., Moore, Ryan M., Polson, Shawn W., Ferrell, Barbra D., Salsbery, Miranda E., Schvarcz, Christopher R., Shirazi, Jasmine, Steward, Grieg F., Van Etten, James L., Wommack, K. Eric

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Variants in HNRNPH2 on the X Chromosome Are Associated with a Neurodevelopmental Disorder in Females von Bain, Jennifer M., Cho, Megan T., Telegrafi, Aida, Wilson, Ashley, Brooks, Susan, Botti, Christina, Gowans, Gordon, Autullo, Leigh Anne, Krishnamurthy, Vidya, Willing, Marcia C., Toler, Tomi L., Ben-Zev, Bruria, Elpeleg, Orly, Shen, Yufeng, Retterer, Kyle, Monaghan, Kristin G., Chung, Wendy K.

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Cancer testis antigen burden (CTAB): a novel biomarker of tumor-associated antigens in lung cancer von Seager, R J, Senosain, Maria-Fernanda, Van Roey, Erik, Gao, Shuang, DePietro, Paul, Nesline, Mary K, Dash, Durga Prasad, Zhang, Shengle, Ko, Heidi, Hastings, Stephanie B, Strickland, Kyle C, Previs, Rebecca A, Jensen, Taylor J, Eisenberg, Marcia, Caveney, Brian J, Severson, Eric A, Ramkissoon, Shakti, Conroy, Jeffrey M, Pabla, Sarabjot

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The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity von Baumgartner, Christina K., Ebrahimi-Nik, Hakimeh, Iracheta-Vellve, Arvin, Hamel, Keith M., Olander, Kira E., Davis, Thomas G. R., McGuire, Kathleen A., Halvorsen, Geoff T., Avila, Omar I., Patel, Chirag H., Kim, Sarah Y., Kammula, Ashwin V., Muscato, Audrey J., Halliwill, Kyle, Geda, Prasanthi, Klinge, Kelly L., Xiong, Zhaoming, Duggan, Ryan, Mu, Liang, Yeary, Mitchell D., Patti, James C., Balon, Tyler M., Mathew, Rebecca, Backus, Carey, Kennedy, Domenick E., Chen, Angeline, Longenecker, Kenton, Klahn, Joseph T., Hrusch, Cara L., Krishnan, Navasona, Hutchins, Charles W., Dunning, Jax P., Bulic, Marinka, Tiwari, Payal, Colvin, Kayla J., Chuong, Cun Lan, Kohnle, Ian C., Rees, Matthew G., Boghossian, Andrew, Ronan, Melissa, Roth, Jennifer A., Wu, Meng-Ju, Suermondt, Juliette S. M. T., Knudsen, Nelson H., Cheruiyot, Collins K., Sen, Debattama R., Griffin, Gabriel K., Golub, Todd R., El-Bardeesy, Nabeel, Decker, Joshua H., Yang, Yi, Guffroy, Magali, Fossey, Stacey, Trusk, Patricia, Sun, Im-Meng, Liu, Yue, Qiu, Wei, Sun, Qi, Paddock, Marcia N., Farney, Elliot P., Matulenko, Mark A., Beauregard, Clay, Frost, Jennifer M., Yates, Kathleen B., Kym, Philip R., Manguso, Robert T.

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Case report: Single gene testing and comprehensive genomic profiling in non-small cell lung cancer-a case series of divergent results from a large reference laboratory von Strickland, Kyle C, Nesline, Mary K, Previs, Rebecca A, Ko, Heidi, Cooper, Maureen, Rushton, Jennifer R, Wallen, Zachary D, Pabla, Sarabjot, Conroy, Jeffrey M, Sausen, Mark, Saini, Kamal S, Cantini, Luca, Jensen, Taylor J, Caveney, Brian J, Eisenberg, Marcia, Severson, Eric A, Ramkissoon, Shakti

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Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients von LaSalle, Thomas J, Gonye, Anna L K, Freeman, Samuel S, Kaplonek, Paulina, Gushterova, Irena, Kays, Kyle R, Manakongtreecheep, Kasidet, Tantivit, Jessica, Rojas-Lopez, Maricarmen, Russo, Brian C, Sharma, Nihaarika, Thomas, Molly F, Lavin-Parsons, Kendall M, Lilly, Brendan M, Mckaig, Brenna N, Charland, Nicole C, Khanna, Hargun K, Lodenstein, Carl L, Margolin, Justin D, Blaum, Emily M, Lirofonis, Paola B, Revach, Or-Yam, Mehta, Arnav, Sonny, Abraham, Bhattacharyya, Roby P, Parry, Blair Alden, Goldberg, Marcia B, Alter, Galit, Filbin, Michael R, Villani, Alexandra-Chloé, Hacohen, Nir, Sade-Feldman, Moshe

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GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway von Wallin, Jeffrey J, Edgar, Kyle A, Guan, Jane, Berry, Megan, Prior, Wei Wei, Lee, Leslie, Lesnick, John D, Lewis, Cristina, Nonomiya, Jim, Pang, Jodie, Salphati, Laurent, Olivero, Alan G, Sutherlin, Daniel P, O'Brien, Carol, Spoerke, Jill M, Patel, Sonal, Lensun, Letitia, Kassees, Robert, Ross, Leanne, Lackner, Mark R, Sampath, Deepak, Belvin, Marcia, Friedman, Lori S

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Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes von Wallin, Jeffrey J, Guan, Jane, Edgar, Kyle A, Zhou, Wei, Francis, Ross, Torres, Anthony C, Haverty, Peter M, Eastham-Anderson, Jeffrey, Arena, Sabrina, Bardelli, Alberto, Griffin, Sue, Goodall, John E, Grimshaw, Kyla M, Hoeflich, Klaus P, Torrance, Christopher, Belvin, Marcia, Friedman, Lori S

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Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome von Parks, Annette L, Cook, Kevin R, Belvin, Marcia, Dompe, Nicholas A, Fawcett, Robert, Huppert, Kari, Tan, Lory R, Winter, Christopher G, Bogart, Kevin P, Deal, Jennifer E, Deal-Herr, Megan E, Grant, Deanna, Marcinko, Marie, Miyazaki, Wesley Y, Robertson, Stephanie, Shaw, Kenneth J, Tabios, Mariano, Vysotskaia, Valentina, Zhao, Lora, Andrade, Rachel S, Edgar, Kyle A, Howie, Elizabeth, Killpack, Keith, Milash, Brett, Norton, Amanda, Thao, Doua, Whittaker, Kellie, Winner, Millicent A, Friedman, Lori, Margolis, Jonathan, Singer, Matthew A, Kopczynski, Casey, Curtis, Daniel, Kaufman, Thomas C, Plowman, Gregory D, Duyk, Geoffrey, Francis-Lang, Helen L

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A core domain set for pyoderma gangrenosum trial outcomes: an international eDelphi and consensus study from the UPGRADE initiative von Jacobson, Michael E, Rick, Jonathan W, Gerbens, Louise A A, Baghoomian, Wenelia, Gould, Lisa J, Marzano, Angelo V, Chen, Diana M, Oakes, Debbie L, Dissemond, Joachim, Yamamoto, Toshiyuki, Shinkai, Kanade, Nolan, Barbara, Lobato, Dan, Thomas, Kim S, Ortega-Loayza, Alex G

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