Phytohormones, Isoprenoids, and Role of the Apicoplast in Recovery from Dihydroartemisinin-Induced Dormancy of Plasmodium falciparum von Duvalsaint, Marvin, Kyle, Dennis E

Volltext

Artemisinin-Induced Dormancy in Plasmodium falciparum: Duration, Recovery Rates, and Implications in Treatment Failure von Teuscher, Franka, Gatton, Michelle L., Chen, Nanhua, Peters, Jennifer, Kyle, Dennis E., Cheng, Qin

Volltext

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae von Rice, Christopher A., Colon, Beatrice L., Chen, Emily, Hull, Mitchell, Kyle, Dennis E.

Volltext

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis von Baragan˜a, Beatriz, Forte, Barbara, Choi, Ryan, Hewitt, Stephen Nakazawa, Bueren-Calabuig, Juan A., Pisco, Joa˜o Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O’Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.

Volltext

Characterization of the extracellular vesicles, ultrastructural morphology, and intercellular interactions of multiple clinical isolates of the brain-eating amoeba, Naegleria fowle... von Russell, A. Cassiopeia, Bush, Peter, Grigorean, Gabriela, Kyle, Dennis E.

Volltext

Artemisinin-resistant Plasmodium falciparum parasites exhibit altered patterns of development in infected erythrocytes von Hott, Amanda, Casandra, Debora, Sparks, Kansas N, Morton, Lindsay C, Castanares, Geocel-Grace, Rutter, Amanda, Kyle, Dennis E

Volltext

Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei von LaCrue, Alexis N, Scheel, Misty, Kennedy, Katherine, Kumar, Nikesh, Kyle, Dennis E

Volltext

The influence of oviposition status on measures of transmission potential in malaria-infected mosquitoes depends on sugar availability von Shiau, Justine C, Garcia-Diaz, Nathan, Kyle, Dennis E, Pathak, Ashutosh K

Volltext

Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity von Iyamu, Iredia D., Zhao, Yingzhao, Parvatkar, Prakash T., Roberts, Bracken F., Casandra, Debora R., Wojtas, Lukasz, Kyle, Dennis E., Chakrabarti, Debopam, Manetsch, Roman

Volltext

Streamlining sporozoite isolation from mosquitoes by leveraging the dynamics of migration to the salivary glands von Pathak, Ashutosh K, Shiau, Justine C, Franke-Fayard, Blandine, Shollenberger, Lisa M, Harn, Donald A, Kyle, Dennis E, Murdock, Courtney C

Volltext

Differential Growth Rates and In Vitro Drug Susceptibility to Currently Used Drugs for Multiple Isolates of Naegleria fowleri von Russell, A Cassiopeia, Kyle, Dennis E

Volltext

The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design von Phan, Isabelle Q., Rice, Christopher A., Craig, Justin, Noorai, Rooksana E., McDonald, Jacquelyn R., Subramanian, Sandhya, Tillery, Logan, Barrett, Lynn K., Shankar, Vijay, Morris, James C., Van Voorhis, Wesley C., Kyle, Dennis E., Myler, Peter J.

Volltext

Role of pfmdr1 Amplification and Expression in Induction of Resistance to Artemisinin Derivatives in Plasmodium falciparum von CHAVCHICH, Marina, GERENA, Lucia, PETERS, Jennifer, NANHUA CHEN, QIN CHENG, KYLE, Dennis E

Volltext

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba von Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W., Osterhout, Bram, Tran, Nathan L., Xu, Lily, Young, Ryan M., Craig, Justin, Chun, Ian, Dranow, David M., Abendroth, Jan, Delker, Silvia L., Davies, Douglas R., Mayclin, Stephen J., Calhoun, Brandy, Bolejack, Madison J., Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D., Myler, Peter J., Edwards, Thomas E., Kyle, Dennis E., Rice, Christopher A., Morris, James C., Leahy, James W., Manetsch, Roman, Barrett, Lynn K., Smith, Craig L., Van Voorhis, Wesley C.

Volltext

Antileishmanial activity of a series of N²,N⁴-disubstituted quinazoline-2,4-diamines von Van Horn, Kurt S, Zhu, Xiaohua, Pandharkar, Trupti, Yang, Sihyung, Vesely, Brian, Vanaerschot, Manu, Dujardin, Jean-Claude, Rijal, Suman, Kyle, Dennis E, Wang, Michael Zhuo, Werbovetz, Karl A, Manetsch, Roman

Volltext

Phenotypic and Genotypic Analysis of In Vitro-Selected Artemisinin-Resistant Progeny of Plasmodium falciparum von Tucker, Matthew S, Mutka, Tina, Sparks, Kansas, Patel, Janus, Kyle, Dennis E

Volltext

Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets von Ruberto, Anthony A., Maher, Steven P., Vantaux, Amélie, Joyner, Chester J., Bourke, Caitlin, Balan, Balu, Jex, Aaron, Mueller, Ivo, Witkowski, Benoit, Kyle, Dennis E.

Volltext

Chemistry and Bioactivity of the Deep-Water Antarctic Octocoral Alcyonium sp von Limon, Anne-Claire D, Patabendige, Hiran M L W, Azhari, Ala, Sun, Xingmin, Kyle, Dennis E, Wilson, Nerida G, Baker, Bill J

Volltext

Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii von Rice, Christopher A., Troth, Emma, Russell, A. Cassiopeia, Kyle, Dennis E.

Volltext

Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure von Codd, Andrea, Teuscher, Franka, Kyle, Dennis E, Cheng, Qin, Gatton, Michelle L

Volltext