Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis von El-Naggar, Amal M., Veinotte, Chansey J., Cheng, Hongwei, Grunewald, Thomas G.P., Negri, Gian Luca, Somasekharan, Syam Prakash, Corkery, Dale P., Tirode, Franck, Mathers, Joan, Khan, Debjit, Kyle, Alastair H., Baker, Jennifer H., LePard, Nancy E., McKinney, Steven, Hajee, Shamil, Bosiljcic, Momir, Leprivier, Gabriel, Tognon, Cristina E., Minchinton, Andrew I., Bennewith, Kevin L., Delattre, Olivier, Wang, Yuzhuo, Dellaire, Graham, Berman, Jason N., Sorensen, Poul H.

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Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically von Chafe, Shawn C, McDonald, Paul C, Saberi, Saeed, Nemirovsky, Oksana, Venkateswaran, Geetha, Burugu, Samantha, Gao, Dongxia, Delaidelli, Alberto, Kyle, Alastair H, Baker, Jennifer H E, Gillespie, Jordan A, Bashashati, Ali, Minchinton, Andrew I, Zhou, Youwen, Shah, Sohrab P, Dedhar, Shoukat

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DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost von Wang, Taixiang, Kyle, Alastair H., Baker, Jennifer H. E., Liu, Nannan A., Banáth, Judit P., Minchinton, Andrew I.

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The Prognostic Impact of CD163-Positive Macrophages in Follicular Lymphoma: A Study from the BC Cancer Agency and the Lymphoma Study Association von Kridel, Robert, Xerri, Luc, Gelas-Dore, Bénédicte, Tan, King, Feugier, Pierre, Vawda, Ayesha, Canioni, Danielle, Farinha, Pedro, Boussetta, Sami, Moccia, Alden A, Brice, Pauline, Chavez, Elizabeth A, Kyle, Alastair H, Scott, David W, Sanders, Ashley D, Fabiani, Bettina, Slack, Graham W, Minchinton, Andrew I, Haioun, Corinne, Connors, Joseph M, Sehn, Laurie H, Steidl, Christian, Gascoyne, Randy D, Salles, Gilles

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Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling von Chang, Linda, Noseda, Michela, Higginson, Michelle, Ly, Michelle, Patenaude, Alexandre, Fuller, Megan, Kyle, Alastair H, Minchinton, Andrew I, Puri, Mira C, Dumont, Daniel J, Karsan, Aly

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Limited Tissue Penetration of Taxanes: A Mechanism for Resistance in Solid Tumors von KYLE, Alastair H, HUXHAM, Lynsey A, YEOMAN, Devon M, MINCHINTON, Andrew I

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Direct Visualization of Heterogeneous Extravascular Distribution of Trastuzumab in Human Epidermal Growth Factor Receptor Type 2 Overexpressing Xenografts von BAKER, Jennifer H. E, LINDQUIST, Kirstin E, HUXHAM, Lynsey A, KYLE, Alastair H, SY, Jonathan T, MINCHINTON, Andrew I

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Targeting Quiescent Tumor Cells via Oxygen and IGF-I Supplementation von KYLE, Alastair H, BAKER, Jennifer H. E, MINCHINTON, Andrew I

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Vascularization predicts overall survival and risk of transformation in follicular lymphoma von FARINHA, Pedro, KYLE, Alastair H, MINCHINTON, Andrew I, CONNORS, Joseph M, KARSAN, Aly, GASCOYNE, Randy D

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Angiopoietin-2 Functions as a Tie2 Agonist in Tumor Models, Where It Limits the Effects of VEGF Inhibition von DALY, Christopher, EICHTEN, Alexandra, THURSTON, Gavin, CASTANARO, Carla, PASNIKOWSKI, Elizabeth, ADLER, Alexander, LALANI, Alshad S, PAPADOPOULOS, Nicholas, KYLE, Alastair H, MINCHINTON, Andrew I, YANCOPOULOS, George D

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Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin von Baker, Jennifer H E, Kyle, Alastair H, Bartels, Kirsten L, Methot, Stephen P, Flanagan, Erin J, Balbirnie, Andrew, Cran, Jordan D, Minchinton, Andrew I

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Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK) von Edwards, Lincoln A, Woo, Janet, Huxham, Lynsey A, Verreault, Maite, Dragowska, Wieslawa H, Chiu, Gigi, Rajput, Ashish, Kyle, Alastair H, Kalra, Jessica, Yapp, Donald, Yan, Hong, Minchinton, Andrew I, Huntsman, David, Daynard, Tim, Waterhouse, Dawn N, Thiessen, B, Dedhar, Shoukat, Bally, Marcel B

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Detection of FLASH-radiotherapy tissue sparing in a 3D-spheroid model using DNA damage response markers von Kyle, Alastair H., Karan, Tania, Baker, Jennifer H.E., Püspöky Banáth, Judit, Wang, Taixiang, Liu, Anam, Mendez, Claudia, Peter Petric, M., Duzenli, Cheryl, Minchinton, Andrew I.

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DNA-PK inhibitor AZD7648 is a more portent radiosensitizer than PARP inhibitor Olaparib in BRCA1/2 deficient tumors von Wang, Taixiang, Kyle, Alastair H., Baker, Jennifer H.E., Liu, Nannan A., Banáth, Judit P., Teymori, Sevin, Minchinton, Andrew I.

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Silencing Bcl-2 in models of mantle cell lymphoma is associated with decreases in cyclin D1, nuclear factor-κB, p53, bax, and p27 levels von Tucker, Catherine A., Kapanen, Anita I., Chikh, Ghania, Hoffman, Brad G., Kyle, Alastair H., Wilson, Ian M., Masin, Dana, Gascoyne, Randy D., Bally, Marcel, Klasa, Richard J.

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Detecting Vascular-Targeting Effects of the Hypoxic Cytotoxin Tirapazamine in Tumor Xenografts Using Magnetic Resonance Imaging von Bains, Lauren J., M.Sc, Baker, Jennifer H.E., B.Sc, Kyle, Alastair H., Ph.D, Minchinton, Andrew I., Ph.D, Reinsberg, Stefan A., Ph.D

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Endothelial-Specific Notch Blockade Inhibits Vascular Function and Tumor Growth through an eNOS-Dependent Mechanism von PATENAUDE, Alexandre, FULLER, Megan, TONG, Jade, MINCHINTON, Andrew I, KARSAN, Aly, CHANG, Linda, WONG, Fred, PALIOURAS, Grigorios, SHAW, Rebecca, KYLE, Alastair H, UMLANDT, Patricia, BAKER, Jennifer H. E, DIAZ, Erika

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The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular functi... von Yapp, Donald T., Wong, May Q., Kyle, Alastair H., Valdez, Shannon M., Tso, Jenny, Yung, Andrew, Kozlowski, Piotr, Owen, David A., Buczkowski, Andrzej K., Chung, Stephen W., Scudamore, Charles H., Minchinton, Andrew I., Ng, Sylvia S. W.

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Characterization of Three-Dimensional Tissue Cultures Using Electrical Impedance Spectroscopy von Kyle, Alastair H., Chan, Carmel T.O., Minchinton, Andrew I.

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Tissue penetration and activity of camptothecins in solid tumor xenografts von Kyle, Alastair H, Baker, Jennifer H E, Gandolfo, Maria-Jose, Reinsberg, Stefan A, Minchinton, Andrew I

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