Cross-Activation of Regulatory T Cells by Self Antigens Limits Self-Reactive and Activated CD8+ T Cell Responses von Cho, Eunjung, Han, Seongeun, Eom, Hyeon Seok, Lee, Sang-Jin, Han, Chungyong, Singh, Rohit, Kim, Seon-Hee, Park, Bo-Mi, Kim, Byoung-Gie, Kim, Young H, Kwon, Byoung S, Nam, Ki Taek, Choi, Beom K

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Targeting 4-1BB and PD-L1 induces potent and durable antitumor immunity in B-cell lymphoma von Wang, Yichen, Zhang, Xuyao, Xu, Caili, Nan, Yanyang, Fan, Jiajun, Zeng, Xian, Kwon, Byoung S, Ju, Dianwen

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Adoptive immunotherapy with transient anti-CD4 treatment enhances anti-tumor response by increasing IL-18Rαhi CD8+ T cells von Kim, Seon-Hee, Cho, Eunjung, Kim, Yu I., Han, Chungyong, Choi, Beom K., Kwon, Byoung S.

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Desensitized chimeric antigen receptor T cells selectively recognize target cells with enhanced antigen expression von Han, Chungyong, Sim, Su-Jung, Kim, Seon-Hee, Singh, Rohit, Hwang, Sunhee, Kim, Yu I., Park, Sang H., Kim, Kwang H., Lee, Don G., Oh, Ho S., Lee, Sangeun, Kim, Young H., Choi, Beom K., Kwon, Byoung S.

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4-1BB Signaling Enhances Primary and Secondary Population Expansion of CD8+ T Cells by Maximizing Autocrine IL-2/IL-2 Receptor Signaling von Oh, Ho S, Choi, Beom K, Kim, Young H, Lee, Don G, Hwang, Sunhee, Lee, Myoung J, Park, Sang H, Bae, Yong-Soo, Kwon, Byoung S

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Extracellular stimulation of VSIG4/complement receptor Ig suppresses intracellular bacterial infection by inducing autophagy von Kim, Kwang H., Choi, Beom K., Kim, Young H., Han, Chungyong, Oh, Ho S., Lee, Don G., Kwon, Byoung S.

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4-1BB signaling activates the t cell factor 1 effector/β-catenin pathway with delayed kinetics via ERK signaling and delayed PI3K/AKT activation to promote the proliferation of CD8... von Lee, Do Y, Choi, Beom K, Lee, Don G, Kim, Young H, Kim, Chang H, Lee, Seung J, Kwon, Byoung S

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Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation von Kim, Hye J., Lee, Jong S., Kim, Jung D., Cha, Hee J., Kim, Ahra, Lee, Sun K., Lee, Sang C., Kwon, Byoung S., Mittler, Robert S., Cho, Hong R., Kwon, Byungsuk

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TLR2 signaling in tubular epithelial cells regulates NK cell recruitment in kidney ischemia-reperfusion injury von Kim, Hye J, Lee, Jong S, Kim, Ahra, Koo, Sumi, Cha, Hee J, Han, Jae-A, Do, Yoonkyung, Kim, Kyung M, Kwon, Byoung S, Mittler, Robert S, Cho, Hong R, Kwon, Byungsuk

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CD137 (4-1BB) Deficiency Reduces Atherosclerosis in Hyperlipidemic Mice von HYUNG JUN JEON, CHOI, Jae-Hoon, JEONG EUY PARK, PARK, Hyun-Young, KYUBUM KWACK, BEOM KYU CHOI, KWON, Byoung S, GOO TAEG OH, JUNG, In-Hyuk, PARK, Jong-Gil, LEE, Mi-Ran, LEE, Mi-Ni, KIM, Bora, YOO, Ji-Young, JEONG, Se-Jin, KIM, Dae-Yong

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The repopulating cancer cells in melanoma are characterized by increased mitochondrial membrane potential von Lee, Don G, Choi, Beom K, Kim, Young H, Oh, Ho S, Park, Sang H, Bae, Young Soo, Kwon, Byoung S

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Immunotherapy of cancer with 4-1BB von Vinay, Dass S, Kwon, Byoung S

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Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells von Lee, Seung-Woo, Croft, Michael, So, Takanori, Cheroutre, Hilde, Mittler, Robert S, Kwon, Byoung S, Park, Yunji

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4-1BB Functions As a Survival Factor in Dendritic Cells von Choi, Beom K, Kim, Young H, Kwon, Patrick M, Lee, Sang C, Kang, Sang W, Kim, Moon S, Lee, Myoung J, Kwon, Byoung S

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Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice von Lin, Gloria H Y, Liu, Yuanqing, Ambagala, Thanuja, Kwon, Byoung S, Ohashi, Pamela S, Watts, Tania H

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Immune evasion in cancer: Mechanistic basis and therapeutic strategies von Vinay, Dass S, Ryan, Elizabeth P, Pawelec, Graham, Talib, Wamidh H, Stagg, John, Elkord, Eyad, Lichtor, Terry, Decker, William K, Whelan, Richard L, Kumara, H.M.C. Shantha, Signori, Emanuela, Honoki, Kanya, Georgakilas, Alexandros G, Amin, Amr, Helferich, William G, Boosani, Chandra S, Guha, Gunjan, Ciriolo, Maria Rosa, Chen, Sophie, Mohammed, Sulma I, Azmi, Asfar S, Keith, W. Nicol, Bilsland, Alan, Bhakta, Dipita, Halicka, Dorota, Fujii, Hiromasa, Aquilano, Katia, Ashraf, S. Salman, Nowsheen, Somaira, Yang, Xujuan, Choi, Beom K, Kwon, Byoung S

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The Structure of the Trimer of Human 4-1BB Ligand Is Unique among Members of the Tumor Necrosis Factor Superfamily von Won, Eun-Young, Cha, Kiweon, Byun, Jung-Sue, Kim, Dong-Uk, Shin, Sumi, Ahn, Byungchan, Kim, Young Ho, Rice, Amanda J., Walz, Thomas, Kwon, Byoung S., Cho, Hyun-Soo

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IL7-Fc Enhances the Efficacy of Adoptive T Cell Therapy under Lymphopenic Conditions in a Murine Melanoma Model von Yu, Eun M, Cho, Eunjung, Singh, Rohit, Kim, Seon-Hee, Han, Chungyong, Han, Seongeun, Lee, Don G, Kim, Young H, Kwon, Byoung S, Choi, Beom K

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4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy von Vinay, Dass S, Kwon, Byoung S

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Exposure of a distinct PDCA-1+ (CD317) B cell population to agonistic anti-4-1BB (CD137) inhibits T and B cell responses both in vitro and in vivo von Vinay, Dass S, Lee, Seung J, Kim, Chang H, Oh, Ho Sik, Kwon, Byoung S

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