The relationship between the chemistry and biological activity of the bisphosphonates von Ebetino, Frank H, Hogan, Anne-Marie L, Sun, Shuting, Tsoumpra, Maria K, Duan, Xuchen, Triffitt, James T, Kwaasi, Aaron A, Dunford, James E, Barnett, Bobby L, Oppermann, Udo, Lundy, Mark W, Boyde, Alan, Kashemirov, Boris A, McKenna, Charles E, Russell, R. Graham G

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The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1‐Fluoro‐2‐(Imidazo‐[1,2‐α]Pyridin‐3‐yl)‐Ethyl‐Bisphosphonate) von Lawson, Michelle A, Ebetino, Frank H, Mazur, Adam, Chantry, Andrew D, Paton‐Hough, Julia, Evans, Holly R, Lath, Darren, Tsoumpra, Maria K, Lundy, Mark W, Dobson, Roy LM, Quijano, Michael, Kwaasi, Aaron A, Dunford, James E, Duan, Xuchen, Triffitt, James T, Jeans, Gwyn, Russell, R Graham G

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RAGE-mediated neutrophil dysfunction is evoked by advanced glycation end products (AGEs) von Collison, Kate S., Parhar, Ranjit S., Saleh, Soad S., Meyer, Brian F., Kwaasi, Aaron A., Hammami, Muhammad M., Schmidt, Ann Marie, Stern, David M., Al‐Mohanna, Futwan A.

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The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using en... von Tsoumpra, Maria K, Muniz, Joao R, Barnett, Bobby L, Kwaasi, Aaron A, Pilka, Ewa S, Kavanagh, Kathryn L, Evdokimov, Artem, Walter, Richard L, Von Delft, Frank, Ebetino, Frank H, Oppermann, Udo, Russell, R. Graham G, Dunford, James E

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Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Syntha... von Dunford, James E, Kwaasi, Aaron A, Rogers, Michael J, Barnett, Bobby L, Ebetino, Frank H, Russell, R. Graham G, Oppermann, Udo, Kavanagh, Kathryn L

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The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates von Dunford, James E, Pilka, Ewa, Kwaasi, Aaron A, Evdokimov, Artem, Barnett, Bobby L, Oppermann, Udo, Ebetino, Frank H, Russell, R. Graham G, Kavanagh, Kathryn L

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Structure activity relationships of nitrogen containing bisphosphonates which induce conformational changes in farnesyl pyrophosphate synthase von Dunford, James E, Kwaasi, Aaron A, Kavanagh, Kathryn L, Rogers, Michael J, Oppermann, Udo, Barnett, Bobby B, Ebetino, Frank H, Graham, R, Russell, G

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425 In-vitro regulation of immune cell functions by human IgE von Parhar, Ranjit S., Ernst, Peter, Al-Mohanna, Futwan, Kwaasi, Aaron A., Sheth, Kirtikant, Al-Humaidan, Eyad, Harfi, Harb, Al-Sedairy, Sultan

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Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy von Russell, R Graham G, Xia, Zhidao, Dunford, James E, Oppermann, Udo, Kwaasi, Aaron, Hulley, Philippa A, Kavanagh, Kathryn L, Triffitt, James T, Lundy, Mark W, Phipps, Roger J, Barnett, Bobby L, Coxon, Fraser P, Rogers, Michael J, Watts, Nelson B, Ebetino, Frank H

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Recombinant Activated Protein C Attenuates Endothelial Injury and Inhibits Procoagulant Microparticles Release in Baboon Heatstroke von Bouchama, Abderrezak, Kunzelmann, Corinne, Dehbi, Mohammed, Kwaasi, Aaron, Eldali, Abdelmoneim, Zobairi, Fatiha, Freyssinet, Jean-Marie, de Prost, Dominique

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Hsp-72, a candidate prognostic indicator of heatstroke von Dehbi, Mohammed, Baturcam, Engin, Eldali, Abdelmoneim, Ahmed, Maqbool, Kwaasi, Aaron, Chishti, Muhammad Azhar, Bouchama, Abderrezak

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Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ-T Lymphocytes-Mediated Activation Mechanism von Simoni, Daniele, Gebbia, Nicola, Invidiata, Francesco Paolo, Eleopra, Marco, Marchetti, Paolo, Rondanin, Riccardo, Baruchello, Riccardo, Provera, Stefano, Marchioro, Carla, Tolomeo, Manlio, Marinelli, Luciana, Limongelli, Vittorio, Novellino, Ettore, Kwaasi, Aaron, Dunford, James, Buccheri, Simona, Caccamo, Nadia, Dieli, Francesco

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BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO von Mabilleau, Guillaume, Kwaasi, Aaron, Sabokbar, Afsie, Tsoumpra, Maria, Ebetino, Frank, Russell, Robert

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Designed mutants of human farnesyl pyrophosphate synthase (FPPS) help to characterise the interactions of nitrogen-containing bisphosphonates with Tyrosine 204 and Phenylalanine 23... von Tsoumpra, Maria, Barnett, Bobby, Kwaasi, Aaron, Walters, Rick, Ebetino, Frank, Russell, R. Graham, Oppermann, Udo, Dunford, James

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Glucocorticoids do not protect against the lethal effects of experimental heatstroke in baboons von Bouchama, Abderrezak, Kwaasi, Aaron, Dehbi, Mohammed, Al Mohanna, Falah, Eldali, Abdelmoneim, El-Sayed, Raafat, Tbakhi, Abdelghani, Alzahrani, Ali S, Roberts, And George

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Cultivar-specific IgE-epitopes in Date (Phoenix dactylifera L.) fruit allergy: Correlation of skin test reactivity and IgE-binding properties in selecting Date cultivars for allerg... von KWAASI, A. A. A, HARFI, H. A, PARHAR, R. S, COLLISON, K. S, AL-SEDAIRY, S. T, AL-MOHANNA, F. A

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Alpha-gal-independent dual recognition and activation of xenogeneic endothelial cells and human naïve natural killer cells von SHEIKH, Sajila, PARHAR, Ranjit, KWAASI, Aaron, COLLISON, Kate, YACOUB, Magdi, STERN, David, AL-MOHANNA, Futwan

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Allergy to date fruits: characterization of antigens and allergens of fruits of the date palm (Phoenix dactylifera L.) von Kwaasi, A.A.A., Parhar, R.S., Al‐Sedairy, S.T., Collison, K.S., Al‐Mohanna, F.A., Harfi, H.A., Panzani, R.C.

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Bisphosphonates von RUSSELL, R. GRAHAM G., XIA, ZHIDAO, DUNFORD, JAMES E., OPPERMANN, UDO, KWAASI, AARON, HULLEY, PHILIPPA A., KAVANAGH, KATHRYN L., TRIFFITT, JAMES T., LUNDY, MARK W., PHIPPS, ROGER J., BARNETT, BOBBY L., COXON, FRASER P., ROGERS, MICHAEL J., WATTS, NELSON B., EBETINO, FRANK H.

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CIRCULATING HSP-72 IS AN EARLY AND LONG LASTING MARKER OF HEATSTROKE SEVERITY: 192 von Bouchama, Abderrezak, Maqbool, Ahmed, Kwaasi, Aaron, Loualich, Arslan, Chishti, Mohammed, Roberts, George, Dehbi, Mohammed

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