Kinase Inhibitor Profiling Reveals Unexpected Opportunities to Inhibit Disease-Associated Mutant Kinases von Duong-Ly, Krisna C., Devarajan, Karthik, Liang, Shuguang, Horiuchi, Kurumi Y., Wang, Yuren, Ma, Haiching, Peterson, Jeffrey R.

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High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2 von Coussens, Nathan P., Kales, Stephen C., Henderson, Mark J., Lee, Olivia W., Horiuchi, Kurumi Y., Wang, Yuren, Chen, Qing, Kuznetsova, Ekaterina, Wu, Jianghong, Chakka, Sirisha, Cheff, Dorian M., Cheng, Ken Chih-Chien, Shinn, Paul, Brimacombe, Kyle R., Shen, Min, Simeonov, Anton, Lal-Nag, Madhu, Ma, Haiching, Jadhav, Ajit, Hall, Matthew D.

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Challenges in profiling and lead optimization of drug discovery for methyltransferases von Horiuchi, Kurumi Y.

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Leveraging an Open Science Drug Discovery Model to Develop CNS-Penetrant ALK2 Inhibitors for the Treatment of Diffuse Intrinsic Pontine Glioma von Smil, David, Wong, Jong Fu, Williams, Eleanor P, Adamson, Roslin J, Howarth, Alison, McLeod, David A, Mamai, Ahmed, Kim, Soyoung, Wilson, Brian J, Kiyota, Taira, Aman, Ahmed, Owen, Julie, Poda, Gennady, Horiuchi, Kurumi Y, Kuznetsova, Ekaterina, Ma, Haiching, Hamblin, J. Nicole, Cramp, Sue, Roberts, Owen G, Edwards, Aled M, Uehling, David, Al-awar, Rima, Bullock, Alex N, O’Meara, Jeff A, Isaac, Methvin B

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Chemical microarray: a new tool for drug screening and discovery von Ma, Haiching, Horiuchi, Kurumi Y.

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Assay development for histone methyltransferases von Horiuchi, Kurumi Y, Eason, Mia M, Ferry, Joseph J, Planck, Jamie L, Walsh, Colin P, Smith, Robert F, Howitz, Konrad T, Ma, Haiching

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Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase von Favata, M F, Horiuchi, K Y, Manos, E J, Daulerio, A J, Stradley, D A, Feeser, W S, Van Dyk, D E, Pitts, W J, Earl, R A, Hobbs, F, Copeland, R A, Magolda, R L, Scherle, P A, Trzaskos, J M

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Development and Use of Assay Conditions Suited to Screening for and Profiling of SET-Domain-Targeted Inhibitors of the MLL/SET1 Family of Lysine Methyltransferases von Ferry, Joseph J, Smith, Robert F, Denney, Natalie, Walsh, Colin P, McCauley, Lauren, Qian, Jie, Ma, Haiching, Horiuchi, Kurumi Y, Howitz, Konrad T

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295 Feasibility Examination of Prior Administration of Cyclophosphamide in TC Combination von Abe, H, Kawai, Y, Mori, T, Cho, H, Kubota, Y, Umeda, T, Kurumi, Y, Tani, T

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Microarrays for the Functional Analysis of the Chemical-Kinase Interactome von Horiuchi, Kurumi Y., Wang, Yuan, Diamond, Scott L., Ma, Haiching

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Fluorescence Polarization and Time-Resolved Fluorescence Resonance Energy Transfer Techniques for PI3K Assays von Horiuchi, Kurumi Y., Ma, Haiching

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Nanoliter homogenous ultra-high throughput screening microarray for lead discoveries and IC50 profiling von Ma, Haiching, Horiuchi, Kurumi Y, Wang, Yuan, Kucharewicz, Stefan A, Diamond, Scott L

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Beyond U0126. Dianion chemistry leading to the rapid synthesis of a series of potent MEK inhibitors von Wityak, John, Hobbs, Frank W., Gardner, Daniel S., Santella, Joseph B., Petraitis, Joseph J., Sun, Jung-Hui, Favata, Margaret F., Daulerio, Andrea J., Horiuchi, Kurumi Y., Copeland, Robert A., Scherle, Peggy A., Jaffe, Bruce D., Trzaskos, James M., Magolda, Ronald L., Trainor, George L., Duncia, John V.

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Abstract 170: Development of diacylglycerol kinase assays to facilitate isoform specific inhibitor discovery von AbdulSalam, Safnas F., Eason, Mia M., Fowle, Holly A., Stuart, Anna L., Horiuchi, Kurumi Y.

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Biochemical microarrays for studying chemical biology interaction: DiscoveryDot technology von Horiuchi, Kurumi Y, Wang, Yuan, Ma, Haiching

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PP009-SUN RESTING ENERGY EXPENDITURE IN PATIENTS UNDERGOING PYLORUS PRESERVING PANCREATODUODENECTOMIES FOR BILE DUCT CANCER OR PANCREATIC TUMORS von Okamoto, H, Sasaki, M, Kurihara, M, Iwakawa, H, Shiomi, H, Naka, S, Kurumi, Y, Terada, T

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Chemical Microarrays: A New Tool for Discovery Enzyme Inhibitors von Liang, Shuguang, Xu, Wei, Horiuchi, Kurumi Y., Wang, Yuan, Ma, Haiching

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Fluorescence navigation system with indocyanine green for sentinel lymph nodes biopsy in breast cancer patients von Abe, H, Shimizu, T, Cho, H, Murata, S, Kurumi, Y, Tani, T

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Mutagenesis and Mechanism-Based Inhibition of Streptococcus pyogenes Glu-tRNAGln Amidotransferase Implicate a Serine-Based Glutaminase Site von Harpel, Mark R, Horiuchi, Kurumi Y, Luo, Ying, Shen, Li, Jiang, Wenjun, Nelson, David J, Rogers, Kelley C, Decicco, Carl P, Copeland, Robert A

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HotSpot: A Novel Methyltransferase Assay Platform for Drug Screening and Discovery von Horiuchi, Kurumi Y, Eason, Mia M, Ma, Haiching

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