PP 7.12 – 00192 The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection von Sykulev, Y., Anikeeva, N., Steblyanko, M., Kuri-Cervantes, L., Buggert, M., Betts, M.R.

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Intact and replication-competent reservoir virus populations differ from each other and rebound plasma viruses von Bar, K., Mampe, F., Monroy, M.A., Lindemuth, E., Kuri Cervantes, L., Bibollet-Ruche, F., Hahn, B., Salantes, D.B.

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Baseline inducible HIV P24 is associated with viral control during interferon-α monotherapy with ART interruption von Montaner, L.J., Azzoni, L., Papasavvas, E., Tebas, P., Mounzer, K., Howell, B., Holder, D., Chomont, N., Kuri Cervantes, L., Betts, M.

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Novel SHIVs encoding transmitted/founder Envs for latency and cure research von Bauer, A., Lindemuth, E., Kuri-Cervantes, L., Li, H., Watkins, M., Ziani, W., Xu, H., Veazey, R., Shaw, G., Bar, K.

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Peripheral blood SIV/HIV originates from infected cells in tissues von Betts, M., Kuri Cervantes, L., Pampena, M.B., Samer, S., Khoury, D., Frank, I., Paiardini, M., Davenport, M., Bar, K., Veazey, R.

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T follicular helper cells in human efferent lymph retain lymphoid characteristics von Vella, Laura A, Buggert, Marcus, Manne, Sasikanth, Herati, Ramin S, Sayin, Ismail, Kuri-Cervantes, Leticia, Bukh Brody, Irene, O'Boyle, Kaitlin C, Kaprielian, Hagop, Giles, Josephine R, Nguyen, Son, Muselman, Alexander, Antel, Jack P, Bar-Or, Amit, Johnson, Matthew E, Canaday, David H, Naji, Ali, Ganusov, Vitaly V, Laufer, Terri M, Wells, Andrew D, Dori, Yoav, Itkin, Maxim G, Betts, Michael R, Wherry, E John

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CD32+ CD4+ T Cells are HIV transcriptionally active rather than a resting reservoir von Abdel-Mohsen, M., Tomescu, C., Vadrevu, S., Spivak, A., Kuri-Cervantes, L., Wu, G., Cox, K., Vemula, S., Fair, M., Lynn, K., Buzon, M.J., Martinez-Picado, J., Betts, M., Planelles, V., Mounzer, K., Howell, B., Hazuda, D., Tebas, P., Montaner, L.J.

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The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection von Anikeeva, Nadia, Steblyanko, Maria, Kuri-Cervantes, Leticia, Buggert, Marcus, Betts, Michael R., Sykulev, Yuri

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The Identity of Human Tissue-Emigrant CD8+ T Cells von Buggert, Marcus, Vella, Laura A., Nguyen, Son, Wu, Vincent H., Chen, Zeyu, Sekine, Takuya, Perez-Potti, André, Maldini, Colby R., Manne, Sasikanth, Darko, Samuel, Ransier, Amy, Kuri-Cervantes, Leticia, Japp, Alberto Sada, Brody, Irene Bukh, Ivarsson, Martin A., Gorin, Jean-Baptiste, Rivera-Ballesteros, Olga, Hertwig, Laura, Antel, Jack P., Johnson, Matthew E., Okoye, Afam, Picker, Louis, Vahedi, Golnaz, Sparrelid, Ernesto, Llewellyn-Lacey, Sian, Gostick, Emma, Sandberg, Johan K., Björkström, Niklas, Bar-Or, Amit, Dori, Yoav, Naji, Ali, Canaday, David H., Laufer, Terri M., Wells, Andrew D., Price, David A., Frank, Ian, Douek, Daniel C., Wherry, E. John, Itkin, Maxim G., Betts, Michael R.

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Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells von Nguyen, S, Deleage, C, Darko, S, Ransier, A, Truong, DP, Agarwal, D, Japp, AS, Wu, VH, Kuri-Cervantes, L, Abdel-Mohsen, M, Estrada, PMD, Ablanedo-Terrazas, Y, Gostick, E, Hoxie, JA, Zhang, NR, Naji, A, Reyes-Teran, G, Estes, JD, Price, DA, Douek, DC, Deeks, SG, Buggert, M, Betts, MR

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Analysis of the structure and dynamics of synaptic interface revealed functional anomaly of naive CD8+ T cells during HIV infection von Anikeeva, Nadia, Steblyanko, Maria, Kuri-Cervantes, Leticia, Buggert, Marcus, Betts, Michael, Sykulev, Yuri

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HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue von Reuter, Morgan A., Del Rio Estrada, Perla M., Buggert, Marcus, Petrovas, Constantinos, Ferrando-Martinez, Sara, Nguyen, Son, Sada Japp, Alberto, Ablanedo-Terrazas, Yuria, Rivero-Arrieta, Amaranta, Kuri-Cervantes, Leticia, Gunzelman, Heidi M., Gostick, Emma, Price, David A., Koup, Richard A., Naji, Ali, Canaday, David H., Reyes-Terán, Gustavo, Betts, Michael R.

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NKG2C super(+) NK Cells Contribute to Increases in CD16 super(+)CD56 super(-) Cells in HIV Type 1 super(+) Individuals with High Plasma Viral Load von Gregson, JNS, Kuri-Cervantes, L, Mela, C M, Gazzard, B G, Bower, M, Goodier, M R

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PD-1 Expression on Natural Killer Cells and CD8 super(+) T Cells During Chronic HIV-1 Infection von Norris, S, Coleman, A, Kuri-Cervantes, L, Bower, M, Nelson, M, Goodier, M R

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Erythrocytes identify complement activation in patients with COVID-19 von Lam, L K Metthew, Reilly, John P, Rux, Ann H, Murphy, Sophia J, Kuri-Cervantes, Leticia, Weisman, Ariel R, Ittner, Caroline A G, Pampena, M Betina, Betts, Michael R, Wherry, E John, Song, Wen-Chao, Lambris, John D, Meyer, Nuala J, Cines, Douglas B, Mangalmurti, Nilam S

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Recyclable and Photocatalytic Properties of ZnFe2O4/ZnO for Wastewater Treatment and Disinfection von Maynez‐Navarro, Oscar D., Mendez‐Rojas, Miguel A., Flores‐Cervantes, Deborah X., Kuri, Ulises Salazar, Sanchez‐Salas, Jose L.

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Assessment of HIV-1 integration in tissues and subsets across infection stages von Wu, Vincent H, Nobles, Christopher L, Kuri-Cervantes, Leticia, McCormick, Kevin, Everett, John K, Nguyen, Son, Del Rio Estrada, Perla M, González-Navarro, Mauricio, Torres-Ruiz, Fernanda, Ávila-Ríos, Santiago, Reyes-Terán, Gustavo, Bushman, Frederic D, Betts, Michael R

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Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue von Buggert, M, Nguyen, S, de Oca, GSM, Bengsch, B, Darko, S, Ransier, A, Roberts, ER, del Alcazar, D, Brody, IB, Vella, LA, Beura, L, Wijeyesinghe, S, Herati, RS, Estrada, PMD, Ablanedo-Terrazas, Y, Kuri-Cervantes, L, Japp, AS, Manne, S, Vartanian, S, Huffman, A, Sandberg, JK, Gostick, E, Nadolski, G, Silvestri, G, Canaday, DH, Price, DA, Petrovas, C, Su, LF, Vahedi, G, Dori, Y, Frank, I, Itkin, MG, Wherry, EJ, Deeks, SG, Naji, A, Reyes-Teran, G, Masopust, D, Douek, DC, Betts, MR

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AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver von Greig, Jenny A, Calcedo, Roberto, Kuri-Cervantes, Leticia, Nordin, Jayme M L, Albrecht, Jessica, Bote, Erin, Goode, Tamara, Chroscinski, Edward A, Bell, Peter, Richman, Laura K, Betts, Michael R, Wilson, James M

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P6257Blood pressure and death from vascular and metabolic diseases in Mexico City: 12-year follow-up of 150,000 adults von Alegre-Diaz, J., Gnatiuc, L., Wade, R., Ramirez, R., Herrington, W.G., Lewington, S.L., Lopez Cervantes, M., Solano, M., Peto, R., Collins, R., Tapia-Conyer, R., Kuri-Morales, P., Emberson, J.R.

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