Single-cell transcriptional diversity is a hallmark of developmental potential von Gulati, Gunsagar S., Sikandar, Shaheen S., Wesche, Daniel J., Manjunath, Anoop, Bharadwaj, Anjan, Berger, Mark J., Ilagan, Francisco, Kuo, Angera H., Hsieh, Robert W., Cai, Shang, Zabala, Maider, Scheeren, Ferenc A., Lobo, Neethan A., Qian, Dalong, Yu, Feiqiao B., Dirbas, Frederick M., Clarke, Michael F., Newman, Aaron M.

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A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer von Betancur, Paola A., Abraham, Brian J., Yiu, Ying Y., Willingham, Stephen B., Khameneh, Farnaz, Zarnegar, Mark, Kuo, Angera H., McKenna, Kelly, Kojima, Yoko, Leeper, Nicholas J., Ho, Po, Gip, Phung, Swigut, Tomek, Sherwood, Richard I., Clarke, Michael F., Somlo, George, Young, Richard A., Weissman, Irving L.

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Targeting Unique Metabolic Properties of Breast Tumor Initiating Cells von Feng, Weiguo, Gentles, Andrew, Nair, Ramesh V., Huang, Min, Lin, Yuan, Lee, Cleo Y., Cai, Shang, Scheeren, Ferenc A., Kuo, Angera H., Diehn, Maximilian

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Role of epithelial to mesenchymal transition associated genes in mammary gland regeneration and breast tumorigenesis von Sikandar, Shaheen S., Kuo, Angera H., Kalisky, Tomer, Cai, Shang, Zabala, Maider, Hsieh, Robert W., Lobo, Neethan A., Scheeren, Ferenc A., Sim, Sopheak, Qian, Dalong, Dirbas, Frederick M., Somlo, George, Quake, Stephen R., Clarke, Michael F.

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A cell-intrinsic role for TLR2–MYD88 in intestinal and breast epithelia and oncogenesis von Scheeren, Ferenc A., Kuo, Angera H., van Weele, Linda J., Cai, Shang, Glykofridis, Iris, Sikandar, Shaheen S., Zabala, Maider, Qian, Dalong, Lam, Jessica S., Johnston, Darius, Volkmer, Jens P., Sahoo, Debashis, van de Rijn, Matt, Dirbas, Frederick M., Somlo, George, Kalisky, Tomer, Rothenberg, Michael E., Quake, Stephen R., Clarke, Michael F.

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miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway von Isobe, Taichi, Hisamori, Shigeo, Hogan, Daniel J, Zabala, Maider, Hendrickson, David G, Dalerba, Piero, Cai, Shang, Scheeren, Ferenc, Kuo, Angera H, Sikandar, Shaheen S, Lam, Jessica S, Qian, Dalong, Dirbas, Frederick M, Somlo, George, Lao, Kaiqin, Brown, Patrick O, Clarke, Michael F, Shimono, Yohei

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Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib von Padera, Timothy P, Kuo, Angera H, Hoshida, Tohru, Liao, Shan, Lobo, Jennifer, Kozak, Kevin R, Fukumura, Dai, Jain, Rakesh K

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A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland von Cai, Shang, Kalisky, Tomer, Sahoo, Debashis, Dalerba, Piero, Feng, Weiguo, Lin, Yuan, Qian, Dalong, Kong, Angela, Yu, Jeffrey, Wang, Flora, Chen, Elizabeth Y., Scheeren, Ferenc A., Kuo, Angera H., Sikandar, Shaheen S., Hisamori, Shigeo, van Weele, Linda J., Heiser, Diane, Sim, Sopheak, Lam, Jessica, Quake, Stephen, Clarke, Michael F.

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LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis von Zabala, Maider, Lobo, Neethan A., Antony, Jane, Heitink, Luuk S., Gulati, Gunsagar S., Lam, Jessica, Parashurama, Natesh, Sanchez, Kassandra, Adorno, Maddalena, Sikandar, Shaheen S., Kuo, Angera H., Qian, Dalong, Kalisky, Tomer, Sim, Sopheak, Li, Linus, Dirbas, Frederick M., Somlo, George, Newman, Aaron, Quake, Stephen R., Clarke, Michael F.

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Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon von TASSI, Elena, HENKE, Ralf T, BOWDEN, Emma T, SWIFT, Matthew R, KODACK, David P, KUO, Angera H, MAITRA, Anirban, WELLSTEIN, Anton

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Cell-intrinsic TLR2/MyD88 pathway in breast and colon cancer von Kuo, Angera H, Scheeren, Ferenc A

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Identifying the metastatic seeds of breast cancer von Kuo, Angera H, Clarke, Michael F

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Depletion of Trp53 and Cdkn2a Does Not Promote Self-Renewal in the Mammary Gland but Amplifies Proliferation Induced by TNF-α von van Weele, Linda J., Scheeren, Ferenc A., Cai, Shang, Kuo, Angera H., Qian, Dalong, Ho, William H.D., Clarke, Michael F.

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Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation von LEE, Cleo Yi-Fang, YUAN LIN, BRATMAN, Scott V, WEIGUO FENG, KUO, Angera H, SCHEEREN, Ferenc A, ENGREITZ, Jesse M, VARMA, Sushama, WEST, Robert B, DIEHN, Maximilian

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Structure-Based Approach for the Discovery of Bis-benzamidines as Novel Inhibitors of Matriptase von Enyedy, Istvan J, Lee, Sheau-Ling, Kuo, Angera H, Dickson, Robert B, Lin, Chen-Yong, Wang, Shaomeng

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Cardiac and inflammatory biomarkers do not correlate with volume of heart or lung receiving radiation von Kuo, Angera H, Ancukiewicz, Marek, Kozak, Kevin R, Yock, Torunn I, Padera, Timothy P

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Identification of a minority population of LMO2 + breast cancer cells that integrate into the vasculature and initiate metastasis von Sikandar, Shaheen S, Gulati, Gunsagar S, Antony, Jane, Fetter, Isobel, Kuo, Angera H, Ho, William Hai Dang, Haro-Acosta, Veronica, Das, Soumyashree, Steen, Chloé B, Pereira, Thiago Almeida, Qian, Dalong, Beachy, Philip A, Dirbas, Frederick M, Red-Horse, Kristy, Rabbitts, Terence H, Thiery, Jean Paul, Newman, Aaron M, Clarke, Michael F

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Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells von Kesler, Cristina T., Kuo, Angera H., Wong, Hon-Kit, Masuck, David J., Shah, Jennifer L., Kozak, Kevin R., Held, Kathryn D., Padera, Timothy P.

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Identifying the metastatic seeds of breast cancer: two studies show that circulating tumor cells from breast cancer patients give rise to metastases in mice von Kuo, Angera H, Clarke, Michael F

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Abstract B67: The DLK1-DIO3 imprinted region regulates long-term proliferation in normal and malignant breast epithelium von Zabala, Maider, Lobo, Neethan A., Seoane, Jose A., Stelzer, Yonatan, Luong, An V., Isobe, Taichi, Zarnegar, Mark A., Watanabe, Nicholas, Antoñana, Sonia, Lam, Jessica, Qian, Dalong, Sikandar, Shaheen S., Kuo, Angera H., Heitink, Luuk S., Shimono, Yohei, Scheeren, Ferenc A., Cai, Shang, Hisamori, Shigeo, Sahoo, Debashis, Dirbas, Frederick M., Somlo, George, Jaenisch, Rudolf, Christina, Curtis, Clarke, Michael F.

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