Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake von Green, Charlotte J., Göransson, Olga, Kular, Gursant S., Leslie, Nick R., Gray, Alexander, Alessi, Dario R., Sakamoto, Kei, Hundal, Harinder S.

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Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1 von Fleming, Ian N, Batty, Ian H, Prescott, Alan R, Gray, Alex, Kular, Gursant S, Stewart, Hazel, Downes, C Peter

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FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P von Matteis, M. Antonietta De, Godi, Anna, Campli, Antonella Di, Konstantakopoulos, Athanasios, Tullio, Giuseppe Di, Alessi, Dario R, Kular, Gursant S, Daniele, Tiziana, Marra, Pierfrancesco, Lucocq, John M

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Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates von Komander, David, Fairservice, Alison, Deak, Maria, Kular, Gursant S, Prescott, Alan R, Peter Downes, C, Safrany, Stephen T, Alessi, Dario R, van Aalten, Daan MF

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Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition von Komander, David, Kular, Gursant S, Bain, Jennifer, Elliott, Matthew, Alessi, Dario R, Van Aalten, Daan M F

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Interactions of LY333531 and Other Bisindolyl Maleimide Inhibitors with PDK1 von Komander, David, Kular, Gursant S., Schüttelkopf, Alexander W., Deak, Maria, Prakash, K.R.C., Bain, Jennifer, Elliott, Matthew, Garrido-Franco, Marta, Kozikowski, Alan P., Alessi, Dario R., van Aalten, Daan M.F.

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FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdInsP von Godi, Anna, Campli, Antonella Di, Konstantakopoulos, Athanasios, Tullio, Giuseppe Di, Alessi, Dario R, Kular, Gursant S, Daniele, Tiziana, Marra, Pierfrancesco, Lucocq, John M, Matteis, M. Antonietta De

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Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro von Kular, Gursant S, Chaudhary, Anu, Prestwich, Glenn, Swigart, Philip, Wetzker, Reinhard, Cockcroft, Shamshad

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Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism von Powell, Darren J., Hajduch, Eric, Kular, Gursant, Hundal, Harinder S.

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Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C δ1 von WATT, Stephen A., KULAR, Gursant, FLEMING, Ian N., DOWNES, C. Peter, LUCOCQ, John M.

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Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities von Dowler, S, Currie, R A, Campbell, D G, Deak, M, Kular, G, Downes, C P, Alessi, D R

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TAK1-binding protein 1 is a pseudophosphatase von Conner, Sarah H, Kular, Gursant, Peggie, Mark, Shepherd, Sharon, Schüttelkopf, Alexander W, Cohen, Philip, Van Aalten, Daan M F

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Role of T-loop Phosphorylation in PDK1 Activation, Stability, and Substrate Binding von Komander, David, Kular, Gursant, Deak, Maria, Alessi, Dario R., van Aalten, Daan M.F.

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Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism von Powell, Darren J, Hajduch, Eric, Kular, Gursant, Hundal, Harinder S

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Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in the formylmethionyl-leucylphenylalanine-dependent production of phosphatidylinositol 3... von Kular, G, Loubtchenkov, M, Swigart, P, Whatmore, J, Ball, A, Cockcroft, S, Wetzker, R

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Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C δ1 von WATT, Stephen A., KULAR, Gursant, FLEMING, Ian N., DOWNES, C. Peter, LUCOCQ, John M.

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Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1 von Watt, Stephen A, Kular, Gursant, Fleming, Ian N, Downes, C Peter, Lucocq, John M

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Protein lipid overlay assay von Dowler, Simon, Kular, Gursant, Alessi, Dario R

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Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities von DOWLER, Simon, CURRIE, Richard A., CAMPBELL, David G., DEAK, Maria, KULAR, Gursant, DOWNES, C. Peter, ALESSI, Dario R.

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