Diagnostic Testing for Chronic Granulomatous Disease von Kuhns, Douglas B.

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Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels von Davies, Luke C., Rice, Christopher M., Palmieri, Erika M., Taylor, Philip R., Kuhns, Douglas B., McVicar, Daniel W.

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A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency von Zhou, Qing, Lee, Geun-Shik, Brady, Jillian, Datta, Shrimati, Katan, Matilda, Sheikh, Afzal, Martins, Marta S, Bunney, Tom D, Santich, Brian H, Moir, Susan, Kuhns, Douglas B, Long Priel, Debra A, Ombrello, Amanda, Stone, Deborah, Ombrello, Michael J, Khan, Javed, Milner, Joshua D, Kastner, Daniel L, Aksentijevich, Ivona

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HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease von Cook, Sarah A., Comrie, William A., Poli, M. Cecilia, Similuk, Morgan, Oler, Andrew J., Faruqi, Aiman J., Kuhns, Douglas B., Yang, Sheng, Vargas-Hernandez, Alexander, Carisey, Alexandre F., Fournier, Benjamin, Anderson, D. Eric, Price, Susan, Smelkinson, Margery, Abou Chahla, Wadih, Forbes, Lisa R., Mace, Emily M., Cao, Tram N., Coban-Akdemir, Zeynep H., Jhangiani, Shalini N., Muzny, Donna M., Gibbs, Richard A., Lupski, James R., Orange, Jordan S., Cuvelier, Geoffrey D. E., Al Hassani, Moza, Al Kaabi, Nawal, Al Yafei, Zain, Jyonouchi, Soma, Raje, Nikita, Caldwell, Jason W., Huang, Yanping, Burkhardt, Janis K., Latour, Sylvain, Chen, Baoyu, ElGhazali, Gehad, Rao, V. Koneti, Chinn, Ivan K., Lenardo, Michael J.

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Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19 von Sacco, Keith, Castagnoli, Riccardo, Vakkilainen, Svetlana, Liu, Can, Delmonte, Ottavia M., Oguz, Cihan, Kaplan, Ian M., Alehashemi, Sara, Burbelo, Peter D., Bhuyan, Farzana, de Jesus, Adriana A., Dobbs, Kerry, Rosen, Lindsey B., Cheng, Aristine, Shaw, Elana, Vakkilainen, Mikko S., Pala, Francesca, Lack, Justin, Zhang, Yu, Fink, Danielle L., Oikonomou, Vasileios, Snow, Andrew L., Dalgard, Clifton L., Chen, Jinguo, Sellers, Brian A., Montealegre Sanchez, Gina A., Barron, Karyl, Rey-Jurado, Emma, Vial, Cecilia, Poli, Maria Cecilia, Licari, Amelia, Montagna, Daniela, Marseglia, Gian Luigi, Licciardi, Francesco, Ramenghi, Ugo, Discepolo, Valentina, Lo Vecchio, Andrea, Guarino, Alfredo, Eisenstein, Eli M., Imberti, Luisa, Sottini, Alessandra, Biondi, Andrea, Mató, Sayonara, Gerstbacher, Dana, Truong, Meng, Stack, Michael A., Magliocco, Mary, Bosticardo, Marita, Kawai, Tomoki, Danielson, Jeffrey J., Hulett, Tyler, Askenazi, Manor, Hu, Shaohui, Cohen, Jeffrey I., Su, Helen C., Kuhns, Douglas B., Lionakis, Michail S., Snyder, Thomas M., Holland, Steven M., Goldbach-Mansky, Raphaela, Tsang, John S., Notarangelo, Luigi D.

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X-linked Carriers of Chronic Granulomatous Disease: Illness, Lyonization and Stability von Marciano, Beatriz E., MD, Zerbe, Christa S., MD, Falcone, E. Liana, MD PhD, Ding, Li, MD, DeRavin, Suk See, MD PhD, Daub, Janine, CRNP, Kreuzburg, Samantha, CRNP, Yockey, Lynne, CRNP, Hunsberger, Sally, PHD, Foruraghi, Ladan, CRNP, Barnhart, Lisa A., CRNP, Matharu, Kabir, MD, Anderson, Victoria, CRNP, Darnell, Dirk N., CRNP, Frein, Cathleen, CRNP, Fink, Danielle L., MS, Lau, Karen P., MS, Long Priel, Debra A., MS, Gallin, John I., MD, Malech, Harry L., MD, Uzel, Gulbu, MD, Freeman, Alexandra F., MD, Kuhns, Douglas B., PhD, Rosenzweig, Sergio D., MD PhD, Holland, Steven M., MD

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Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia von Kim, Miriam Y., Yu, Kyung-Rok, Kenderian, Saad S., Ruella, Marco, Chen, Shirley, Shin, Tae-Hoon, Aljanahi, Aisha A., Schreeder, Daniel, Klichinsky, Michael, Shestova, Olga, Kozlowski, Miroslaw S., Cummins, Katherine D., Shan, Xinhe, Shestov, Maksim, Bagg, Adam, Morrissette, Jennifer J.D., Sekhri, Palak, Lazzarotto, Cicera R., Calvo, Katherine R., Kuhns, Douglas B., Donahue, Robert E., Behbehani, Gregory K., Tsai, Shengdar Q., Dunbar, Cynthia E., Gill, Saar

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Chromothriptic Cure of WHIM Syndrome von McDermott, David H., Gao, Ji-Liang, Liu, Qian, Siwicki, Marie, Martens, Craig, Jacobs, Paejonette, Velez, Daniel, Yim, Erin, Bryke, Christine R., Hsu, Nancy, Dai, Zunyan, Marquesen, Martha M., Stregevsky, Elina, Kwatemaa, Nana, Theobald, Narda, Long Priel, Debra A., Pittaluga, Stefania, Raffeld, Mark A., Calvo, Katherine R., Maric, Irina, Desmond, Ronan, Holmes, Kevin L., Kuhns, Douglas B., Balabanian, Karl, Bachelerie, Françoise, Porcella, Stephen F., Malech, Harry L., Murphy, Philip M.

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Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19 von Liu, Can, Martins, Andrew J., Lau, William W., Rachmaninoff, Nicholas, Chen, Jinguo, Imberti, Luisa, Mostaghimi, Darius, Fink, Danielle L., Burbelo, Peter D., Dobbs, Kerry, Delmonte, Ottavia M., Bansal, Neha, Failla, Laura, Sottini, Alessandra, Quiros-Roldan, Eugenia, Han, Kyu Lee, Sellers, Brian A., Cheung, Foo, Sparks, Rachel, Chun, Tae-Wook, Moir, Susan, Lionakis, Michail S., Abers, Michael S., Apps, Richard, Bosticardo, Marita, Milanez-Almeida, Pedro, Mulè, Matthew P., Shaw, Elana, Zhang, Yu, Castelli, Francesco, Muiesan, Maria Lorenza, Tomasoni, Gabriele, Scolari, Francesco, Tucci, Alessandra, Rossi, Camillo, Su, Helen C., Kuhns, Douglas B., Cohen, Jeffrey I., Notarangelo, Luigi D., Tsang, John S.

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Lentiviral gene therapy for X-linked chronic granulomatous disease von Kohn, Donald B., Booth, Claire, Kang, Elizabeth M., Pai, Sung-Yun, Shaw, Kit L., Santilli, Giorgia, Armant, Myriam, Buckland, Karen F., Choi, Uimook, De Ravin, Suk See, Dorsey, Morna J., Kuo, Caroline Y., Leon-Rico, Diego, Rivat, Christine, Izotova, Natalia, Gilmour, Kimberly, Snell, Katie, Dip, Jinhua Xu-Bayford, Darwish, Jinan, Morris, Emma C., Terrazas, Dayna, Wang, Leo D., Bauser, Christopher A., Paprotka, Tobias, Kuhns, Douglas B., Gregg, John, Raymond, Hayley E., Everett, John K., Honnet, Geraldine, Biasco, Luca, Newburger, Peter E., Bushman, Frederic D., Grez, Manuel, Gaspar, H. Bobby, Williams, David A., Malech, Harry L., Galy, Anne, Thrasher, Adrian J.

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Signal transducer and activator of transcription 1 ( STAT1 ) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis von Sampaio, Elizabeth P., MD, PhD, Hsu, Amy P., BA, Pechacek, Joseph, BA, Bax, Hannelore I., MD, Dias, Dalton L., BA, Paulson, Michelle L., MD, Chandrasekaran, Prabha, PhD, Rosen, Lindsey B., BS, Carvalho, Daniel S., PhD, Ding, Li, MD, Vinh, Donald C., MD, Browne, Sarah K., MD, Datta, Shrimati, PhD, Milner, Joshua D., MD, Kuhns, Douglas B., PhD, Long Priel, Debra A., BS, Sadat, Mohammed A., MD, Shiloh, Michael, MD, PhD, De Marco, Brendan, MD, Alvares, Michael, MD, Gillman, Jason W., MD, Ramarathnam, Vivek, MD, de la Morena, Maite, MD, Bezrodnik, Liliana, MD, Moreira, Ileana, MD, Uzel, Gulbu, MD, Johnson, Daniel, MD, Spalding, Christine, RN, Zerbe, Christa S., MD, Wiley, Henry, MD, Greenberg, David E., MD, Hoover, Susan E., MD, PhD, Rosenzweig, Sergio D., MD, PhD, Galgiani, John N., MD, Holland, Steven M., MD

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Isolation and Functional Analysis of Human Neutrophils von Kuhns, Douglas B., Priel, Debra A. Long, Chu, Jessica, Zarember, Kol A.

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Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology von Takeda, Andrew J., Maher, Timothy J., Zhang, Yu, Lanahan, Stephen M., Bucklin, Molly L., Compton, Susan R., Tyler, Paul M., Comrie, William A., Matsuda, Makoto, Olivier, Kenneth N., Pittaluga, Stefania, McElwee, Joshua J., Long Priel, Debra A., Kuhns, Douglas B., Williams, Roger L., Mustillo, Peter J., Wymann, Matthias P., Koneti Rao, V., Lucas, Carrie L.

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Common Severe Infections in Chronic Granulomatous Disease von Marciano, Beatriz E., Spalding, Christine, Fitzgerald, Alan, Mann, Daphne, Brown, Thomas, Osgood, Sharon, Yockey, Lynne, Darnell, Dirk N., Barnhart, Lisa, Daub, Janine, Boris, Lisa, Rump, Amy P., Anderson, Victoria L., Haney, Carissa, Kuhns, Douglas B., Rosenzweig, Sergio D., Kelly, Corin, Zelazny, Adrian, Mason, Tamika, See DeRavin, Suk, Kang, Elizabeth, Gallin, John I., Malech, Harry L., Olivier, Kenneth N., Uzel, Gulbu, Freeman, Alexandra F., Heller, Theo, Zerbe, Christa S., Holland, Steven M.

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A phase III randomized crossover trial of plerixafor versus G-CSF for treatment of WHIM syndrome von McDermott, David H, Velez, Daniel, Cho, Elena, Cowen, Edward W, DiGiovanna, John J, Pastrana, Diana V, Buck, Christopher B, Calvo, Katherine R, Gardner, Pamela J, Rosenzweig, Sergio D, Stratton, Pamela, Merideth, Melissa A, Kim, H Jeffrey, Brewer, Carmen, Katz, James D, Kuhns, Douglas B, Malech, Harry L, Follmann, Dean, Fay, Michael P, Murphy, Philip M

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An immune-based biomarker signature is associated with mortality in COVID-19 patients von Abers, Michael S., Delmonte, Ottavia M., Ricotta, Emily E., Fintzi, Jonathan, Fink, Danielle L., de Jesus, Adriana A. Almeida, Zarember, Kol A., Alehashemi, Sara, Oikonomou, Vasileios, Desai, Jigar, Canna, Scott W., Shakoory, Bita, Dobbs, Kerry, Imberti, Luisa, Sottini, Alessandra, Quiros-Roldan, Eugenia, Castelli, Francesco, Rossi, Camillo, Brugnoni, Duilio, Biondi, Andrea, Bettini, Laura Rachele, D'Angio', Mariella, Bonfanti, Paolo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Gliniewicz, Emily F., Shaw, Elana, Kahle, Dana E., Rastegar, Andre T., Stack, Michael, Myint-Hpu, Katherine, Levinson, Susan L., DiNubile, Mark J., Chertow, Daniel W., Burbelo, Peter D., Cohen, Jeffrey, Calvo, Katherine R., Tsang, John S., Su, Helen C., Gallin, John, Kuhns, Douglas B., Goldbach-Mansky, Raphaela, Lionakis, Michail S., Notarangelo, Luigi D.

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Residual NADPH Oxidase and Survival in Chronic Granulomatous Disease von Kuhns, Douglas B, Alvord, W. Gregory, Heller, Theo, Feld, Jordan J, Pike, Kristen M, Marciano, Beatriz E, Uzel, Gulbu, DeRavin, Suk See, Priel, Debra A. Long, Soule, Benjamin P, Zarember, Kol A, Malech, Harry L, Holland, Steven M, Gallin, John I

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Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells von De Ravin, Suk See, Brault, Julie, Meis, Ronald J., Liu, Siyuan, Li, Linhong, Pavel-Dinu, Mara, Lazzarotto, Cicera R., Liu, Taylor, Koontz, Sherry M., Choi, Uimook, Sweeney, Colin L., Theobald, Narda, Lee, GaHyun, Clark, Aaron B., Burkett, Sandra S., Kleinstiver, Benjamin P., Porteus, Matthew H., Tsai, Shengdar, Kuhns, Douglas B., Dahl, Gary A., Headey, Stephen, Wu, Xiaolin, Malech, Harry L.

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Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome von Hsu, Amy P., Sampaio, Elizabeth P., Khan, Javed, Calvo, Katherine R., Lemieux, Jacob E., Patel, Smita Y., Frucht, David M., Vinh, Donald C., Auth, Roger D., Freeman, Alexandra F., Olivier, Kenneth N., Uzel, Gulbu, Zerbe, Christa S., Spalding, Christine, Pittaluga, Stefania, Raffeld, Mark, Kuhns, Douglas B., Ding, Li, Paulson, Michelle L., Marciano, Beatriz E., Gea-Banacloche, Juan C., Orange, Jordan S., Cuellar-Rodriguez, Jennifer, Hickstein, Dennis D., Holland, Steven M.

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Allogeneic Reduced-Intensity Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease: a Single-Center Prospective Trial von Parta, Mark, Kelly, Corin, Kwatemaa, Nana, Theobald, Narda, Hilligoss, Diane, Qin, Jing, Kuhns, Douglas B., Zerbe, Christa, Holland, Steven M., Malech, Harry, Kang, Elizabeth M.

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