4003 ORAL Age is Nothing but a Number – Management of Breast Cancer in the Elderly von Harries, R.L, Kugathasan, G, Jones, E.A, Faulkner, N, Gomez, K.F

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Management of breast cancer in the elderly: Age is nothing but a number von Harries, Rhiannon, Kugathasan, G, Jones, E, Faulkner, N, Gomez, K

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What shape do UK trainees want their training to be? Results of a cross-sectional study von Harries, RL, Rashid, M, Smitham, P, Vesey, A, McGregor, R, Scheeres, K, Bailey, J, Sohaib, SMA, Prior, M, Frost, J, Al-Deeb, W, Kugathasan, G, Gokani, VJ

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What shape do UK trainees want their training to be? Results of a cross-sectional study von Harries, RL, Rashid, M, Smitham, P, Vesey, A, McGregor, R, Scheeres, K, Bailey, J, Sohaib, SM, Prior, M, Frost, J, Al-Deeb, W, Kugathasan, G, Gokani, VJ

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A process modification for CMOS monolithic active pixel sensors for enhanced depletion, timing performance and radiation tolerance von Snoeys, W., Aglieri Rinella, G., Hillemanns, H., Kugathasan, T., Mager, M., Musa, L., Riedler, P., Reidt, F., Van Hoorne, J., Fenigstein, A., Leitner, T.

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Dynamics of metatranscription in the inflammatory bowel disease gut microbiome von Schirmer, Melanie, Franzosa, Eric A., Lloyd-Price, Jason, McIver, Lauren J., Schwager, Randall, Poon, Tiffany W., Ananthakrishnan, Ashwin N., Andrews, Elizabeth, Barron, Gildardo, Lake, Kathleen, Prasad, Mahadev, Sauk, Jenny, Stevens, Betsy, Wilson, Robin G., Braun, Jonathan, Denson, Lee A., Kugathasan, Subra, McGovern, Dermot P. B., Vlamakis, Hera, Xavier, Ramnik J., Huttenhower, Curtis

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Increased Immune Reactivity Predicts Aggressive Complicating Crohn's Disease in Children von Dubinsky, Marla C, Kugathasan, Subra, Mei, Ling, Picornell, Yoana, Nebel, Justin, Wrobel, Iwona, Quiros, Antonio, Silber, Gary, Wahbeh, Ghassan, Katzir, Lirona, Vasiliauskas, Eric, Bahar, Ron, Otley, Anthony, Mack, David, Evans, Jonathan, Rosh, Joel, Hemker, Maria Oliva, Leleiko, Neal, Crandall, Wallace, Langton, Christine, Landers, Carol, Taylor, Kent D, Targan, Stephan R, Rotter, Jerome I, Markowitz, James, Hyams, Jeffrey

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Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients von Sharma, Kumar, Zhang, Guanshi, Hansen, Jens, Bjornstad, Petter, Lee, Hak Joo, Menon, Rajasree, Hejazi, Leila, Liu, Jian-Jun, Franzone, Anthony, Looker, Helen C, Choi, Byeong Yeob, Fernandez, Roman, Venkatachalam, Manjeri A, Kugathasan, Luxcia, Sridhar, Vikas S, Natarajan, Loki, Zhang, Jing, Sharma, Varun S, Kwan, Brian, Waikar, Sushrut S, Himmelfarb, Jonathan, Tuttle, Katherine R, Kestenbaum, Bryan, Fuhrer, Tobias, Feldman, Harold I, de Boer, Ian H, Tucci, Fabio C, Sedor, John, Heerspink, Hiddo Lambers, Schaub, Jennifer, Otto, Edgar A, Hodgin, Jeffrey B, Kretzler, Matthias, Anderton, Christopher R, Alexandrov, Theodore, Cherney, David, Lim, Su Chi, Nelson, Robert G, Gelfond, Jonathan, Iyengar, Ravi

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NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease von Schwerd, T, Bryant, R V, Pandey, S, Capitani, M, Meran, L, Cazier, J-B, Jung, J, Mondal, K, Parkes, M, Mathew, C G, Fiedler, K, McCarthy, D J, Sullivan, P B, Rodrigues, A, Travis, S P L, Moore, C, Sambrook, J, Ouwehand, W H, Roberts, D J, Danesh, J, Russell, R K, Wilson, D C, Kelsen, J R, Cornall, R, Denson, L A, Kugathasan, S, Knaus, U G, Serra, E G, Anderson, C A, Duerr, R H, McGovern, D PB, Cho, J, Powrie, F, Li, V SW, Muise, A M, Uhlig, H H

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Magnetic Resonance Enterography Healing and Magnetic Resonance Enterography Remission Predicts Improved Outcome in Pediatric Crohn Disease von Sauer, Cary G., Middleton, Jeremy P., McCracken, Courtney, Loewen, Jonathan, Braithwaite, Kiery, Alazraki, Adina, Martin, Diego R., Kugathasan, Subra

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Production of light nuclei and anti-nuclei in pp and Pb-Pb collisions at energies available at the CERN Large Hadron Collider von Adam, Jaroslav, Adamová, Dagmar, Aggarwal, Madan M, Aglieri Rinella, Gianluca, Agnello, Michelangelo, Agrawal, Nikita, Ahammed, Zubayer, Ahmed, Ijaz, Ahn, Sang Un, Aiola, Salvatore, Alme, Johan, Helstrup, Håvard, Hetland, Kristin Fanebust, Kileng, Bjarte, Altinpinar, Sedat, Djuvsland, Øystein, Haaland, Øystein Senneset, Huang, Meidana, Lønne, Per-Ivar, Nystrand, Joakim, Rehman, Attiq ur, Røhrich, Dieter, Ullaland, Kjetil, Velure, Arild, Wagner, Boris, Zhang, Hui, Zhou, Zhuo, Zhu, Hongsheng, Arsene, Ionut Christian, Bätzing, Paul Christoph, Dordic, Olja, Lindal, Svein, Mahmood, Sohail Musa, Milosevic, Jovan, Qvigstad, Henrik, Richter, Matthias, Røed, Ketil, Skaali, Toralf Bernhard, Tveter, Trine Spedstad, Wikne, Jon Christopher, Zhao, Chengxin, Langøy, Rune, Lien, Jørgen André, Ajaz, Muhammad, Akindinov, Alexander, Alam, Sk Noor, Aleksandrov, Dimitry, Alessandro, Bruno, Alexandre, Didier, Alfaro Molina, José Rubén, ALICE, Collaboration

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Performance of the ALICE experiment at the CERN LHC von Agnello, M., Agrawal, N., Ahn, S. U., Andrei, C., Arcelli, S., Arnaldi, R., Averbeck, R., Basu, S., Bogolyubsky, M., Book, J., Broker, T. A., Browning, T. A., Busch, O., Catanescu, V., Cortes Maldonado, I., Crochet, P., Das, K., Dordic, O., Majumdar, A. K. Dutta, Fiore, E. M., Garabatos, C., Ghosh, P., Gianotti, P., Grelli, A., Grion, N., Grosso, R., Haaland, O., Hamagaki, H., Heide, M., Herghelegiu, A., Hess, B. A., Hladky, J., Jacobs, P. M., Kang, J. H., Ketzer, B., Khan, S. A., Khanzadeev, A., Kretz, M., Kucheriaev, Y., Kurashvili, P., Lea, R., Leoncino, M., Li, S., Lien, J., Mahapatra, D. P., Margagliotti, G. V., Martin, N. A., Blanco, J. Martin, Meddi, F., Perez, J. Mercado, Milosevic, J., Mitu, C. M., Murray, S., Nomokonov, P., Nooren, G., Nystrand, J., Okatan, A., Pagano, P., Pajares, C., Da Costa, H. Pereira, Pestov, Y., Pochybova, S., Poljak, N., Pop, A., Reed, R. J., Rehman, A., Reygers, K., Rossegger, S., Roy, A., Rubio Montero, A. J., Safarik, K., Sambyal, S., Santagati, G., Schmidt, C., Schukraft, J., Seo, J., Shtejer, K., Simatovic, G., Snellings, R. J. M., Sorensen, S., Sputowska, I., Srivastava, B. K., Stachel, J., Stefanek, G., Stenlund, Evert, Stolpovskiy, M., Sumbera, M., Szarka, I., Peloni, A. Tarantola, Tarzila, M. G., Usai, G. L., Vranic, D., Weber, S. G., Wilkinson, J., Winn, M., Yaldo, C. G., Zaporozhets, S., Zavada, P., Zgura, I. S., Zhou, F.

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Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response von Haberman, Yael, Karns, Rebekah, Dexheimer, Phillip J., Schirmer, Melanie, Somekh, Judith, Jurickova, Ingrid, Braun, Tzipi, Novak, Elizabeth, Bauman, Laura, Collins, Margaret H., Mo, Angela, Rosen, Michael J., Bonkowski, Erin, Gotman, Nathan, Marquis, Alison, Nistel, Mason, Rufo, Paul A., Baker, Susan S., Sauer, Cary G., Markowitz, James, Pfefferkorn, Marian D., Rosh, Joel R., Boyle, Brendan M., Mack, David R., Baldassano, Robert N., Shah, Sapana, Leleiko, Neal S., Heyman, Melvin B., Grifiths, Anne M., Patel, Ashish S., Noe, Joshua D., Aronow, Bruce J., Kugathasan, Subra, Walters, Thomas D., Gibson, Greg, Thomas, Sonia Davis, Mollen, Kevin, Shen-Orr, Shai, Huttenhower, Curtis, Xavier, Ramnik J., Hyams, Jeffrey S., Denson, Lee A.

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Management of Anti‐drug Antibodies to Biologic Medications in Children With Inflammatory Bowel Disease von Cohen, Reuven Zev, Schoen, Bess T., Kugathasan, Subra, Sauer, Cary G.

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Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease von Kugathasan, S, Saubermann, L J, Smith, L, Kou, D, Itoh, J, Binion, D G, Levine, A D, Blumberg, R S, Fiocchi, C

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Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease von Shaw, Kelly A, Bertha, Madeline, Hofmekler, Tatyana, Chopra, Pankaj, Vatanen, Tommi, Srivatsa, Abhiram, Prince, Jarod, Kumar, Archana, Sauer, Cary, Zwick, Michael E, Satten, Glen A, Kostic, Aleksandar D, Mulle, Jennifer G, Xavier, Ramnik J, Kugathasan, Subra

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Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease von Potdar, Alka A., Dube, Shishir, Naito, Takeo, Li, Katherine, Botwin, Gregory, Haritunians, Talin, Li, Dalin, Casero, David, Yang, Shaohong, Bilsborough, Janine, Perrigoue, Jacqueline G., Denson, Lee A., Daly, Mark, Targan, Stephan R., Fleshner, Phillip, Braun, Jonathan, Kugathasan, Subra, Stappenbeck, Thaddeus S., McGovern, Dermot P.B.

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Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function von Washburn, Savannah, Maddipatla, Sushma C, Murthy, Shanta, Dodd, Anne, Pelia, Ranjit S, Kolachala, Vasantha L, Geem, Duke, Matthews, Jason D, Gibson, Greg, Kugathasan, Subra

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Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study von Hyams, Jeffrey S, Davis Thomas, Sonia, Gotman, Nathan, Haberman, Yael, Karns, Rebekah, Schirmer, Melanie, Mo, Angela, Mack, David R, Boyle, Brendan, Griffiths, Anne M, LeLeiko, Neal S, Sauer, Cary G, Keljo, David J, Markowitz, James, Baker, Susan S, Rosh, Joel, Baldassano, Robert N, Patel, Ashish, Pfefferkorn, Marian, Otley, Anthony, Heyman, Melvin, Noe, Joshua, Oliva-Hemker, Maria, Rufo, Paul A, Strople, Jennifer, Ziring, David, Guthery, Stephen L, Sudel, Boris, Benkov, Keith, Wali, Prateek, Moulton, Dedrick, Evans, Jonathan, Kappelman, Michael D, Marquis, M Alison, Sylvester, Francisco A, Collins, Margaret H, Venkateswaran, Suresh, Dubinsky, Marla, Tangpricha, Vin, Spada, Krista L, Saul, Bradley, Wang, Jessie, Serrano, Jose, Hommel, Kevin, Marigorta, Urko M, Gibson, Greg, Xavier, Ramnik J, Kugathasan, Subra, Walters, Thomas, Denson, Lee A

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Design and readout architecture of a monolithic binary active pixel sensor in TPSCo 65 nm CMOS imaging technology von Cecconi, L., Piro, F., de Melo, J.L.A., Deng, W., Hong, G.H., Snoeys, W., Mager, M., Suljic, M., Kugathasan, T., Buckland, M., Aglieri Rinella, G., Leitao, P.V., Reidt, F., Baudot, J., Bugiel, S., Colledani, C., Contin, G., Hu, C., Kluge, A., Kluit, R., Vitkovskiy, A., Russo, R., Becht, P., Grelli, A., Hasenbichler, J., Munker, M., Soltveit, H.K., Menzel, M.W., Sonneveld, J., Tiltmann, N.

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