Effects of Solution Conditions, Processing Parameters, and Container Materials on Aggregation of a Monoclonal Antibody during Freeze-Thawing von Kueltzo, Lisa A., Wang, W.e.i., Randolph, Theodore W., Carpenter, John F.

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Structure-Based Design of Nipah Virus Vaccines: A Generalizable Approach to Paramyxovirus Immunogen Development von Loomis, Rebecca J., Stewart-Jones, Guillaume B. E., Tsybovsky, Yaroslav, Caringal, Ria T., Morabito, Kaitlyn M., McLellan, Jason S., Chamberlain, Amy L., Nugent, Sean T., Hutchinson, Geoffrey B., Kueltzo, Lisa A., Mascola, John R., Graham, Barney S.

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Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine von Loomis, Rebecca J., DiPiazza, Anthony T., Falcone, Samantha, Ruckwardt, Tracy J., Morabito, Kaitlyn M., Abiona, Olubukola M., Chang, Lauren A., Caringal, Ria T., Presnyak, Vladimir, Narayanan, Elisabeth, Tsybovsky, Yaroslav, Nair, Deepika, Hutchinson, Geoffrey B., Stewart-Jones, Guillaume B. E., Kueltzo, Lisa A., Himansu, Sunny, Mascola, John R., Carfi, Andrea, Graham, Barney S.

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Removal of variable domain N-linked glycosylation as a means to improve the homogeneity of HIV-1 broadly neutralizing antibodies von Chuang, Gwo-Yu, Asokan, Mangaiarkarasi, Ivleva, Vera B., Pegu, Amarendra, Yang, Eun Sung, Zhang, Baoshan, Chaudhuri, Rajoshi, Geng, Hui, Lin, Bob C., Louder, Mark K., McKee, Krisha, O'Dell, Sijy, Wang, Hairong, Zhou, Tongqing, Doria-Rose, Nicole A., Kueltzo, Lisa A., Lei, Q. Paula, Mascola, John R., Kwong, Peter D.

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Low-dose intravenous and subcutaneous CIS43LS monoclonal antibody for protection against malaria (VRC 612 Part C): a phase 1, adaptive trial von Lyke, Kirsten E, Berry, Andrea A, Mason, Kaitlin, Idris, Azza H, O'Callahan, Mark, Happe, Myra, Strom, Larisa, Berkowitz, Nina M, Guech, Mercy, Hu, Zonghui, Castro, Mike, Basappa, Manjula, Wang, Lu, Low, Kwang, Holman, LaSonji A, Mendoza, Floreliz, Gordon, Ingelise J, Plummer, Sarah H, Trofymenko, Olga, Strauss, Kathleen S, Joshi, Sudhaunshu, Shrestha, Biraj, Adams, Matthew, Chagas, Andrezza Campos, Murphy, Jittawadee R, Stein, Judy, Hickman, Somia, McDougal, Andrew, Lin, Bob, Narpala, Sandeep R, Vazquez, Sandra, Serebryannyy, Leonid, McDermott, Adrian, Gaudinski, Martin R, Capparelli, Edmund V, Coates, Emily E, Wu, Richard L, Ledgerwood, Julie E, Dropulic, Lesia K, Seder, Robert A, Young, Cheryl, Boyce, Colleen, Winkler, Jennifer, Holian, Susan, Greenberg, Nancy, George, Shirley, Kwon, Alyson, Dorsey, Brenda, Da Costa, Ana Raquel, Witt, William, Grays, Daryl, Gapasin, Arren, Bernal, Paula, Floyd, Jeffrey, Goldstein, Eric, Howe, Leslie, Lee, Myounghee, Marron, Jennifer, Brooks, Kelly, Turek, Lisa, Farley, Patricia, Frels, Shantel, Booth, Delores, Gall, Jason, Carlton, Kevin, Albright, Gabriela, Amharref, Nadia, Atallah, Kandace, Banappagari, Sashikanth, Bastani, Niutish, Blackstock, Daniel, Boonyaratanakornkit, Bobby, Carey, Elizabeth, Charlton, Adam, Chaudhuri, Rajoshi, Caringal, Alegria M., Chen, Mingzhong, Chen, Peifeng, Cheng, Wei, Gowetski, Daniel, Gulla, Krishana, Hastings, Erica, Horwitz, Joe, Ivleva, Vera, Kordella, Dan, Kueltzo, Lisa A., Lagler, Sara, Le, Matt, Lee, James, Lei, Paula, Li, Yile, Nagy, Attila, Patel, Aakash, Runsewe, Peyi, Shadrick, Will, Shetty, Shamitha, Wang, Hairong, Webber, Calvin, Vejzagic, Farah, Yang, Yoo-Jung

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Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial von Ruckwardt, Tracy J, Morabito, Kaitlyn M, Phung, Emily, Crank, Michelle C, Costner, Pamela J, Holman, LaSonji A, Chang, Lauren A, Hickman, Somia P, Berkowitz, Nina M, Gordon, Ingelise J, Yamshchikov, Galina V, Gaudinski, Martin R, Lin, Bob, Bailer, Robert, Chen, Man, Ortega-Villa, Ana M, Nguyen, Thuy, Kumar, Azad, Schwartz, Richard M, Kueltzo, Lisa A, Stein, Judith A, Carlton, Kevin, Gall, Jason G, Nason, Martha C, Mascola, John R, Chen, Grace, Graham, Barney S, Arthur, Anita, Cunningham, Jennifer, Eshun, Aba, Larkin, Brenda, Mendoza, Floreliz, Novik, Laura, Saunders, Jamie, Wang, Xiaolin, Whalen, William, Carter, Cristina, Hendel, Cynthia Starr, Plummer, Sarah, Ola, Abidemi, Widge, Alicia, Burgos Florez, Maria C, Le, Lam, Pittman, Iris, Rothwell, Ro Shauna S, Trofymenko, Olga, Vasilenko, Olga, Apte, Preeti, Hicks, Renunda, Cartagena, Cora Trelles, Williams, Pernell, Requilman, LaShawn, Tran, Colin, Bai, Shufeng, Carey, Elizabeth, Chamberlain, Amy L, Chang, Ya-chen, Chen, Mingzhong, Chen, Peifeng, Cooper, Jon, Fridley, Colleen, Ghosh, Mridul, Gollapudi, Deepika, Holland-Linn, Janel, Horwitz, Joe, Hussain, Althaf, Ivleva, Vera, Kaltovich, Florence, Leach, Kristin, Lee, Christopher, Liu, Amy, Liu, Xun, Manceva, Slobodanka, Menon, Amritha, Nagy, Attila, O'Connell, Sarah, Ragunathan, Rahul, Walters, Jennifer, Zhao, Zhong

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A Micro–Polyethylene Glycol Precipitation Assay as a Relative Solubility Screening Tool for Monoclonal Antibody Design and Formulation Development von Toprani, Vishal M., Joshi, Sangeeta B., Kueltzo, Lisa A., Schwartz, Richard M., Middaugh, C. Russell, Volkin, David B.

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Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant von Francica, Joseph R, Lynn, Geoffrey M, Laga, Richard, Joyce, M. Gordon, Ruckwardt, Tracy J, Morabito, Kaitlyn M, Chen, Man, Chaudhuri, Rajoshi, Zhang, Baoshan, Sastry, Mallika, Ko, Kiyoon, Choe, Misook, Pechar, Michal, Georgiev, Ivelin S, Kueltzo, Lisa A, Seymour, Leonard W, Mascola, John R, Kwong, Peter D, Graham, Barney S, Seder, Robert A

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Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody von Kwon, Young D., Chuang, Gwo-Yu, Zhang, Baoshan, Bailer, Robert T., Doria-Rose, Nicole A., Gindin, Tatyana S., Lin, Bob, Louder, Mark K., McKee, Krisha, O’Dell, Sijy, Pegu, Amarendra, Schmidt, Stephen D., Asokan, Mangaiarkarasi, Chen, Xuejun, Choe, Misook, Georgiev, Ivelin S., Jin, Vivian, Pancera, Marie, Rawi, Reda, Wang, Keyun, Chaudhuri, Rajoshi, Kueltzo, Lisa A., Manceva, Slobodanka D., Todd, John-Paul, Scorpio, Diana G., Kim, Mikyung, Reinherz, Ellis L., Wagh, Kshitij, Korber, Bette M., Connors, Mark, Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.

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Structure-Function Analysis of Invasion Plasmid Antigen C (IpaC) from Shigella flexneri von Kueltzo, Lisa A, Osiecki, John, Barker, Jeff, Picking, Wendy L, Ersoy, Baran, Picking, William D, Middaugh, C Russell

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Structural Characterization and Formulation Development of a Trivalent Equine Encephalitis Virus-Like Particle Vaccine Candidate von Toprani, Vishal M., Cheng, Yuan, Wahome, Newton, Khasa, Harshit, Kueltzo, Lisa A., Schwartz, Richard M., Middaugh, C. Russell, Joshi, Sangeeta B., Volkin, David B.

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Development of a Stable Virus-Like Particle Vaccine Formulation against Chikungunya Virus and Investigation of the Effects of Polyanions von Kramer, Ryan M., Zeng, Yuhong, Sahni, Neha, Kueltzo, Lisa A., Schwartz, Richard M., Srivastava, Indresh K., Crane, Lindsey, Joshi, Sangeeta B., Volkin, David B., Russell Middaugh, C.

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A Monoclonal Antibody for Malaria Prevention von Gaudinski, Martin R, Berkowitz, Nina M, Idris, Azza H, Coates, Emily E, Holman, LaSonji A, Mendoza, Floreliz, Gordon, Ingelise J, Plummer, Sarah H, Trofymenko, Olga, Hu, Zonghui, Campos Chagas, Andrezza, O’Connell, Sarah, Basappa, Manjula, Douek, Naomi, Narpala, Sandeep R, Barry, Christopher R, Widge, Alicia T, Hicks, Renunda, Awan, Seemal F, Wu, Richard L, Hickman, Somia, Wycuff, Diane, Stein, Judy A, Case, Christopher, Evans, Brian P, Carlton, Kevin, Gall, Jason G, Vazquez, Sandra, Flach, Britta, Chen, Grace L, Francica, Joseph R, Flynn, Barbara J, Kisalu, Neville K, Capparelli, Edmund V, McDermott, Adrian, Mascola, John R, Ledgerwood, Julie E, Seder, Robert A

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Derivative Absorbance Spectroscopy and Protein Phase Diagrams as Tools for Comprehensive Protein Characterization: A bGCSF Case Study von Kueltzo, Lisa A., Ersoy, Baran, Ralston, John P., Middaugh, C.Russell

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Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria von Wu, Richard L., Idris, Azza H., Berkowitz, Nina M., Happe, Myra, Gaudinski, Martin R., Buettner, Christian, Strom, Larisa, Awan, Seemal F., Holman, LaSonji A., Mendoza, Floreliz, Gordon, Ingelise J., Hu, Zonghui, Campos Chagas, Andrezza, Wang, Lawrence T., Da Silva Pereira, Lais, Francica, Joseph R., Kisalu, Neville K., Flynn, Barbara J., Shi, Wei, Kong, Wing-Pui, O’Connell, Sarah, Plummer, Sarah H., Beck, Allison, McDermott, Adrian, Narpala, Sandeep R., Serebryannyy, Leonid, Castro, Mike, Silva, Rosa, Imam, Marjaan, Pittman, Iris, Hickman, Somia P., McDougal, Andrew J., Lukoskie, Ashly E., Murphy, Jittawadee R., Gall, Jason G., Carlton, Kevin, Morgan, Patricia, Seo, Ellie, Stein, Judy A., Vazquez, Sandra, Telscher, Shinyi, Capparelli, Edmund V., Coates, Emily E., Mascola, John R., Ledgerwood, Julie E., Dropulic, Lesia K., Seder, Robert A.

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Safety and immunogenicity of a trivalent virus-like particle vaccine against western, eastern, and Venezuelan equine encephalitis viruses: a phase 1, open-label, dose-escalation, r... von Coates, Emily E, Edupuganti, Srilatha, Chen, Grace L, Happe, Myra, Strom, Larisa, Widge, Alicia, Florez, Maria Burgos, Cox, Josephine H, Gordon, Ingelise, Plummer, Sarah, Ola, Abidemi, Yamshchikov, Galina, Andrews, Charla, Curate-Ingram, Sharon, Morgan, Patricia, Nagar, Shashi, Collins, Matthew H, Bray, Amy, Nguyen, Thuy, Stein, Judy, Case, Christopher L, Kaltovich, Florence, Wycuff, Diane, Liang, C Jason, Carlton, Kevin, Vazquez, Sandra, Mascola, John R, Ledgerwood, Julie E

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Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen von Ou, Li, Kong, Wing-Pui, Chuang, Gwo-Yu, Ghosh, Mridul, Gulla, Krishana, O’Dell, Sijy, Varriale, Joseph, Barefoot, Nathan, Changela, Anita, Chao, Cara W., Cheng, Cheng, Druz, Aliaksandr, Kong, Rui, McKee, Krisha, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Shaddeau, Andrew, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Shuishu, Wanninger, Timothy G., Xu, Kai, Yang, Gengcheng J., Zhang, Baoshan, Zhang, Yaqiu, Zhou, Tongqing, Arnold, Frank J., Doria-Rose, Nicole A., Lei, Q. Paula, Ryan, Edward T., Vann, Willie F., Mascola, John R., Kwong, Peter D.

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Nonclassical Transport Proteins and Peptides: An Alternative to Classical Macromolecule Delivery Systems von Kueltzo, Lisa A., Middaugh, C.Russell

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Structural Characterization of Bovine Granulocyte Colony Stimulating Factor: Effect of Temperature and pH von Kueltzo, Lisa A., Middaugh, C.Russell

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Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine von Casazza, Joseph P., Hofstetter, Amelia R., Costner, Pamela J. M., Holman, LaSonji A., Hendel, Cynthia S., Widge, Alicia T., Wu, Richard L., Whalen, William R., Cunningham, Jennifer, Arthur, Anita, Wang, Xiaolin, Ola, Abidemi, Saunders, Jamie, Mendoza, Floreliz, Novik, Laura, Burgos Florez, Maria C., Ortega-Villa, Ana M., Apte, Preeti J., Strom, Larisa, Wang, Lu, Imam, Marjaan, Basappa, Manjula, Naisan, Mursal, Castro, Mike, Trost, Jessica F., Narpala, Sandeep R., Vanderven, Hillary A., Yamshchikov, Galina V., Berkowitz, Nina M., Gordon, Ingelise J., Plummer, Sarah H., Wycuff, Diane L., Vazquez, Sandra, Gillespie, Rebecca A., Creanga, Adrian, Adams, William C., Carlton, Kevin, Gall, Jason G., McDermott, Adrian B., Serebryannyy, Leonid A., Houser, Katherine V., Koup, Richard A., Graham, Barney S., Ledgerwood, Julie E., Mascola, John R., Pierson, Theodore C., Andrews, Sarah F., Kanekiyo, Masaru, Dropulic, Lesia K.

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