An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction von Zhu, Chen, Sakuishi, Kaori, Xiao, Sheng, Sun, Zhiyi, Zaghouani, Sarah, Gu, Guangxiang, Wang, Chao, Tan, Dewar J., Wu, Chuan, Rangachari, Manu, Pertel, Thomas, Jin, Hyun-Tak, Ahmed, Rafi, Anderson, Ana C., Kuchroo, Vijay K.

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Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content von Brauner, Susanna, Jiang, Xintong, Thorlacius, Gudny Ella, Lundberg, Anna M, Östberg, Therese, Yan, Zhong-Qun, Kuchroo, Vijay K, Hansson, Göran K, Wahren-Herlenius, Marie

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The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity von Kuchroo, Vijay K, Zhu, Chen, Anderson, Ana C, Schubart, Anna, Xiong, Huabao, Imitola, Jaime, Khoury, Samia J, Zheng, Xin Xiao, Strom, Terry B

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Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway von Espinosa, Alexander, Dardalhon, Valerie, Brauner, Susanna, Ambrosi, Aurelie, Higgs, Rowan, Quintana, Fransisco J, Sjöstrand, Maria, Eloranta, Maija-Leena, Ní Gabhann, Joan, Winqvist, Ola, Sundelin, Birgitta, Jefferies, Caroline A, Rozell, Björn, Kuchroo, Vijay K, Wahren-Herlenius, Marie

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H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production von Brauner, S, Folkersen, L, Kvarnstrom, M, Meisgen, S, Petersen, S, Franzen-Malmros, M, Mofors, J, Brokstad, KA, Klareskog, L, Jonsson, R, Westerberg, LS, Trollmo, C, Malmstrom, V, Ambrosi, A, Kuchroo, VK, Nordmark, G, Wahren-Herlenius, M

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Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis von Bettelli, Estelle, Sullivan, Brandon, Szabo, Susanne J, Sobel, Raymond A, Glimcher, Laurie H, Kuchroo, Vijay K

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IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together von Bettelli, Estelle, Kuchroo, Vijay K

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PD-L1-Deficient Mice Show That PD-L1 on T Cells, Antigen-Presenting Cells, and Host Tissues Negatively Regulates T Cells von Latchman, Yvette E., Liang, Spencer C., Wu, Yin, Chernova, Tatyana, Sobel, Raymond A., Klemm, Martina, Kuchroo, Vijay K., Freeman, Gordon J., Sharpe, Arlene H., Nathenson, Stanley G.

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IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy von Krueger, James G, Eyerich, Kilian, Kuchroo, Vijay K, Ritchlin, Christopher T, Abreu, Maria T, Elloso, M Merle, Fourie, Anne, Fakharzadeh, Steven, Sherlock, Jonathan P, Yang, Ya-Wen, Cua, Daniel J, McInnes, Iain B

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Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function von Meisgen, S, Hedlund, M, Ambrosi, A, Folkersen, L, Ottosson, V, Forsberg, D, Thorlacius, GE, Biavati, L, Strandberg, L, Mofors, J, Ramskold, D, Ruhrmann, S, Meneghel, L, Nyberg, W, Espinosa, A, Hamilton, RM, Franco-Cereceda, A, Hamsten, A, Olsson, T, Greene, L, Eriksson, P, Gemzell-Danielsson, K, Salomonsson, S, Kuchroo, VK, Herlenius, E, Kockum, I, Sonesson, SE, Wahren-Herlenius, M

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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease von Kuchroo, Vijay K, Monney, Laurent, Sabatos, Catherine A, Gaglia, Jason L, Ryu, Akemi, Waldner, Hanspeter, Chernova, Tatyana, Manning, Stephen, Greenfield, Edward A, Coyle, Anthony J, Sobel, Raymond A, Freeman, Gordon J

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Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors von Sjöstrand, Maria, Ambrosi, Aurélie, Brauner, Susanna, Sullivan, Jenna, Malin, Stephen, Kuchroo, Vijay K, Espinosa, Alexander, Wahren-Herlenius, Marie

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Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance von Kuchroo, Vijay K, Sabatos, Catherine A, Chakravarti, Sumone, Cha, Eugene, Schubart, Anna, Sánchez-Fueyo, Alberto, Zheng, Xin Xiao, Coyle, Anthony J, Strom, Terry B, Freeman, Gordon J

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Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance von Domenig, Christoph, Coyle, Anthony J, Gutiérrez-Ramos, José-Carlos, Manlongat, Natasha, Kuchroo, Vijay K, Sánchez-Fueyo, Alberto, Sabatos, Catherine A, Picarella, Dominic, Zheng, Xin Xiao, Bender, Orissa, Strom, Terry B, Tian, Jane, Kamradt, Thomas

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Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease von Waldner, Hanspeter, Collins, Mary, Kuchroo, Vijay K.

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The TIM gene family regulates autoimmune and allergic diseases von Meyers, Jennifer Hartt, Sabatos, Catherine A., Chakravarti, Sumone, Kuchroo, Vijay K.

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T CELL RESPONSE IN EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE): Role of Self and Cross-Reactive Antigens in Shaping, Tuning, and Regulating the Autopathogenic T Cell Repertoire von Kuchroo, Vijay K, Anderson, Ana C, Waldner, Hanspeter, Munder, Markus, Bettelli, Estelle, Nicholson, Lindsay B

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TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation von Kuchroo, Vijay K, Meyers, Jennifer Hartt, Chakravarti, Sumone, Schlesinger, David, Illes, Zsolt, Waldner, Hanspeter, Umetsu, Sarah E, Kenny, James, Zheng, Xin Xiao, Umetsu, Dale T, DeKruyff, Rosemarie H, Strom, Terry B

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The Sjogren's Syndrome-Associated Autoantigen Ro52 Is an E3 Ligase That Regulates Proliferation and Cell Death von Espinosa, Alexander, Zhou, Wei, Ek, Monica, Hedlund, Malin, Brauner, Susanna, Popovic, Karin, Horvath, Linn, Wallerskog, Therese, Oukka, Mohamed, Nyberg, Filippa, Kuchroo, Vijay K, Wahren-Herlenius, Marie

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Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family von DeKruyff, Rosemarie H, McIntire, Jennifer J, Umetsu, Sarah E, Akbari, Omid, Potter, Michael, Kuchroo, Vijay K, Barsh, Gregory S, Freeman, Gordon J, Umetsu, Dale T

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