Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes von Kucherlapati, Melanie

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Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice von Kovalenko, Marina, Dragileva, Ella, St Claire, Jason, Gillis, Tammy, Guide, Jolene R, New, Jaclyn, Dong, Hualing, Kucherlapati, Raju, Kucherlapati, Melanie H, Ehrlich, Michelle E, Lee, Jong-Min, Wheeler, Vanessa C

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An Msh2 Conditional Knockout Mouse for Studying Intestinal Cancer and Testing Anticancer Agents von Kucherlapati, Melanie H, Lee, Kyeryoung, Nguyen, Andrew A, Clark, Alan B, Hou, Harry, Rosulek, Andrew, Li, Hua, Yang, Kan, Fan, Kunhua, Lipkin, Martin, Bronson, Roderick T, Jelicks, Linda, Kunkel, Thomas A, Kucherlapati, Raju, Edelmann, Winfried

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Mouse models in colon cancer, inferences, and implications von Kucherlapati, Melanie Haas

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Global impact of somatic structural variation on the DNA methylome of human cancers von Zhang, Yiqun, Yang, Lixing, Kucherlapati, Melanie, Hadjipanayis, Angela, Pantazi, Angeliki, Bristow, Christopher A, Lee, Eunjung Alice, Mahadeshwar, Harshad S, Tang, Jiabin, Zhang, Jianhua, Seth, Sahil, Lee, Semin, Ren, Xiaojia, Song, Xingzhi, Sun, Huandong, Seidman, Jonathan, Luquette, Lovelace J, Xi, Ruibin, Chin, Lynda, Protopopov, Alexei, Park, Peter J, Kucherlapati, Raju, Creighton, Chad J

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A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases von Zhang, Yiqun, Yang, Lixing, Kucherlapati, Melanie, Chen, Fengju, Hadjipanayis, Angela, Pantazi, Angeliki, Bristow, Christopher A., Lee, Eunjung A., Mahadeshwar, Harshad S., Tang, Jiabin, Zhang, Jianhua, Seth, Sahil, Lee, Semin, Ren, Xiaojia, Song, Xingzhi, Sun, Huandong, Seidman, Jonathan, Luquette, Lovelace J., Xi, Ruibin, Chin, Lynda, Protopopov, Alexei, Li, Wei, Park, Peter J., Kucherlapati, Raju, Creighton, Chad J.

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Genotype directed therapy in murine mismatch repair deficient tumors von Kucherlapati, Melanie H, Esfahani, Shadi, Habibollahi, Peiman, Wang, Junning, Still, Eric R, Bronson, Roderick T, Mahmood, Umar, Kucherlapati, Raju S

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A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease von McDonald, David A, Shenkar, Robert, Shi, Changbin, Stockton, Rebecca A, Akers, Amy L, Kucherlapati, Melanie H, Kucherlapati, Raju, Brainer, James, Ginsberg, Mark H, Awad, Issam A, Marchuk, Douglas A

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A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains von Mignot, Emmanuel, Peyron, Christelle, Faraco, Juliette, Rogers, William, Ripley, Beth, Overeem, Sebastiaan, Charnay, Yves, Nevsimalova, Sona, Aldrich, Michael, Reynolds, David, Albin, Roger, Li, Robin, Hungs, Marcel, Pedrazzoli, Mario, Padigaru, Muralidhara, Kucherlapati, Melanie, Fan, Jun, Maki, Richard, Lammers, Gert Jan, Bouras, Constantin, Kucherlapati, Raju, Nishino, Seiji

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Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice von Kortüm, Benedikt, Campregher, Christoph, Lang, Michaela, Khare, Vineeta, Pinter, Matthias, Evstatiev, Rayko, Schmid, Gerald, Mittlböck, Martina, Scharl, Theresa, Kucherlapati, Melanie H, Edelmann, Winfried, Gasche, Christoph

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An EGFR targeted PET imaging probe for the detection of colonic adenocarcinomas in the setting of colitis von Turker, N Selcan, Heidari, Pedram, Kucherlapati, Raju, Kucherlapati, Melanie, Mahmood, Umar

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Adenomatous polyposis coli (APC) is required for normal development of skin and thymus von Kuraguchi, Mari, Wang, Xiu-Ping, Bronson, Roderick T, Rothenberg, Rebecca, Ohene-Baah, Nana Yaw, Lund, Jennifer J, Kucherlapati, Melanie, Maas, Richard L, Kucherlapati, Raju

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Co-expression patterns explain how a basic transcriptional role for MYC modulates Wnt and MAPK pathways in colon and lung adenocarcinomas von Kucherlapati, Melanie Haas

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Optical imaging with a novel cathepsin-activatable probe for enhanced detection of colorectal cancer von Esfahani, Shadi A, Heidari, Pedram, Kucherlapati, Melanie H, Ferrer, Jorge M, Kucherlapati, Raju S, Mahmood, Umar

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MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas von Taguchi, Ayumu, Rho, Jung-Hyun, Yan, Qingxiang, Zhang, Yuzheng, Zhao, Yang, Xu, Hanwen, Tripathi, Satyendra Chandra, Wang, Hong, Brenner, Dean E, Kucherlapati, Melanie, Kucherlapati, Raju, Boutin, Adam T, Wang, Y Alan, DePinho, Ronald A, Feng, Ziding, Lampe, Paul D, Hanash, Samir M

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Haploinsufficiency of Flap Endonuclease (Fen1) Leads to Rapid Tumor Progression von Kucherlapati, Melanie, Yang, Kan, Kuraguchi, Mari, Zhao, Jie, Lia, Maria, Heyer, Joerg, Kane, Michael F., Fan, Kunhua, Russell, Robert, Anthony M. C. Brown, Kneitz, Burkhard, Edelmann, Winfried, Kolodner, Richard D., Lipkin, Martin, Kucherlapati, Raju

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A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease von MCDONALD, David A, SHENKAR, Robert, MARCHUK, Douglas A, SHI, Changbin, STOCKTON, Rebecca A, AKERS, Amy L, KUCHERLAPATI, Melanie H, KUCHERLAPATI, Raju, BRAINER, James, GINSBERG, Mark H, AWAD, Issam A

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Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model von McIlhatton, Michael A, Tyler, Jessica, Kerepesi, Laura A, Bocker-Edmonston, Tina, Kucherlapati, Melanie H, Edelmann, Winfried, Kucherlapati, Raju, Kopelovich, Levy, Fishel, Richard

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Modulation of proliferation factors in lung adenocarcinoma with an analysis of the transcriptional consequences of genomic EGFR activation von Kucherlapati, Melanie Haas

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80 Mesalazine Decreases Microsatellite Instability and Tumor Development in the Villin-Cre Msh2loxp/Loxp Mouse Model of Lynch Syndrome von Campregher, Christoph, Kortüm, Benedikt, Pinter, Matthias, Lang, Michaela, Evstatiev, Rayko, Khare, Vineeta, Kucherlapati, Melanie H, Edelmann, Winfried, Gasche, Christoph

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