A Compendium of Mutational Signatures of Environmental Agents von Kucab, Jill E., Zou, Xueqing, Morganella, Sandro, Joel, Madeleine, Nanda, A. Scott, Nagy, Eszter, Gomez, Celine, Degasperi, Andrea, Harris, Rebecca, Jackson, Stephen P., Arlt, Volker M., Phillips, David H., Nik-Zainal, Serena

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The genome as a record of environmental exposure von Nik-Zainal, Serena, Kucab, Jill E, Morganella, Sandro, Glodzik, Dominik, Alexandrov, Ludmil B, Arlt, Volker M, Weninger, Annette, Hollstein, Monica, Stratton, Michael R, Phillips, David H

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Metabolic Activation of Benzo[ a ]pyrene by Human Tissue Organoid Cultures von Caipa Garcia, Angela L, Kucab, Jill E, Al-Serori, Halh, Beck, Rebekah S S, Fischer, Franziska, Hufnagel, Matthias, Hartwig, Andrea, Floeder, Andrew, Balbo, Silvia, Francies, Hayley, Garnett, Mathew, Huch, Meritxell, Drost, Jarno, Zilbauer, Matthias, Arlt, Volker M, Phillips, David H

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Nutlin‐3a selects for cells harbouring TP53 mutations von Kucab, Jill E., Hollstein, Monica, Arlt, Volker M., Phillips, David H.

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Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism von Wohak, Laura E., Krais, Annette M., Kucab, Jill E., Stertmann, Julia, Øvrebø, Steinar, Seidel, Albrecht, Phillips, David H., Arlt, Volker M.

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Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation von Caipa Garcia, Angela L., Kucab, Jill E., Al-Serori, Halh, Beck, Rebekah S. S., Bellamri, Madjda, Turesky, Robert J., Groopman, John D., Francies, Hayley E., Garnett, Mathew J., Huch, Meritxell, Drost, Jarno, Zilbauer, Matthias, Arlt, Volker M., Phillips, David H.

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Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model von Kucab, Jill E, Phillips, David H, Arlt, Volker M

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Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells von SUTHERLAND, Brent W, KUCAB, Jill, LEIGHTON GRIMES, H, MILLER, Kathy, BADVE, Sunil, HUNTSMAN, David, BLAKE-GILKS, C, MIN CHEN, PALLEN, Catherine J, DUNN, Sandra E, WU, Joyce, LEE, Cathy, CHEANG, Maggie C. U, YORIDA, Erika, TURBIN, Dmitry, DEDHAR, Shoukat, NELSON, Colleen, POLLAK, Michael

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Mutagenicity of N‐hydroxy‐4‐aminobiphenyl in human TP53 knock‐in (Hupki) mouse embryo fibroblasts von Hölzl‐Armstrong, Lisa, Kucab, Jill E., Zwart, Edwin P., Luijten, Mirjam, Phillips, David H., Arlt, Volker M.

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Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania von Schmeiser, Heinz H., Kucab, Jill E., Arlt, Volker M., Phillips, David H., Hollstein, Monica, Gluhovschi, Gheorghe, Gluhovschi, Cristina, Modilca, Mirela, Daminescu, Liviu, Petrica, Ligia, Velciov, Silvia

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TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts von Kucab, Jill E., Zwart, Edwin P., van Steeg, Harry, Luijten, Mirjam, Schmeiser, Heinz H., Phillips, David H., Arlt, Volker M.

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Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours von Kucab, Jill E, Lee, Cathy, Chen, Ching-Shih, Zhu, Jiuxiang, Gilks, C Blake, Cheang, Maggie, Huntsman, David, Yorida, Erika, Emerman, Joanne, Pollak, Michael, Dunn, Sandra E

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Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts von Hölzl-Armstrong, Lisa, Kucab, Jill E, Korenjak, Michael, Luijten, Mirjam, Phillips, David H, Zavadil, Jiri, Arlt, Volker M

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Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts von Kucab, Jill E., Phillips, David H., Arlt, Volker M.

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Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology von Lynch, Anthony M, Zanoni, Thalita B, Salk, Jesse J, Martincorena, Inigo, Young, Robert R, Kucab, Jill, Valentine, Charles C, Yauk, Carole, Escobar, Patricia A, Witt, Kristine L, Frötschl, Roland, Reed, Simon H, Ashford, Anne

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Nutlin‐3a selects for cells harbouring TP 53 mutations von Kucab, Jill E., Hollstein, Monica, Arlt, Volker M., Phillips, David H.

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Celecoxib inhibits urokinase-type plasminogen activator (uPA) production in MDA-MB-231 breast cancer cells von ANDREWS, Heather N, HABIBI, Golerah, KUCAB, Jill E, DUNN, Sandra E

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The genome as a record for environmental exposure to polycyclic aromatic hydrocarbons von Arlt, Volker M., Kucab, Jill E., Joel, Madeleine, Nik-Zainal, Serena, Stratton, Michael R., Phillips, David H.

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Environmental polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53 dependent mechanism von Wohak, Laura U.E., Krais, Annette M., Kucab, Jill E., Ovrebo, Steinar, Seidel, Albrecht, Phillips, David H., Arlt, Volker M.

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Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model: Cancer aetiology and TP53 mutations von Kucab, Jill E., Phillips, David H., Arlt, Volker M.

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