Preponderance of Thiopurine S-Methyltransferase Deficiency and Heterozygosity Among Patients Intolerant to Mercaptopurine or Azathioprine von EVANS, William E, YUEN YI HON, MURRAY, Jeffrey, QUINN, John, RAVINDRANATH, Y, RITCHEY, Kim, ROBERTS, William, ROGERS, Zora R, SCHIFF, Deborah, STEUBER, Charles, TUCCI, Fabio, KORNEGAY, Nancy, BOMGAARS, Lisa, KRYNETSKI, Eugene Y, RELLING, Mary V, COUTRE, Steve, HOLDSWORTH, Mark, JANCO, Robert, KALWINSKY, David, KELLER, Frank, KHATIB, Ziad, MARGOLIN, Judy

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Structure and Dynamics of Thioguanine-modified Duplex DNA von Somerville, Lilla, Krynetski, Eugene Y, Krynetskaia, Natalia F, Beger, Richard D, Zhang, Weixing, Marhefka, Craig A, Evans, William E, Kriwacki, Richard W

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A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic Stress von Brown, Victor M., Krynetski, Eugene Y., Krynetskaia, Natalia F., Grieger, Dara, Mukatira, Suraj T., Murti, Kuruganti G., Slaughter, Clive A., Park, Hee-Won, Evans, William E.

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A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the c... von KRYNETSKI, Eugene Y, KRYNETSKAIA, Natalia F, BIANCHI, Marco E, EVANS, William E

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Polymorphism of the Thiopurine S-Methyltransferase Gene in African-Americans von Hon, Yuen Yi, Fessing, Michael Y., Pui, Ching-Hon, Relling, Mary V., Krynetski, Eugene Y., Evans, William E.

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Pharmacogenetics as a molecular basis for individualized drug therapy : The thiopurine S-methyltransferase paradigm von KRYNETSKI, E. Y, EVANS, W. E

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Enhanced Proteolysis of Thiopurine S-methyltransferase (TPMT) Encoded by Mutant Alleles in Humans (TPMT3A, TPMT2): Mechanisms for the Genetic Polymorphism of TPMT Activity von Tai, Hung-Liang, Krynetski, Eugene Y., Schuetz, Erin G., Yanishevski, Yuri, Evans, William E.

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Genetic Polymorphism of Thiopurine S-Methyltransferase: Molecular Mechanisms and Clinical Importance von Krynetski, Eugene Y., Evans, William E.

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Msh2 Deficiency Attenuates But Does Not Abolish Thiopurine Hematopoietic Toxicity in Msh2-/- Mice von Krynetskaia, Natalia F, Brenner, Timothy L, Krynetski, Eugene Y, Du, Weinan, Panetta, John C, Ching-Hon, Pui, Evans, William E

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A Single Point Mutation Leading to Loss of Catalytic Activity in Human Thiopurine S-Methyltransferase von Krynetski, Eugene Y., Schuetz, John D., Galpin, Amy J., Pui, Ching-Hon, Relling, Mary V., Evans, William E.

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TPMT genetic variations in populations of the Russian Federation von Samochatova, Elena V., Chupova, Natalia V., Rudneva, Anastassia, Makarova, Olga, Nasedkina, Tatyana V., Fedorova, Olga E., Glotov, Andrei S., Kozhekbaeva, Zh, Maiorova, Olga A., Roumyantsev, Alexander G., Krynetski, Eugene Y., Krynetskaia, Natalia F., Evans, William E., Ribeiro, Raul C.

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A Novel Protein Complex Distinct from Mismatch Repair Binds Thioguanylated DNA von Krynetski, E Y, Krynetskaia, N F, Gallo, A E, Murti, K G, Evans, W E

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Human RNase H-Mediated RNA Cleavage from DNA-RNA Duplexes Is Inhibited by 6-Deoxythioguanosine Incorporation into DNA von Krynetskaia, N F, Krynetski, E Y, Evans, W E

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Thioguanine substitution alters DNA cleavage mediated by topoisomerase II von Krynetskaia, Natalia F., Cai, Xiangjun, Nitiss, John L., Krynetski, Eugene Y., Relling, Mary V.

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Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus von Relling, Mary V., Hancock, Michael L., Rivera, Gaston K., Sandlund, John T., Ribeiro, Raul C., Krynetski, Eugene Y., Pui, Ching-Hon, Evans, William E.

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Promoter and intronic sequences of the human thiopurine S-methyltransferase (TPMT) gene isolated from a human PAC1 genomic library von KRYNETSKI, E. Y, FESSING, M. Y, YATES, C. R, SUN, D, SCHUETZ, J. D, EVANS, W. E

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Deoxythioguanosine triphosphate impairs HIV replication: a new mechanism for an old drug von KRYNETSKAIA, NATALIA F., FENG, JOY Y., KRYNETSKI, EUGENE Y., GARCIA, J. VICTOR, PANETTA, JOHN C., ANDERSON, KAREN S., EVANS, WILLIAM E.

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Molecular haplotyping of genomic DNA for multiple single-nucleotide polymorphisms located kilobases apart using long-range polymerase chain reaction and intramolecular ligation von MCDONALD, Oliver G, KRYNETSKI, Eugene Y, EVANS, William E

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Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells von DERVIEUX, Thierry, BLANCO, Javier G, KRYNETSKI, Eugene Y, VANIN, Elio F, ROUSSEL, Martine F, RELLING, Mary V

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Thiopurine S-methyltransferase deficiency : Two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians von HUNG-LIANG TAI, KRYNETSKI, E. Y, YATES, C. R, LOENNECHEN, T, FESSING, M. Y, KRYNETSKAIA, N. F, EVANS, W. E

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