How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases? von Jorda, Radek, Hendrychová, Denisa, Voller, Jiří, Řezníčková, Eva, Gucký, Tomáš, Kryštof, Vladimír

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How selective are clinical CDK4/6 inhibitors? von Hendrychová, Denisa, Jorda, Radek, Kryštof, Vladimír

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Design, Synthesis and In Vitro Activity of Anticancer Styrylquinolines. The p53 Independent Mechanism of Action von Mrozek-Wilczkiewicz, Anna, Spaczynska, Ewelina, Malarz, Katarzyna, Cieslik, Wioleta, Rams-Baron, Marzena, Kryštof, Vladimír, Musiol, Robert

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Strategies for overcoming resistance to Bruton's tyrosine kinase inhibitor zanubrutinib von Dostálová, Hana, Kryštof, Vladimír

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Adamantane-Substituted Purine Nucleosides: Synthesis, Host-Guest Complexes with β-Cyclodextrin and Biological Activity von Rudolfová, Jana, Kryštof, Vladimír, Nečas, Marek, Vícha, Robert, Rouchal, Michal

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Synthesis, Bacteriostatic and Anticancer Activity of Novel Phenanthridines Structurally Similar to Benzo[c]phenanthridine Alkaloids von Lasák, Pavel, Motyka, Kamil, Kryštof, Vladimír, Stýskala, Jakub

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Anticancer dinuclear Ir(III) complex activates Nrf2 and interferes with NAD(H) in cancer cells von Řezníčková, Eva, Bárta, Ondřej, Milde, David, Kryštof, Vladimír, Štarha, Pavel

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1,4,6-Trisubstituted imidazo[4,5-c]pyridines as inhibitors of Bruton’s tyrosine kinase von Krajčovičová, Soňa, Jorda, Radek, Vanda, David, Soural, Miroslav, Kryštof, Vladimír

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Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2‑b]pyridazine Derivatives Identified by Scaffold Hopping von Břehová, Petra, Řezníčková, Eva, Škach, Kryštof, Jorda, Radek, Dejmek, Milan, Vojáčková, Veronika, Šála, Michal, Kovalová, Markéta, Dračínský, Martin, Dolníková, Alexandra, Strmeň, Timotej, Kinnertová, Monika, Chalupský, Karel, Dvořáková, Alexandra, Gucký, Tomáš, Mertlíková Kaiserová, Helena, Klener, Pavel, Nencka, Radim, Kryštof, Vladimír

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Adamantane-Substituted Purines and Their β-Cyclodextrin Complexes: Synthesis and Biological Activity von Rouchal, Michal, Rudolfová, Jana, Kryštof, Vladimír, Vojáčková, Veronika, Čmelík, Richard, Vícha, Robert

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Modulation of FLT3-ITD and CDK9 in acute myeloid leukaemia cells by novel proteolysis targeting chimera (PROTAC) von Řezníčková, Eva, Krajčovičová, Soňa, Peřina, Miroslav, Kovalová, Markéta, Soural, Miroslav, Kryštof, Vladimír

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Anticancer effect of zanubrutinib in HER2-positive breast cancer cell lines von Dostálová, Hana, Jorda, Radek, Řezníčková, Eva, Kryštof, Vladimír

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Scaffold hopping of the SYK inhibitor entospletinib leads to broader targeting of the BCR signalosome von Jorda, Radek, Krajčovičová, Soňa, Králová, Petra, Soural, Miroslav, Kryštof, Vladimír

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3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insight... von Abo-Ashour, Mahmoud F., Eldehna, Wagdy M., Nocentini, Alessio, Bonardi, Alessandro, Bua, Silvia, Ibrahim, Hany S., Elaasser, Mahmoud M., Kryštof, Vladimír, Jorda, Radek, Gratteri, Paola, Abou-Seri, Sahar M., Supuran, Claudiu T.

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One-pot three-component synthesis of novel pyrazolo[3,4-b]pyridines as potent antileukemic agents von Barghash, Reham F., Eldehna, Wagdy M., Kovalová, Markéta, Vojáčková, Veronika, Kryštof, Vladimír, Abdel-Aziz, Hatem A.

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Identification of novel dithiocarbamate-copper complexes targeting p97/NPL4 pathway in cancer cells von Loffelmann, Martin, Škrott, Zdeněk, Majera, Dušana, Štarha, Pavel, Kryštof, Vladimír, Mistrík, Martin

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Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors von Vlková, Kristýna, Gucký, Tomáš, Peřina, Miroslav, Řezníčková, Eva, Kryštof, Vladimír

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A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors von Gucký, Tomáš, Jorda, Radek, Zatloukal, Marek, Bazgier, Václav, Berka, Karel, Řezníčková, Eva, Béres, Tibor, Strnad, Miroslav, Kryštof, Vladimír

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A Stepwise Approach for the Synthesis of Folic Acid Conjugates with Protein Kinase Inhibitors von Krajčovičová, Soňa, Gucký, Tomáš, Hendrychová, Denisa, Kryštof, Vladimír, Soural, Miroslav

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Synthesis and biological activity evaluation of novel 3,5,7-trisubstituted pyrazolo[1,5-a]pyrimidines von Vlková, Kristýna, Padrtová, Růžena, Gucký, Tomáš, Peřina, Miroslav, Řezníčková, Eva, Kryštof, Vladimír

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