Potent Inhibitors of the Hedgehog Signaling Pathway von Brunton, Shirley A, Stibbard, John H. A, Rubin, Lee L, Kruse, Lawrence I, Guicherit, Oivin M, Boyd, Edward A, Price, Steven

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Potent agonists of the Hedgehog signaling pathway von Brunton, Shirley A., Stibbard, John H.A., Rubin, Lee L., Guicherit, Oivin M., Kruse, Lawrence I., Price, Stephen, di Lucrezia, Raffaella, MacKinnon, Colin H., Avery, Alaric, Park, Yvonne, Buxton, Danielle, Boyd, Edward A

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Enantiospecific synthesis of (-)-tabtoxinine .beta.-lactam von Dolle, Roland E, Li, Chun Sing, Novelli, Riccardo, Kruse, Lawrence I, Eggleston, Drake

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The copper sites of dopamine .beta.-hydroxylase: an x-ray absorption spectroscopic study von Scott, Robert A, Sullivan, Richard J, DeWolf, Walter E, Dolle, Roland E, Kruse, Lawrence I

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Inactivation of dopamine .beta.-hydroxylase by p-cresol: isolation and characterization of covalently modified active site peptides von DeWolf, Walter E, Carr, Steven A, Varrichio, Angela, Goodhart, Paula J, Mentzer, Mary A, Roberts, Gerald D, Southan, Christopher, Dolle, Roland E, Kruse, Lawrence I

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Ergoline synthons. 2. Synthesis of 1,5-dihydrobenz[cd]indol-4(3H)-ones and 1,3,4,5-tetrahydrobenz[cd]indol-4-amines von Kruse, Lawrence I, Meyer, Michael D

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Inactivation of dopamine .beta.-hydroxylase by .beta.-ethynyltyramine: kinetic characterization and covalent modification of an active site peptide von DeWolf, Walter E, Chambers, Pamela A, Southan, Christopher, Saunders, David, Kruse, Lawrence I

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Multisubstrate inhibitors of dopamine .beta.-hydroxylase. 1. Some 1-phenyl and 1-phenyl-bridged derivatives of imidazole-2-thione von Kruse, Lawrence I, Kaiser, Carl, DeWolf, Walter E, Frazee, James S, Garvey, Eleanor, Hilbert, Eileen L, Faulkner, Wayne A, Flaim, Kathryn E, Sawyer, John L, Berkowitz, Barry A

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Studies on the acid-catalyzed homonuclear steroidal diene isomerization von Dolle, Roland E, Schmidt, Stanley J, Eggleston, Drake, Kruse, Lawrence I

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Synthesis and tubulin binding of 4'-(1-azi-2,2,2-trifluoroethyl)oncodazole, a photolabile analog of oncodazole von Ladd, David L, Harrsch, Peter B, Kruse, Lawrence I

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Synthesis of .beta.,.gamma.-unsaturated amino acids von Baldwin, Jack E, Haber, Stephen B, Hoskins, Carolyn, Kruse, Lawrence I

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Aromatic acylation/reduction: an efficient Friedel-Crafts alkylation reaction von JAXA-CHAMIEC, A, SHAH, V. P, KRUSE, L. I

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6,7-Dichloro-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline. A structurally novel .beta.-adrenergic receptor blocking agent von Kaiser, Carl, Oh, Hye Ja, Garcia-Slanga, Blanche J, Sulpizio, Anthony C, Hieble, J. Paul, Wawro, Joyce E, Kruse, Lawrence I

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Synthesis of Novel Thiol-Containing Citric Acid Analogs. Kinetic Evaluation of These and Other Potential Active-Site-Directed and Mechanism-Based Inhibitors of ATP Citrate Lyase von Dolle, Roland E, Gribble, Andy, Wilkes, Tracey, Kruse, Lawrence I, Eggleston, Drake, Saxty, Barbara A, Wells, Timothy N. C, Groot, Pieter H. E

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Total synthesis of antitumor agent AT-125, (.alpha.S,5S)-.alpha.-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid von Baldwin, Jack E, Kruse, Lawrence I, Cha, Jin-Kun

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Rules for ring closure: ring formation by conjugate addition of oxygen nucleophiles von Baldwin, Jack E., Thomas, Richard C., Kruse, Lawrence I., Silberman, Lee

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Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs von Kruse, Lawrence I, Ladd, David L, Harrsch, Peter B, McCabe, Francis L, Mong, Shau Ming, Faucette, Leo, Johnson, Randall

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Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine .beta.-hydroxylase. 4. Structure-activ... von Kruse, Lawrence I, Kaiser, Carl, DeWolf, Walter E, Finkelstein, Joseph A, Frazee, James S, Hilbert, Eileen L, Ross, Stephen T, Flaim, Kathryn E, Sawyer, John L

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ATP-citrate-lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-.beta.-lactam containing analogs of citric acid as potential tight-binding inhibitors von Dolle, Roland E, McNair, David, Hughes, Mark J, Kruse, Lawrence I, Eggelston, Drake, Saxty, Barbara A, Wells, Timothy N. C, Groot, Pieter H. E

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Ergoline synthons: Synthesis of 3,4-dihydro-6-methoxybenz[cd]indol-5(1H)-one (6-methoxy-Uhle's ketone) and 3,4-dihydrobenz[cd]indol-5(1H)-one (Uhle's ketone) via a novel decarboxyl... von Meyer, Michael D, Kruse, Lawrence I

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