FoxO Transcription Factors Are Critical Regulators of Diabetes-Related Muscle Atrophy von O'Neill, Brian T, Bhardwaj, Gourav, Penniman, Christie M, Krumpoch, Megan T, Suarez Beltran, Pablo A, Klaus, Katherine, Poro, Kennedy, Li, Mengyao, Pan, Hui, Dreyfuss, Jonathan M, Nair, K Sreekumaran, Kahn, C Ronald

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Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function von Boucher, Jeremie, Softic, Samir, El Ouaamari, Abdelfattah, Krumpoch, Megan T, Kleinridders, Andre, Kulkarni, Rohit N, O'Neill, Brian T, Kahn, C Ronald

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Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis von O'Neill, Brian T, Lee, Kevin Y, Klaus, Katherine, Softic, Samir, Krumpoch, Megan T, Fentz, Joachim, Stanford, Kristin I, Robinson, Matthew M, Cai, Weikang, Kleinridders, Andre, Pereira, Renata O, Hirshman, Michael F, Abel, E Dale, Accili, Domenico, Goodyear, Laurie J, Nair, K Sreekumaran, Kahn, C Ronald

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595 Inhibition of integrin αvβ8 in combination with low dose radiation induces antitumor effect in advanced immune checkpoint blockade refractory tumor model von Reszka-Blanco, Natalia, Krumpoch, Megan, Mentzer, Michaela, Yadav, Vinod Yadav, Bannister, Brianna, Cui, Dan, Konopka, Elizabeth, Lee, Dooyoung, Lin, Fu-Yang, Moy, Terence, Nebelitsky, Eugene, Qiao, Qi, Smutske, Inese, Root, Charlotte, Allison, Patrick, Krueger, Sarah, Troast, Dawn, Lippa, Blaise, Rogers, Bruce, Ray, Adrian

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A selective antibiotic for Lyme disease von Leimer, Nadja, Wu, Xiaoqian, Imai, Yu, Morrissette, Madeleine, Pitt, Norman, Favre-Godal, Quentin, Iinishi, Akira, Jain, Samta, Caboni, Mariaelena, Leus, Inga V., Bonifay, Vincent, Niles, Samantha, Bargabos, Rachel, Ghiglieri, Meghan, Corsetti, Rachel, Krumpoch, Megan, Fox, Gabriel, Son, Sangkeun, Klepacki, Dorota, Polikanov, Yury S., Freliech, Cecily A., McCarthy, Julie E., Edmondson, Diane G., Norris, Steven J., D’Onofrio, Anthony, Hu, Linden T., Zgurskaya, Helen I., Lewis, Kim

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Abstract 1559: Inhibition of integrin αvβ8 enhances immune checkpoint induced anti-tumor immunity by acting across immunologic synapse in syngeneic models of breast cancer von Reszka-Blanco, Natalia J., Yadav, Vinod, Krumpoch, Megan, Cappellucci, Laura, Cui, Dan, Dowling, James E., Gwara, Elizabeth, Harrison, Bryce, Lee, Dooyoung, Lin, Fu-Yang, Luus, Lia, Monroy, Meghan, Moy, Terence I., Nebelitsky, Eugene, Qiao, Qi, Sullivan, Andrew, Troast, Dawn, Lippa, Blaise, Rogers, Bruce, Ray, Adrian S.

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Modeling relationship of pharmacokinetics, in vitro potency, and α4β7 receptor occupancy with intestinal cell trafficking in a gut-homing mouse model of IBD with MORF-057 von Redhu, Naresh S., Hussain, Ali, Srinivasan, Sathish, Lee, Dooyoung, Bannister, Brianna, Blanco, Natalia, Bonesteel, Raegan, Camblin, Adam, Cappellucci, Laura, Cohen, Rhianna, Harrison, Bryce, Hahn, Kristopher N, Kim, Kwangsoo, Krumpoch, Megan, Lin, Fu-Yang, McManus, Kevin, McShea, Molly, Pondish, Jessica, Linde, Peter, Lugovskoy, Alex, Mangada, Maloy, Moy, Terence I., Sang, Allison, Gelais, Sarah St, Sullivan, Andrew, Troast, Dawn, Zhong, Cheng, Wang, Liangsu, Cui, Dan, Bursavich, Matthew G., Lippa, Blaise, Rogers, Bruce N., Ray, Adrian S., Wong, Jamie

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Tu1283 PRECLINICAL CHARACTERIZATION OF AN ORAL SMALL MOLECULE INHIBITOR TARGETING THE INTEGRIN α4β7 FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASES (IBD) von Wong, Jamie, Bursavich, Matthew, Blanco, Natalia, Camblin, Adam, Cappellucci, Laura, Cohen, Rhianna, Cui, Dan, Hahn, Kris, Krumpoch, Megan, Lee, Dooyoung, Lin, Fu-Yang, Lippa, Blaise, Lugovskoy, Alex, McShea, Molly, Mangada, Maloy, Mostafavi, Siavash, Moy, Terence, Ray, Adrian S., Redhu, Naresh Singh, Sang, Allison, Sullivan, Andrew, Traber, Peter G., Troast, Dawn, Zhong, Cheng, Wang, Liangsu, Rogers, Bruce N.

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