Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial von Tarcha, Eric J, Olsen, Chelsea M, Probst, Peter, Peckham, David, Muñoz-Elías, Ernesto J, Kruger, James G, Iadonato, Shawn P

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A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC von Mohammad, Helai P., Smitheman, Kimberly N., Kamat, Chandrashekhar D., Soong, David, Federowicz, Kelly E., Van Aller, Glenn S., Schneck, Jess L., Carson, Jeffrey D., Liu, Yan, Butticello, Michael, Bonnette, William G., Gorman, Shelby A., Degenhardt, Yan, Bai, Yuchen, McCabe, Michael T., Pappalardi, Melissa B., Kasparec, Jiri, Tian, Xinrong, McNulty, Kenneth C., Rouse, Meagan, McDevitt, Patrick, Ho, Thau, Crouthamel, Michelle, Hart, Timothy K., Concha, Nestor O., McHugh, Charles F., Miller, William H., Dhanak, Dashyant, Tummino, Peter J., Carpenter, Christopher L., Johnson, Neil W., Hann, Christine L., Kruger, Ryan G.

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Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia von Bell, Charles C., Fennell, Katie A., Chan, Yih-Chih, Rambow, Florian, Yeung, Miriam M., Vassiliadis, Dane, Lara, Luis, Yeh, Paul, Martelotto, Luciano G., Rogiers, Aljosja, Kremer, Brandon E., Barbash, Olena, Mohammad, Helai P., Johanson, Timothy M., Burr, Marian L., Dhar, Arindam, Karpinich, Natalie, Tian, Luyi, Tyler, Dean S., MacPherson, Laura, Shi, Junwei, Pinnawala, Nathan, Yew Fong, Chun, Papenfuss, Anthony T., Grimmond, Sean M., Dawson, Sarah-Jane, Allan, Rhys S., Kruger, Ryan G., Vakoc, Christopher R., Goode, David L., Naik, Shalin H., Gilan, Omer, Lam, Enid Y. N., Marine, Jean-Christophe, Prinjha, Rab K., Dawson, Mark A.

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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27) von McCabe, Michael T, Graves, Alan P, Ganji, Gopinath, Diaz, Elsie, Halsey, Wendy S, Jiang, Yong, Smitheman, Kimberly N, Ott, Heidi M, Pappalardi, Melissa B, Allen, Kimberly E, Chen, Stephanie B, Della Pietra, Anthony III, Dul, Edward, Hughes, Ashley M, Gilbert, Seth A, Thrall, Sara H, Tummino, Peter J, Kruger, Ryan G, Brandt, Martin, Schwartz, Benjamin, Creasy, Caretha L

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Effect of nozzle selection on deposition of thiamethoxam in Actara® spray drift and implications for off-field risk assessment von Perine, J., Anderson, J.C., Kruger, G.R., Abi-Akar, F., Overmyer, J.

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Design of Ionic Liquid 3-Methyl-1-sulfonic Acid Imidazolium Nitrate as Reagent for the Nitration of Aromatic Compounds by in Situ Generation of NO2 in Acidic Media von Zolfigol, Mohammad A, Khazaei, Ardeshir, Moosavi-Zare, Ahmad R, Zare, Abdolkarim, Kruger, Hendrik G, Asgari, Zhila, Khakyzadeh, Vahid, Kazem-Rostami, Masoud

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Enantioselective Organocatalyzed Transformations of β‑Ketoesters von Govender, Thavendran, Arvidsson, Per I, Maguire, Glenn E. M, Kruger, Hendrik G, Naicker, Tricia

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Interrogating the lack of diversity of thought in the pandemic response that led to mistakes - holistic evidence-based approach to deal with future pandemics von Aldous, Colleen, Kruger, Hendrik G

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Targeting Histone Methylation in Cancer von McCabe, Michael T, Mohammad, Helai P, Barbash, Olena, Kruger, Ryan G

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Crystal, spectroscopic and quantum mechanics studies of Schiff bases derived from 4-nitrocinnamaldehyde von Ani, Friday E., Ibeji, Collins U., Obasi, Nnamdi L., Kelani, Monsuru T., Ukogu, Kingsley, Tolufashe, Gideon F., Ogundare, Segun A., Oyeneyin, Oluwatoba E., Maguire, Glenn E. M., Kruger, Hendrik G.

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The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study von Md Abdur Rauf, Shah, Arvidsson, Per I, Albericio, Fernando, Govender, Thavendran, Maguire, Glenn E M, Kruger, Hendrik G, Honarparvar, Bahareh

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A Synthesis of “Dual Warhead” β‑Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β‑Sultams von Chinthakindi, Praveen K, Govender, Kimberleigh B, Kumar, A. Sanjeeva, Kruger, Hendrik G, Govender, Thavendran, Naicker, Tricia, Arvidsson, Per I

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Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all- trans retinoic acid in acute myeloid leukemia across sub... von Smitheman, Kimberly N, Severson, Tesa M, Rajapurkar, Satyajit R, McCabe, Michael T, Karpinich, Natalie, Foley, James, Pappalardi, Melissa B, Hughes, Ashley, Halsey, Wendy, Thomas, Elizabeth, Traini, Christopher, Federowicz, Kelly E, Laraio, Jenny, Mobegi, Fredrick, Ferron-Brady, Geraldine, Prinjha, Rabinder K, Carpenter, Christopher L, Kruger, Ryan G, Wessels, Lodewyk, Mohammad, Helai P

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Assembly of the SIR Complex and Its Regulation by O-Acetyl-ADP-Ribose, a Product of NAD-Dependent Histone Deacetylation von Liou, Gunn-Guang, Tanny, Jason C., Kruger, Ryan G., Walz, Thomas, Moazed, Danesh

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Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation von Van Aller, Glenn S, Reynoird, Nicolas, Barbash, Olena, Huddleston, Michael, Liu, Shichong, Zmoos, Anne-Flore, McDevitt, Patrick, Sinnamon, Robert, Le, BaoChau, Mas, Gloria, Annan, Roland, Sage, Julien, Garcia, Benjamin A, Tummino, Peter J, Gozani, Or, Kruger, Ryan G

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Concerted hydrolysis mechanism of HIV-1 natural substrate against subtypes B and C-SA PR: insight through molecular dynamics and hybrid QM/MM studies von Sanusi, Zainab K, Lawal, Monsurat M, Govender, Thavendran, Baijnath, Sooraj, Naicker, Tricia, Maguire, Glenn E. M, Honarparvar, Bahareh, Kruger, Hendrik G

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Evaluating the Performance of a Non-Bonded Cu2+Model Including Jahn-Teller Effect into the Binding of Tyrosinase Inhibitors von Martins, Lucas Sousa, Lameira, Jeronimo, Kruger, Hendrik G., Alves, Claudio Nahum, Silva, Jose Rogerio A.

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Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2 von Verma, Sharad K, Tian, Xinrong, LaFrance, Louis V, Duquenne, Céline, Suarez, Dominic P, Newlander, Kenneth A, Romeril, Stuart P, Burgess, Joelle L, Grant, Seth W, Brackley, James A, Graves, Alan P, Scherzer, Daryl A, Shu, Art, Thompson, Christine, Ott, Heidi M, Aller, Glenn S. Van, Machutta, Carl A, Diaz, Elsie, Jiang, Yong, Johnson, Neil W, Knight, Steven D, Kruger, Ryan G, McCabe, Michael T, Dhanak, Dashyant, Tummino, Peter J, Creasy, Caretha L, Miller, William H

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68Ga Radiolabeling of NODASA‐Functionalized Phage Display–Derived Peptides for Prospective Assessment as Tuberculosis‐Specific PET Radiotracers von Gouws, Christiaan A., Naicker, Tricia, Torre, Beatriz G., Albericio, Fernando, Duvenhage, Janie, Kruger, Hendrik G., Marjanovic‐Painter, Biljana, Mdanda, Sipho, Zeevaart, Jan R., Ebenhan, Thomas, Govender, Thavendran

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On-Water Synthesis of Biaryl Sulfonyl Fluorides von Chinthakindi, Praveen K, Kruger, Hendrik G, Govender, Thavendran, Naicker, Tricia, Arvidsson, Per I

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