EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma von Struve, Nina, Binder, Zev A., Stead, Lucy F., Brend, Tim, Bagley, Stephen J., Faulkner, Claire, Ott, Leonie, Müller-Goebel, Justus, Weik, Anna-Sophie, Hoffer, Konstantin, Krug, Leonie, Rieckmann, Thorsten, Bußmann, Lara, Henze, Marvin, Morrissette, Jennifer J. D., Kurian, Kathreena M., Schüller, Ulrich, Petersen, Cordula, Rothkamm, Kai, O´ Rourke, Donald M., Short, Susan C., Kriegs, Malte

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A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells von Köcher, Sabrina, Zech, Henrike Barbara, Krug, Leonie, Gatzemeier, Fruzsina, Christiansen, Sabrina, Meyer, Felix, Rietow, Ruth, Struve, Nina, Mansour, Wael Yassin, Kriegs, Malte, Petersen, Cordula, Betz, Christian, Rothkamm, Kai, Rieckmann, Thorsten

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Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities von Struve, Nina, Hoffer, Konstantin, Weik, Anna-Sophie, Riepen, Britta, Krug, Leonie, Cetin, Meryem H, Burmester, Jasmin, Ott, Leonie, Liebing, Jana, Gatzemeier, Fruzsina, Müller-Goebel, Justus, Gerbach, Mirja, Bußmann, Lara, Parplys, Ann Christin, Unger, Kristian, Mansour, Wael Y, Schüller, Ulrich, Rieckmann, Thorsten, Petersen, Cordula, Rothkamm, Kai, Short, Susan C, Kriegs, Malte

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Abstract B44: Identification of epigenomic changes induced by H3 K27M mutation in glioblastoma using patient-derived and CRISPR/Cas9 edited cell lines von Harutyunyan, Ashot S., Krug, Brian, Papillon-Cavanagh, Simon, Chen, Haifen, Deshmukh, Shriya, Cheung, Warren A., Li, Rui, Belle, Jad, Bechet, Denise, Jay, Nicolas De, Zeinieh, Michele, Gayden, Tenzin, Russo, Caterina, Mikael, Leonie, Faury, Damien, Kleinman, Claudia, Pastinen, Tomi, Majewski, Jacek, Jabado, Nada

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Synthetic Lethality Screen Identifies RPS6KA2 as Modifier of Epidermal Growth Factor Receptor Activity in Pancreatic Cancer von Milosevic, Nada, Kühnemuth, Benjamin, Mühlberg, Leonie, Ripka, Stefanie, Griesmann, Heidi, Lölkes, Carolin, Buchholz, Malte, Aust, Daniela, Pilarsky, Christian, Krug, Sebastian, Gress, Thomas, Michl, Patrick

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Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas von Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

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H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis von Harutyunyan, Ashot S., Krug, Brian, Chen, Haifen, Papillon-Cavanagh, Simon, Zeinieh, Michele, De Jay, Nicolas, Deshmukh, Shriya, Chen, Carol C. L., Belle, Jad, Mikael, Leonie G., Marchione, Dylan M., Li, Rui, Nikbakht, Hamid, Hu, Bo, Cagnone, Gael, Cheung, Warren A., Mohammadnia, Abdulshakour, Bechet, Denise, Faury, Damien, McConechy, Melissa K, Pathania, Manav, Jain, Siddhant U., Ellezam, Benjamin, Weil, Alexander G., Montpetit, Alexandre, Salomoni, Paolo, Pastinen, Tomi, Lu, Chao, Lewis, Peter W., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Majewski, Jacek

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Stalled developmental programs at the root of pediatric brain tumors von Jessa, Selin, Blanchet-Cohen, Alexis, Krug, Brian, Vladoiu, Maria, Coutelier, Marie, Faury, Damien, Poreau, Brice, De Jay, Nicolas, Hébert, Steven, Monlong, Jean, Farmer, W. Todd, Donovan, Laura K., Hu, Yixing, McConechy, Melissa K., Cavalli, Florence M. G., Mikael, Leonie G., Ellezam, Benjamin, Richer, Maxime, Allaire, Andréa, Weil, Alexander G., Atkinson, Jeffrey, Farmer, Jean-Pierre, Dudley, Roy W. R., Larouche, Valerie, Crevier, Louis, Albrecht, Steffen, Filbin, Mariella G., Sartelet, Hervé, Lutz, Pierre-Eric, Nagy, Corina, Turecki, Gustavo, Costantino, Santiago, Dirks, Peter B., Murai, Keith K., Bourque, Guillaume, Ragoussis, Jiannis, Garzia, Livia, Taylor, Michael D., Jabado, Nada, Kleinman, Claudia L.

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Cause-and-Effect Analysis as a Tool To Improve the Reproducibility of Nanobioassays: Four Case Studies von Petersen, Elijah J, Hirsch, Cordula, Elliott, John T, Krug, Harald F, Aengenheister, Leonie, Arif, Ali Talib, Bogni, Alessia, Kinsner-Ovaskainen, Agnieszka, May, Sarah, Walser, Tobias, Wick, Peter, Roesslein, Matthias

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Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing von Wittner, Leonie, Wagener, Lukas, Wiese, Jakob J, Stolzer, Iris, Krug, Susanne M, Naschberger, Elisabeth, Jackstadt, Rene, Beyaert, Rudi, Atreya, Raja, Kühl, Anja A, Sturm, Gregor, Gonzalez-Acera, Miguel, Patankar, Jay V, Becker, Christoph, Siegmund, Britta, Trajanoski, Zlatko, Winner, Beate, Neurath, Markus F, Schumann, Michael, Günther, Claudia

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The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia von Angenendt, Linus, Bormann, Eike, Pabst, Caroline, Alla, Vijay, Görlich, Dennis, Braun, Leonie, Dohlich, Kim, Schwöppe, Christian, Bohlander, Stefan K., Arteaga, Maria Francisca, Wethmar, Klaus, Hartmann, Wolfgang, Angenendt, Adrian, Kessler, Torsten, Mesters, Rolf M., Stelljes, Matthias, Rothenberg-Thurley, Maja, Spiekermann, Karsten, Hébert, Josée, Sauvageau, Guy, Valk, Peter J. M., Löwenberg, Bob, Serve, Hubert, Müller-Tidow, Carsten, Lenz, Georg, Wörmann, Bernhard J., Sauerland, M. Christina, Hiddemann, Wolfgang, Berdel, Wolfgang E., Krug, Utz, Metzeler, Klaus H., Mikesch, Jan-Henrik, Herold, Tobias, Schliemann, Christoph

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Lattice-commensurate skyrmion texture in a centrosymmetric breathing kagome magnet von Hirschberger, Max, Szigeti, Bertalan G., Hemmida, Mamoun, Hirschmann, Moritz M., Esser, Sebastian, Ohsumi, Hiroyuki, Tanaka, Yoshikazu, Spitz, Leonie, Gao, Shang, Kolincio, Kamil K., Sagayama, Hajime, Nakao, Hironori, Yamasaki, Yuichi, Forró, László, Krug von Nidda, Hans-Albrecht, Kezsmarki, Istvan, Arima, Taka-hisa, Tokura, Yoshinori

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Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas von Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

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Proteolytic activity of the paracaspase MALT1 is involved in epithelial restitution and mucosal healing von Wittner, Leonie, Wagener, Lukas, Wiese, Jakob J, Stolzer, Iris, Krug, Susanne M, Naschberger, Elisabeth, Jackstadt, Rene, Beyaert, Rudi, Atreya, Raja, Kühl, Anja A, Sturm, Gregor, Gonzalez-Acera, Miguel, Patankar, Jay V, Becker, Christoph, Siegmund, Britta, Trajanoski, Zlatko, Winner, Beate, Neurath, Markus F, Schumann, Michael, Günther, Claudia

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Atezolizumab Plus Bevacizumab in Patients with Advanced and Progressing Hepatocellular Carcinoma: Retrospective Multicenter Experience von Sinner, Friedrich, Pinter, Matthias, Scheiner, Bernhard, Ettrich, Thomas Jens, Sturm, Niklas, Gonzalez-Carmona, Maria A, Waidmann, Oliver, Finkelmeier, Fabian, Himmelsbach, Vera, De Toni, Enrico N, Ben Khaled, Najib, Mohr, Raphael, Fründt, Thorben Wilhelm, Kütting, Fabian, Bömmel, Florian van, Lieb, Sabine, Krug, Sebastian, Bettinger, Dominik, Schultheiß, Michael, Jochheim, Leonie S, Best, Jan, Müller, Christian, Keitel, Verena, Venerito, Marino

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Improving cooperation between general practitioners and dermatologists via telemedicine: study protocol of the cluster-randomized controlled TeleDerm study von Koch, Roland, Polanc, Andreas, Haumann, Hannah, Kirtschig, Gudula, Martus, Peter, Thies, Christian, Sundmacher, Leonie, Gaa, Carmen, Witkamp, Leonard, Joos, Stefanie

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CUX1: a modulator of tumour aggressiveness in pancreatic neuroendocrine neoplasms von Krug, Sebastian, Kühnemuth, Benjamin, Griesmann, Heidi, Neesse, Albrecht, Mühlberg, Leonie, Boch, Michael, Kortenhaus, Juliane, Fendrich, Volker, Wiese, Dominik, Sipos, Bence, Friemel, Juliane, Gress, Thomas M, Michl, Patrick

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miRNA dynamics in tumor-infiltrating myeloid cells modulating tumor progression in pancreatic cancer von Mühlberg, Leonie, Kühnemuth, Benjamin, Costello, Eithne, Shaw, Victoria, Sipos, Bence, Huber, Magdalena, Griesmann, Heidi, Krug, Sebastian, Schober, Marvin, Gress, Thomas M., Michl, Patrick

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Von Umwelt zu Corona: Der Schwerpunktwechsel in der Berichterstattung während der ersten Welle der Coronapandemie in Deutschland von Krug, Maximilian, Kuhn, Paula, Lauschner, Leonie, Mercsak, Aylin, Schulte-Zweckel, Nora

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Denkmalpflege als kulturelle Praxis – Zwischen Wirklichkeit und Anspruch«. Jahrestagung der Vereinigung der Landesdenkmalpfleger in der Bundesrepublik Deutschland in Oldenburg (18.... von Brinkmann, Dominik, Fritzvon Preuschen, Markus, Gerner-Beuerle, Claudia, Häret-Krug, Katinka, Kaiser, Roswitha, Klinkner, Esther, Köhren, Leonie, Weber, Ulrike

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