Discovery of ABT-267, a Pan-Genotypic Inhibitor of HCV NS5A von DeGoey, David A., Randolph, John T., Liu, Dachun, Pratt, John, Hutchins, Charles, Donner, Pamela, Krueger, A. Chris, Matulenko, Mark, Patel, Sachin, Motter, Christopher E., Nelson, Lissa, Keddy, Ryan, Tufano, Michael, Caspi, Daniel D., Krishnan, Preethi, Mistry, Neeta, Koev, Gennadiy, Reisch, Thomas J., Mondal, Rubina, Pilot-Matias, Tami, Gao, Yi, Beno, David W. A., Maring, Clarence J., Molla, Akhter, Dumas, Emily, Campbell, Andrew, Williams, Laura, Collins, Christine, Wagner, Rolf, Kati, Warren M.

Volltext

Discovery of 2-aminoisobutyric acid ethyl ester (AIBEE) phosphoramidate prodrugs for delivering nucleoside HCV NS5B polymerase inhibitors von Randolph, John T., Li, Tongmei, Chris Krueger, A., Heyman, Howard R., Chen, Hui-Ju, Bow, Daniel A.J., Van Handel, Cecilia, Peterkin, Vincent, Carr, Robert A., Stolarik, DeAnne, Dekhtyar, Tatyana, Irvin, Michelle, Krishnan, Preethi, Wagner, Rolf, DeGoey, David A.

Volltext

Synthesis and evaluation of 2′-dihalo ribonucleotide prodrugs with activity against hepatitis C virus von Chris Krueger, A., Chen, Hui-Ju, Randolph, John T., Brown, Brian S., Halvorsen, Geoff T., Heyman, Howard R., Li, Tongmei, Marvin, Christopher C., Shanley, Jason P., Voight, Eric A., Bow, Daniel A.J., Van Handel, Cecilia, Peterkin, Vincent, Carr, Robert A., Stolarik, DeAnne, Dekhtyar, Tatyana, Irvin, Michelle L., Krishnan, Preethi, Henry, Rodger F., Wagner, Rolf, DeGoey, David A.

Volltext

Novel Hepatitis C virus replicon inhibitors: Synthesis and structure–activity relationships of fused pyrimidine derivatives von Chris Krueger, A., Madigan, Darold L., Beno, David W., Betebenner, David A., Carrick, Robert, Green, Brian E., He, Wenping, Liu, Dachun, Maring, Clarence J., McDaniel, Keith F., Mo, Hongmei, Molla, Akhteruzzaman, Motter, Christopher E., Pilot-Matias, Tami J., Tufano, Michael D., Kempf, Dale J.

Volltext

Highlights of the Structure–Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530) von Wagner, Rolf, Randolph, John T, Patel, Sachin V, Nelson, Lissa, Matulenko, Mark A, Keddy, Ryan, Pratt, John K, Liu, Dachun, Krueger, A. Chris, Donner, Pamela L, Hutchinson, Douglas K, Flentge, Charles, Betebenner, David, Rockway, Todd, Maring, Clarence J, Ng, Teresa I, Krishnan, Preethi, Pilot-Matias, Tami, Collins, Christine, Panchal, Neeta, Reisch, Thomas, Dekhtyar, Tatyana, Mondal, Rubina, Stolarik, DeAnne F, Gao, Yi, Gao, Wenqing, Beno, David A, Kati, Warren M

Volltext

Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design von Dietrich, Justin D, Longenecker, Kenton L, Wilson, Noel S, Goess, Christian, Panchal, Sanjay C, Swann, Steven L, Petros, Andrew M, Hobson, Adrian D, Ihle, David, Song, Danying, Richardson, Paul, Comess, Kenneth M, Cox, Philip B, Dombrowski, Amanda, Sarris, Kathy, Donnelly-Roberts, Diana L, Duignan, David B, Gomtsyan, Arthur, Jung, Paul, Krueger, A Chris, Mathieu, Suzanne, McClure, Andrea, Stoll, Vincent S, Wetter, Jill, Mankovich, John A, Hajduk, Philip J, Vasudevan, Anil, Stoffel, Robert H, Sun, Chaohong

Volltext

Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides von Chris Krueger, A., Madigan, Darold L., Jiang, Wen W., Kati, Warren M., Liu, Dachun, Liu, Yaya, Maring, Clarence J., Masse, Sherie, McDaniel, Keith F., Middleton, Tim, Mo, Hongmei, Molla, Akhteruzzaman, Montgomery, Debra, Pratt, John K., Rockway, Todd W., Zhang, Rong, Kempf, Dale J.

Volltext

Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailabili... von Randolph, John T, Krueger, A. Chris, Donner, Pamela L, Pratt, John K, Liu, Dachun, Motter, Christopher E, Rockway, Todd W, Tufano, Michael D, Wagner, Rolf, Lim, Hock B, Beyer, Jill M, Mondal, Rubina, Panchal, Neeta S, Colletti, Lynn, Liu, Yaya, Koev, Gennadiy, Kati, Warren M, Hernandez, Lisa E, Beno, David W. A, Longenecker, Kenton L, Stewart, Kent D, Dumas, Emily O, Molla, Akhteruzzaman, Maring, Clarence J

Volltext

Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: Synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif von Krueger, A. Chris, Randolph, John T., DeGoey, David A., Donner, Pamela L., Flentge, Charles A., Hutchinson, Douglas K., Liu, Dachun, Motter, Christopher E., Rockway, Todd W., Wagner, Rolf, Beno, David W.A., Koev, Gennadiy, Lim, Hock B., Beyer, Jill M., Mondal, Rubina, Liu, Yaya, Kati, Warren M., Longenecker, Kenton L., Molla, Akhteruzzaman, Stewart, Kent D., Maring, Clarence J.

Volltext

Synthesis of potent pyrrolidine influenza neuraminidase inhibitors von Krueger, A. Chris, Xu, Yibo, Kati, Warren M., Kempf, Dale J., Maring, Clarence J., McDaniel, Keith F., Molla, Akhteruzzaman, Montgomery, Debra, Kohlbrenner, William E.

Volltext

Inhibitors of Hepatitis C Virus Polymerase: Synthesis and Biological Characterization of Unsymmetrical Dialkyl-Hydroxynaphthalenoyl-benzothiadiazines von Wagner, Rolf, Larson, Daniel P, Beno, David W. A, Bosse, Todd D, Darbyshire, John F, Gao, Yi, Gates, Bradley D, He, Wenping, Henry, Rodger F, Hernandez, Lisa E, Hutchinson, Douglas K, Jiang, Wen W, Kati, Warren M, Klein, Larry L, Koev, Gennadiy, Kohlbrenner, William, Krueger, A. Chris, Liu, Jinrong, Liu, Yaya, Long, Michelle A, Maring, Clarence J, Masse, Sherie V, Middleton, Tim, Montgomery, Debra A, Pratt, John K, Stuart, Patricia, Molla, Akhteruzzaman, Kempf, Dale J

Volltext

Inhibitors of HCV NS5B polymerase: Synthesis and structure–activity relationships of unsymmetrical 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives von Krueger, A. Chris, Madigan, Darold L., Green, Brian E., Hutchinson, Douglas K., Jiang, Wen W., Kati, Warren M., Liu, Yaya, Maring, Clarence J., Masse, Sherie V., McDaniel, Keith F., Middleton, Tim R., Mo, Hongmei, Molla, Akhteruzzaman, Montgomery, Debra A., Ng, Teresa I., Kempf, Dale J.

Volltext

On the Question of Asymmetric Induction with Acyclic Allylic Substrates. An Asymmetric Synthesis of (+)-Polyoxamic Acid von Trost, Barry M, Krueger, A. Chris, Bunt, Richard C, Zambrano, Jorge

Volltext

1,3-Dipolar cycloaddition reactions of ester-stabilized azomethine ylides with acrolein: a one-pot regio- and stereoselective synthesis of N-substituted 4-formyl-5-vinyl proline ca... von Gu, Yu Gui, Xu, Yibo, Krueger, A.Chris, Madigan, Darold, Sham, Hing L.

Volltext

Metal promoted higher-order cycloaddition reactions. A facile entry into substituted eight- and ten-membered carbocycles von Rigby, James H., Ateeq, Humy S., Krueger, A. Chris

Volltext

Metal-promoted higher-order cycloaddition reactions. Stereochemical, regiochemical, and mechanistic aspects of the [6.pi. + 4.pi.] reaction von Rigby, James H, Ateeq, Humy S, Charles, Nelly R, Cuisiat, Stephane V, Ferguson, Mark D, Henshilwood, James A, Krueger, A. Chris, Ogbu, Cyprian O, Short, Kevin M, Heeg, M. J

Volltext

ChemInform Abstract: Novel Hepatitis C Virus Replicon Inhibitors: Synthesis and Structure-Activity Relationships of Fused Pyrimidine Derivatives von Krueger, A. Chris, ., et al

Volltext

Studies on the Metalation and Alkylation of Dihydrothiepin-1,1-dioxide. Applications to Synthesis von Rigby, James H., Krueger, A. Chris

Volltext

Systems and methods for just-in-time construction training and real time productivity statistical analysis von KRUEGER CHRIS A

Volltext bestellen

Inhibitors of HCV NS5B Polymerase: Synthesis and Structure-Activity Relationships of N-Alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine Sulfamides von Krueger, A. Chris, ., et al

Volltext