Triggering T-cell activity in CLL von Mertens, Daniel, Krönke, Jan

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Anti-B-Cell Maturation Antigen BiTE Molecule AMG 420 Induces Responses in Multiple Myeloma von Topp, Max S., Duell, Johannes, Zugmaier, Gerhard, Attal, Michel, Moreau, Philippe, Langer, Christian, Kroenke, Jan, Facon, Thierry, Salnikov, Alexey V., Lesley, Robin, Beutner, Karl, Kalabus, James, Rasmussen, Erik, Riemann, Kathrin, Minella, Alex C., Munzert, Gerd, Einsele, Hermann

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Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells von Krönke, Jan, Udeshi, Namrata D., Narla, Anupama, Grauman, Peter, Hurst, Slater N., McConkey, Marie, Svinkina, Tanya, Heckl, Dirk, Comer, Eamon, Li, Xiaoyu, Ciarlo, Christie, Hartman, Emily, Munshi, Nikhil, Schenone, Monica, Schreiber, Stuart L., Carr, Steven A., Ebert, Benjamin L

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Inhibition of Casein Kinase 1 Alpha in Acute Myeloid Leukemia von Ebert, Benjamin L, Krönke, Jan

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Ubiquitination and Ubiquitin-Like Modifications in Multiple Myeloma: Biology and Therapy von Wirth, Matthias, Schick, Markus, Keller, Ulrich, Kroenke, Jan

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The molecular mechanism of thalidomide analogs in hematologic malignancies von Lindner, Stefanie, Krönke, Jan

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Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders von Steinebach, Christian, Ng, Yuen Lam Dora, Sosi, Izidor, Lee, Chih-Shia, Chen, Sirui, Lindner, Stefanie, Vu, Lan Phuong, Bricelj, Aleša, Haschemi, Reza, Monschke, Marius, Steinwarz, Elisabeth, Wagner, Karl G, Bendas, Gerd, Luo, Ji, Gütschow, Michael, Krönke, Jan

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Targeting the deubiquitinase USP7 for degradation with PROTACs von Murgai, Arunima, Sosi, Izidor, Gobec, Martina, Lemnitzer, Patricia, Proj, Matic, Wittenburg, Sophie, Voget, Rabea, Gütschow, Michael, Krönke, Jan, Steinebach, Christian

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Comparison Between 5-Azacytidine Treatment and Allogeneic Stem-Cell Transplantation in Elderly Patients With Advanced MDS According to Donor Availability (VidazaAllo Study) von Kroeger, Nicolaus, Sockel, Katja, Wolschke, Christine, Bethge, Wolfgang, Schlenk, Richard F., Wolf, Dominik, Stadler, Michael, Kobbe, Guido, Wulf, Gerald, Bug, Gesine, Schaefer-Eckart, Kerstin, Scheid, Christof, Nolte, Florian, Kroenke, Jan, Stelljes, Matthias, Beelen, Dietrich, Heinzelmann, Marion, Haase, Detlef, Buchner, Hannes, Bleckert, Gabriele, Giagounidis, Aristoteles, Platzbecker, Uwe

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PROTAC-mediated crosstalk between E3 ligases von Steinebach, Christian, Kehm, Hannes, Lindner, Stefanie, Vu, Lan Phuong, Köpff, Simon, López Mármol, Álvaro, Weiler, Corinna, Wagner, Karl G, Reichenzeller, Michaela, Krönke, Jan, Gütschow, Michael

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Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery von Wang, Zefeng, Shaabani, Shabnam, Gao, Xiang, Ng, Yuen Lam Dora, Sapozhnikova, Valeriia, Mertins, Philipp, Krönke, Jan, Dömling, Alexander

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Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial von Kapp-Schwoerer, Silke, Weber, Daniela, Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Krönke, Jan, Theis, Frauke, Rücker, Frank G., Teleanu, Maria-Veronica, Panina, Ekaterina, Jahn, Nikolaus, Herzig, Julia, Kubanek, Lena, Schrade, Anika, Göhring, Gudrun, Fiedler, Walter, Kindler, Thomas, Schroeder, Thomas, Mayer, Karin T., Lübbert, Michael, Wattad, Mohammed, Götze, Katharina S., Horst, Heinz A., Koller, Elisabeth, Wulf, Gerald, Schleicher, Jan, Bentz, Martin, Krauter, Jürgen, Bullinger, Lars, Krzykalla, Julia, Benner, Axel, Schlenk, Richard F., Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze

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Comparison Between 5-Azacytidine Treatment and Allogeneic Stem-Cell Transplantation in Elderly Patients With Advanced MDS According to Donor Availability (VidazaAllo Study) von Kröger, Nicolaus, Sockel, Katja, Wolschke, Christine, Bethge, Wolfgang, Schlenk, Richard F, Wolf, Dominik, Stadler, Michael, Kobbe, Guido, Wulf, Gerald, Bug, Gesine, Schäfer-Eckart, Kerstin, Scheid, Christof, Nolte, Florian, Krönke, Jan, Stelljes, Matthias, Beelen, Dietrich, Heinzelmann, Marion, Haase, Detlef, Buchner, Hannes, Bleckert, Gabriele, Giagounidis, Aristoteles, Platzbecker, Uwe

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Homo-PROTACs for the Chemical Knockdown of Cereblon von Steinebach, Christian, Lindner, Stefanie, Udeshi, Namrata D, Mani, Deepak C, Kehm, Hannes, Köpff, Simon, Carr, Steven A, Gütschow, Michael, Krönke, Jan

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IDH1 and IDH2 Mutations Are Frequent Genetic Alterations in Acute Myeloid Leukemia and Confer Adverse Prognosis in Cytogenetically Normal Acute Myeloid Leukemia With NPM1 Mutation... von PASCHKA, Peter, SCHLENK, Richard F, HORST, Heinz-A, GERMING, Ulrich, DÖHNER, Hartmut, DÖHNER, Konstanze, GAIDZIK, Verena I, HABDANK, Marianne, KRÖNKE, Jan, BULLINGER, Lars, SPÄTH, Daniela, KAYSER, Sabine, ZUCKNICK, Manuela, GÖTZE, Katharina

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In vitro testing of drug response in primary multiple myeloma cells using a microwell-based technology von Krüger, Josefine, Blau, Igor Wolfgang, Blau, Olga, Bettelli, Alice, Rocchi, Laura, Bocchi, Massimo, Krönke, Jan, Bullinger, Lars, Keller, Ulrich, Nogai, Axel

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Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation von Cocciardi, Sibylle, Dolnik, Anna, Kapp-Schwoerer, Silke, Rücker, Frank G., Lux, Susanne, Blätte, Tamara J., Skambraks, Sabrina, Krönke, Jan, Heidel, Florian H., Schnöder, Tina M., Corbacioglu, Andrea, Gaidzik, Verena I., Paschka, Peter, Teleanu, Veronica, Göhring, Gudrun, Thol, Felicitas, Heuser, Michael, Ganser, Arnold, Weber, Daniela, Sträng, Eric, Kestler, Hans A., Döhner, Hartmut, Bullinger, Lars, Döhner, Konstanze

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Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma von Ng, Yuen Lam Dora, Ramberger, Evelyn, Bohl, Stephan R., Dolnik, Anna, Steinebach, Christian, Conrad, Theresia, Müller, Sina, Popp, Oliver, Kull, Miriam, Haji, Mohamed, Gütschow, Michael, Döhner, Hartmut, Walther, Wolfgang, Keller, Ulrich, Bullinger, Lars, Mertins, Philipp, Krönke, Jan

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Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia von Krönke, Jan, Bullinger, Lars, Teleanu, Veronica, Tschürtz, Florian, Gaidzik, Verena I., Kühn, Michael W.M., Rücker, Frank G., Holzmann, Karlheinz, Paschka, Peter, Kapp-Schwörer, Silke, Späth, Daniela, Kindler, Thomas, Schittenhelm, Marcus, Krauter, Jürgen, Ganser, Arnold, Göhring, Gudrun, Schlegelberger, Brigitte, Schlenk, Richard F., Döhner, Hartmut, Döhner, Konstanze

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Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs von Steinebach, Christian, Bricelj, Aleša, Murgai, Arunima, Sosič, Izidor, Bischof, Luca, Ng, Yuen Lam Dora, Heim, Christopher, Maiwald, Samuel, Proj, Matic, Voget, Rabea, Feller, Felix, Košmrlj, Janez, Sapozhnikova, Valeriia, Schmidt, Annika, Zuleeg, Maximilian Rudolf, Lemnitzer, Patricia, Mertins, Philipp, Hansen, Finn K., Gütschow, Michael, Krönke, Jan, Hartmann, Marcus D.

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