Final Report of Phase 1 Study of the DOT1L Inhibitor, Pinometostat (EPZ-5676), in Children with Relapsed or Refractory MLL-r Acute Leukemia von Shukla, Neerav, Wetmore, Cynthia, O'Brien, Maureen M, Silverman, Lewis B., Brown, Patrick, Cooper, Todd M, Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott, Suttle, Ben, Waters, Nigel J., Krivstov, Andrei V, Armstrong, Scott A., Ho, Peter T, Gore, Lia

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Preliminary Report of the Phase 1 Study of the DOT1L Inhibitor, Pinometostat, EPZ-5676, in Children with Relapsed or Refractory MLL-r Acute Leukemia: Safety, Exposure and Target In... von Shukla, Neerav, O'Brien, Maureen M., Silverman, Lewis B., Pauly, Melinda, Wetmore, Cynthia, Loh, Mignon L., Whitlock, James A., Brown, Patrick, Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott, Pimentel, Patricia, Waters, Nigel J., Krivstov, Andrei V, Koche, Richard, Armstrong, Scott A., Ho, Peter T, Gore, Lia

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A Phase 1 Study of the DOT1L Inhibitor, Pinometostat (EPZ-5676), in Adults with Relapsed or Refractory Leukemia: Safety, Clinical Activity, Exposure and Target Inhibition von Stein, Eytan M., Garcia-Manero, Guillermo, Rizzieri, David A., Tibes, Raoul, Berdeja, Jesus G., Jongen-Lavrencic, Mojca, Altman, Jessica K., Dohner, Hartmut, Thomson, Blythe, Blakemore, Stephen J., Daigle, Scott, Fine, Greg, Waters, Nigel J., Krivstov, Andrei V, Koche, Richard, Armstrong, Scott A., Ho, Peter T, Lowenberg, Bob, Tallman, Martin S

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The Myocyte Enhancer Factor 2C (MEF2C) Is a Direct Transcriptional Target of HOXA9 and Mediates Leukemia Survival in Human Mixed-Lineage Leukemias von Faber, Jorg, Krivstov, Andrei V., Stubbs, Matthew C., van den Heuvel-Eibrink, Marry, Kung, Andrew L., Zwaan, Christian M., Armstrong, Scott A.

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MLL-Fusion Proteins Induce a Stem Cell Program in Committed Progenitors To Generate Leukemia Stem Cells von Krivstov, Andrei V., Twomey, David, Feng, Zhaohui, Stubbs, Matthew C., Golub, Todd R., Armstrong, Scott A.

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