Clinical Study of Single‐Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B von Gane, Edward, Yuen, Man‐Fung, Kim, Dong Joon, Chan, Henry Lik‐Yuen, Surujbally, Bernadette, Pavlovic, Vedran, Das, Sudip, Triyatni, Miriam, Kazma, Remi, Grippo, Joseph F., Buatois, Simon, Lemenuel‐Diot, Annabelle, Krippendorff, Ben‐Fillippo, Mueller, Henrik, Zhang, Yuchen, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young‐Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung‐Hui, Wat, Cynthia

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Influence of Molecular size on the clearance of antibody fragments von Li, Zhe, Krippendorff, Ben-Fillippo, Shah, Dhaval K.

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Interstitial IgG antibody pharmacokinetics assessed by combined in vivo‐ and physiologically‐based pharmacokinetic modelling approaches von Eigenmann, Miro J., Karlsen, Tine V., Krippendorff, Ben‐Fillippo, Tenstad, Olav, Fronton, Ludivine, Otteneder, Michael B., Wiig, Helge

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Influence of molecular size on tissue distribution of antibody fragments von Li, Zhe, Krippendorff, Ben-Fillippo, Sharma, Sharad, Walz, Antje C, Lavé, Thierry, Shah, Dhaval K

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Capacity limits of asialoglycoprotein receptor-mediated liver targeting von Bon, Charlotte, Hofer, Thomas, Bousquet-Mélou, Alain, Davies, Mark R, Krippendorff, Ben-Fillippo

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Quantification of IgG monoclonal antibody clearance in tissues von Eigenmann, Miro J, Fronton, Ludivine, Grimm, Hans Peter, Otteneder, Michael B, Krippendorff, Ben-Fillippo

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G‑Quadruplex DNA as a Molecular Target for Induced Synthetic Lethality in Cancer Cells von McLuckie, Keith I. E, Di Antonio, Marco, Zecchini, Heather, Xian, Jian, Caldas, Carlos, Krippendorff, Ben-Fillippo, Tannahill, David, Lowe, Christopher, Balasubramanian, Shankar

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Translating pharmacology models effectively to predict therapeutic benefit von Dudal, Sherri, Bissantz, Caterina, Caruso, Antonello, David-Pierson, Pascale, Driessen, Wouter, Koller, Erich, Krippendorff, Ben-Fillippo, Lechmann, Martin, Olivares-Morales, Andrés, Paehler, Axel, Rynn, Caroline, Türck, Dietrich, Van De Vyver, Arthur, Wang, Ken, Winther, Lotte

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Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties von Sela, Tatjana, Mansø, Mads, Siegel, Michel, Marban-Doran, Céline, Ducret, Axel, Niewöhner, Jens, Ravn, Jacob, Martin, Rainer E., Sommer, Annika, Lohmann, Sabine, Krippendorff, Ben-Fillippo, Ladefoged, Mette, Indlekofer, Annette, Quaiser, Tom, Bueddefeld, Florian, Koller, Erich, Mohamed, Mohamed Y., Oelschlaegel, Tobias, Gothelf, Kurt V., Hofer, Kerstin, Schumacher, Felix F.

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A re-engineered immunotoxin shows promising preclinical activity in ovarian cancer von Kollmorgen, Gwendlyn, Palme, Klara, Seidl, Annette, Scheiblich, Stefan, Birzele, Fabian, Wilson, Sabine, Clemens, Christian, Voss, Edgar, Kaufmann, Martin, Hirzel, Klaus, Rieder, Natascha, Krippendorff, Ben-Fillippo, Herting, Frank, Niederfellner, Gerhard

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Characterization of a re-engineered, mesothelin-targeted Pseudomonas exotoxin fusion protein for lung cancer therapy von Bauss, Frieder, Lechmann, Martin, Krippendorff, Ben-Fillippo, Staack, Roland, Herting, Frank, Festag, Matthias, Imhof-Jung, Sabine, Hesse, Friederike, Pompiati, Marc, Kollmorgen, Gwendlyn, da Silva Mateus Seidl, Rita, Bossenmaier, Birgit, Lau, Wilma, Schantz, Christian, Stracke, Jan O., Brinkmann, Ulrich, Onda, Masanori, Pastan, Ira, Bosslet, Klaus, Niederfellner, Gerhard

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Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer von Courtin, Aurélie, Richards, Frances M, Bapiro, Tashinga E, Bramhall, Jo L, Neesse, Albrecht, Cook, Natalie, Krippendorff, Ben-Fillippo, Tuveson, David A, Jodrell, Duncan I

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Nonlinear pharmacokinetics of therapeutic proteins resulting from receptor mediated endocytosis von Krippendorff, Ben-Fillippo, Kuester, Katharina, Kloft, Charlotte, Huisinga, Wilhelm

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Abstract 4510: RG7787 - a novel de-immunized PE based fusion protein for therapy of mesothelin-positive solid tumors von Niederfellner, Gerhard, Bauss, Frieder, Imhof-Jung, Sabine, Hesse, Friederike, Kronenberg, Sven, Staak, Roland, Lechmann, Martin, Krippendorff, Ben, Richter, Wolfgang, Mateus, Rita, Kollmorgen, Gwendlyn, Brinkmann, Ulli, Onda, Masanori, Pastan, Ira, Bosslet, Klaus

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Optimizing Classification of Drug-Drug Interaction Potential for CYP450 Isoenzyme Inhibition Assays in Early Drug Discovery von Krippendorff, Ben-Fillippo, Lienau, Philip, Reichel, Andreas, Huisinga, Wilhelm

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Predicting the F(ab)-mediated effect of monoclonal antibodies in vivo by combining cell-level kinetic and pharmacokinetic modelling von Krippendorff, Ben-Fillippo, Oyarzún, Diego A., Huisinga, Wilhelm

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The EGFR demonstrates linear signal transmission von Oyarzún, Diego A, Bramhall, Jo L, López-Caamal, Fernando, Richards, Frances M, Jodrell, Duncan I, Krippendorff, Ben-Fillippo

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Reply von Wat, Cynthia, Gane, Edward, Yuen, Man‐Fung, Pavlovic, Vedran, Mueller, Henrik, Krippendorff, Ben‐Fillippo, Grippo, Joseph F., Ottosen, Soren

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Reply von Wat, Cynthia, Gane, Edward, Yuen, Man‐Fung, Pavlovic, Vedran, Mueller, Henrik, Krippendorff, Ben‐Fillippo, Grippo, Joseph F., Ottosen, Soren

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Reply von Wat, Cynthia, Gane, Edward, Yuen, Man-Fung, Pavlovic, Vedran, Mueller, Henrik, Krippendorff, Ben-Fillippo, Grippo, Joseph F, Ottosen, Soren

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