Structural basis for isoform-specific inhibition of human CTPS1 von Lynch, Eric M., DiMattia, Michael A., Albanese, Steven, van Zundert, Gydo C. P., Hansen, Jesse M., Quispe, Joel D., Kennedy, Madison A., Verras, Andreas, Borrelli, Kenneth, Toms, Angela V., Kaila, Neelu, Kreutter, Kevin D., McElwee, Joshua J., Kollman, Justin M.

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Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase von Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin

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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease von Leonard, Kristi A, Madge, Lisa A, Krawczuk, Paul J, Wang, Aihua, Kreutter, Kevin D, Bacani, Genesis M, Chai, Wenying, Smith, Russell C, Tichenor, Mark S, Harris, Michael C, Malaviya, Ravi, Seierstad, Mark, Johnson, Marguerite E, Venable, Jennifer D, Kim, Suzie, Hirst, Gavin C, Mathur, Ashok S, Rao, Tadimeti S, Edwards, James P, Rizzolio, Michele C, Koudriakova, Tatiana

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Spontaneous Diabetes Mellitus in Transgenic Mice Expressing Human Islet Amyloid Polypeptide von Janson, Juliette, Soeller, Walter C., Roche, Patrick C., Nelson, Robin T., Torchia, Anthony J., Kreutter, David K., Butler, Peter C.

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Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt von Kummer, David A., Cummings, Maxwell D., Abad, Marta, Barbay, Joseph, Castro, Glenda, Wolin, Ronald, Kreutter, Kevin D., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi

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6-Substituted quinolines as RORγt inverse agonists von Barbay, J. Kent, Cummings, Maxwell D., Abad, Marta, Castro, Glenda, Kreutter, Kevin D., Kummer, David A., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Tanis, Virginia M., Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Wolin, Ronald, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi

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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity von Tichenor, Mark S, Wiener, John J. M, Rao, Navin L, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D, Bacani, Genesis M, Wei, Jianmei, Chang, Leon, Murrey, Heather E, Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J, Wu, JieJun, Seierstad, Mark, Bembenek, Scott D, Leonard, Kristi A, Lebsack, Alec D, Venable, Jennifer D, Edwards, James P

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Human islet amyloid polypeptide expression in COS-1 cells. A model of intracellular amyloidogenesis von O'Brien, TD, Butler, PC, Kreutter, DK, Kane, LA, Eberhardt, NL

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2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors von Lee, Lily, Kreutter, Kevin D., Pan, Wenxi, Crysler, Carl, Spurlino, John, Player, Mark R., Tomczuk, Bruce, Lu, Tianbao

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Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif von Kreutter, Kevin D., Lu, Tianbao, Lee, Lily, Giardino, Edward C., Patel, Sharmila, Huang, Hui, Xu, Guozhang, Fitzgerald, Mark, Haertlein, Barbara J., Mohan, Venkatraman, Crysler, Carl, Eisennagel, Stephen, Dasgupta, Malini, McMillan, Martin, Spurlino, John C., Huebert, Norman D., Maryanoff, Bruce E., Tomczuk, Bruce E., Damiano, Bruce P., Player, Mark R.

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The temporal integration of the aldosterone secretory response to angiotensin occurs via two intracellular pathways von Kojima, I, Kojima, K, Kreutter, D, Rasmussen, H

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Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells von Kreutter, D, Caldwell, A B, Morin, M J

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Regulation of protein kinase C activity by gangliosides von Kreutter, D, Kim, J Y, Goldenring, J R, Rasmussen, H, Ukomadu, C, DeLorenzo, R J, Yu, R K

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Amylin and CGRP induce insulin resistance via a receptor distinct from cAMP-coupled CGRP receptor von Kreutter, D. K, Orena, S. J, Torchia, A. J, Contillo, L. G, Andrews, G. C, Stevenson, R. W

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Amylin-induced in vivo insulin resistance in conscious rats : the liver is more sensitive to amylin than peripheral tissues von KOOPMANS, S. J, VAN MANSFELD, A. D. M, JANSZ, H. S, KRANS, H. M. J, RADDER, J. K, FROLICH, M, DE BOER, S. F, KREUTTER, D. K, ANDREWS, G. C, MAASSEN, J. A

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Antidiabetic agent englitazone enhances insulin action in nondiabetic rats without producing hypoglycemia von Stevenson, R.W., McPherson, R.K., Genereux, P.E., Danbury, B.H., Kreutter, D.K.

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Relationship of age and calcitonin gene-related peptide to postprandial hypotension von Edwards, B.J., Perry, H.M., Kaiser, F.E., Morley, J.E., Kraenzle, D., Stevenson, R., Kreutter, D.

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Kinetics and thermochemistry of ClCO formation from the Cl + CO association reaction von Nicovich, J. M., Kreutter, K. D., Wine, P. H.

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Age-related changes in amylin secretion von Edwards, Beatriz J., Perry, Horace M., Kaiser, Fran E., Morley, John E., Kraenzle, Dale, Kreutter, David K., Stevenson, Ralph W.

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Stereochemical Dependence of Base-Catalyzed Cleavage of Cyclic Peroxy Ketals von Snider, Barry B, Shi, Zhongping, O'Neil, Steven V, Kreutter, Kevin D, Arakaki, Tracy L

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