Design, Synthesis, and Structure–Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5‑Lipoxygenase von Hiesinger, Kerstin, Kramer, Jan S, Beyer, Sandra, Eckes, Timon, Brunst, Steffen, Flauaus, Cathrin, Wittmann, Sandra K, Weizel, Lilia, Kaiser, Astrid, Kretschmer, Simon B. M, George, Sven, Angioni, Carlo, Heering, Jan, Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Schmidtko, Achim, Pogoryelov, Denys, Pfeilschifter, Josef, Hofmann, Bettina, Steinhilber, Dieter, Schwalm, Stephanie, Proschak, Ewgenij

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Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism von Rödl, Carmen B., Vogt, Dominik, Kretschmer, Simon B.M., Ihlefeld, Katja, Barzen, Sebastian, Brüggerhoff, Astrid, Achenbach, Janosch, Proschak, Ewgenij, Steinhilber, Dieter, Stark, Holger, Hofmann, Bettina

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Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418 von Maucher, Isabelle V., Rühl, Michael, Kretschmer, Simon B.M., Hofmann, Bettina, Kühn, Benjamin, Fettel, Jasmin, Vogel, Anja, Flügel, Karsten T., Manolikakes, Georg, Hellmuth, Nadine, Häfner, Ann-Kathrin, Golghalyani, Vahid, Ball, Ann-Katrin, Piesche, Matthias, Matrone, Carmela, Geisslinger, Gerd, Parnham, Michael J., Karas, Michael, Steinhilber, Dieter, Roos, Jessica, Maier, Thorsten J.

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Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles von Kretschmer, Simon B.M., Woltersdorf, Stefano, Vogt, Dominik, Lillich, Felix F., Rühl, Michael, Karas, Michael, Maucher, Isabelle V., Roos, Jessica, Häfner, Ann-Kathrin, Kaiser, Astrid, Wurglics, Mario, Schubert-Zsilavecz, Manfred, Angioni, Carlo, Geisslinger, Gerd, Stark, Holger, Steinhilber, Dieter, Hofmann, Bettina

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