Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors von Krentz, Nicole A.J., Lee, Michelle Y.Y., Xu, Eric E., Sproul, Shannon L.J., Maslova, Alexandra, Sasaki, Shugo, Lynn, Francis C.

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TrxG Complex Catalytic and Non-catalytic Activity Play Distinct Roles in Pancreas Progenitor Specification and Differentiation von Campbell, Stephanie A., McDonald, Cassandra L., Krentz, Nicole A.J., Lynn, Francis C., Hoffman, Brad G.

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Npas4 Is a Novel Activity-Regulated Cytoprotective Factor in Pancreatic β-Cells von SABATINI, Paul V, KRENTZ, Nicole A. J, ZARROUKI, Bader, WESTWELL-ROPER, Clara Y, CUILAN NIAN, UY, Ryan A, SHAPIRO, A. M. James, POITOUT, Vincent, LYNN, Francis C

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Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding von Alghamdi, Tamadher A., Krentz, Nicole A.J., Smith, Nancy, Spigelman, Aliya F., Rajesh, Varsha, Jha, Alokkumar, Ferdaoussi, Mourad, Suzuki, Kunimasa, Yang, Jing, Manning Fox, Jocelyn E., Sun, Han, Sun, Zijie, Gloyn, Anna L., MacDonald, Patrick E.

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Insights into pancreatic islet cell dysfunction from type 2 diabetes mellitus genetics von Krentz, Nicole A. J., Gloyn, Anna L.

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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion von Dwivedi, Om Prakash, Lehtovirta, Mikko, Hastoy, Benoit, Chandra, Vikash, Krentz, Nicole A. J., Kleiner, Sandra, Jain, Deepak, Richard, Ann-Marie, Abaitua, Fernando, Beer, Nicola L., Grotz, Antje, Prasad, Rashmi B., Hansson, Ola, Ahlqvist, Emma, Krus, Ulrika, Artner, Isabella, Suoranta, Anu, Gomez, Daniel, Baras, Aris, Champon, Benoite, Payne, Anthony J., Moralli, Daniela, Thomsen, Soren K., Kramer, Philipp, Spiliotis, Ioannis, Ramracheya, Reshma, Chabosseau, Pauline, Theodoulou, Andria, Cheung, Rebecca, van de Bunt, Martijn, Flannick, Jason, Trombetta, Maddalena, Bonora, Enzo, Wolheim, Claes B., Sarelin, Leena, Bonadonna, Riccardo C., Rorsman, Patrik, Davies, Benjamin, Brosnan, Julia, McCarthy, Mark I., Otonkoski, Timo, Lagerstedt, Jens O., Rutter, Guy A., Gromada, Jesper, Gloyn, Anna L., Tuomi, Tiinamaija, Groop, Leif

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Improvements in stem cell to beta-cell differentiation for the treatment of diabetes von Krentz, Nicole A.J.

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Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors von Krentz, Nicole A.J., van Hoof, Dennis, Li, Zhongmei, Watanabe, Akie, Tang, Mei, Nian, Cuilan, German, Michael S., Lynn, Francis C.

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PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development von Lau, Hwee Hui, Krentz, Nicole A. J., Abaitua, Fernando, Perez-Alcantara, Marta, Chan, Jun-Wei, Ajeian, Jila, Ghosh, Soumita, Lee, Yunkyeong, Yang, Jing, Thaman, Swaraj, Champon, Benoite, Sun, Han, Jha, Alokkumar, Hoon, Shawn, Tan, Nguan Soon, Gardner, Daphne Su-Lyn, Kao, Shih Ling, Tai, E. Shyong, Gloyn, Anna L., Teo, Adrian Kee Keong

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Electrophysiological Characterization of Inducible Pluripotent Stem Cell-Derived Human β-Like Cells and an SLC30A8 Disease Model von Jaffredo, Manon, Krentz, Nicole A J, Champon, Benoite, Duff, Claire E, Nawaz, Sameena, Beer, Nicola, Honore, Christian, Clark, Anne, Rorsman, Patrik, Lang, Jochen, Gloyn, Anna L, Raoux, Matthieu, Hastoy, Benoit

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Dynamic Ins2 Gene Activity Defines β-Cell Maturity States von Chu, Chieh Min Jamie, Modi, Honey, Ellis, Cara, Krentz, Nicole A J, Skovsø, Søs, Zhao, Yiwei Bernie, Cen, Haoning, Noursadeghi, Nilou, Panzhinskiy, Evgeniy, Hu, Xiaoke, Dionne, Derek A, Xia, Yi Han, Xuan, Shouhong, Huising, Mark O, Kieffer, Timothy J, Lynn, Francis C, Johnson, James D

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Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression von Mattis, Katia K., Krentz, Nicole A. J., Metzendorf, Christoph, Abaitua, Fernando, Spigelman, Aliya F., Sun, Han, Ikle, Jennifer M., Thaman, Swaraj, Rottner, Antje K., Bautista, Austin, Mazzaferro, Eugenia, Perez-Alcantara, Marta, Manning Fox, Jocelyn E., Torres, Jason M., Wesolowska-Andersen, Agata, Yu, Grace Z., Mahajan, Anubha, Larsson, Anders, MacDonald, Patrick E., Davies, Benjamin, den Hoed, Marcel, Gloyn, Anna L.

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TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm von Krentz, Nicole A J, Nian, Cuilan, Lynn, Francis C

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Restoring normal islet mass and function in type 1 diabetes through regenerative medicine and tissue engineering von Krentz, Nicole A J, Shea, Lonnie D, Huising, Mark O, Shaw, James A M

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SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models von Xu, Eric E., Krentz, Nicole A. J., Tan, Sara, Chow, Sam Z., Tang, Mei, Nian, Cuilan, Lynn, Francis C.

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2050-P: A Multiomics Investigation of a Patient-Derived HNF-1A MODY IPSC Disease Model Reveals Insights into Its Role in Pancreatic Islet Development and Function von DUFF, CLAIRE, JENSEN, RIKKE REJNHOLDT, PEREZ-ALCANTARA, MARTA, RASMUSSEN, MIKKEL, GROTZ, ANTJE, JANSEN, MAX, HOLST, BJØRN, CLAUSEN, CHRISTIAN, KRENTZ, NICOLE A.J., HANSSON, MATTIAS, MCCARTHY, MARK I., GLOYN, ANNA L., WESOLOWSKA-ANDERSEN, AGATA, HONORE, CHRISTIAN

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A regulatory network controls nephrocan expression and midgut patterning von Hou, Juan, Wei, Wei, Saund, Ranajeet S, Xiang, Ping, Cunningham, Thomas J, Yi, Yuyin, Alder, Olivia, Lu, Daphne Y D, Savory, Joanne G A, Krentz, Nicole A J, Montpetit, Rachel, Cullum, Rebecca, Hofs, Nicole, Lohnes, David, Humphries, R Keith, Yamanaka, Yojiro, Duester, Gregg, Saijoh, Yukio, Hoodless, Pamela A

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77 - Ins2 Gene Bursting Activity Defines a Mature β-Cell State von Modi, Honey, Chu, Jamie, Skovsø, Søs, Ellis, Cara, Krentz, Nicole A.J., Zhao, Yiwei, Cen, Haoning Howard, Noursadeghi, Nilou, Panzhinskiy, Evgeniy, Hu, Xioake, Dionne, Derek A., Xuan, Shouhong, Kieffer, Timothy J., Lynn, Francis C., Johnson, James

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Npas4 is a novel activity--regulated cytoprotective factor in pancreatic [beta]-cells von Sabatini, Paul V, Krentz, Nicole A.J, Zarrouki, Bader, Westwell-Roper, Clara Y, Nian, Cuilan, Uy, Ryan A, Shapiro, A.M. James, Poitout, Vincent, Lynn, Francis C

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