Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1) von Kanouni, Toufike, Severin, Christophe, Cho, Robert W, Yuen, Natalie Y.-Y, Xu, Jiangchun, Shi, Lihong, Lai, Chon, Del Rosario, Joselyn R, Stansfield, Ryan K, Lawton, Lee N, Hosfield, David, O’Connell, Shawn, Kreilein, Matt M, Tavares-Greco, Paula, Nie, Zhe, Kaldor, Stephen W, Veal, James M, Stafford, Jeffrey A, Chen, Young K

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Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo von Saenz, Steven A, Local, Andrea, Carr, Tiffany, Shakya, Arvind, Koul, Shivsmriti, Hu, Haiqing, Chourb, Lisa, Stedman, Justin, Malley, Jenna, D'Agostino, Laura Akullian, Shanmugasundaram, Veerabahu, Malona, John, Schwartz, C Eric, Beebe, Lisa, Clements, Meghan, Rajaraman, Ganesh, Cho, John, Jiang, Lan, Dubrovskiy, Alex, Kreilein, Matt, Shimanovich, Roman, Hamann, Lawrence G, Escoubet, Laure, Ellis, J Michael

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Small molecule allosteric inhibitors of ROR[gamma]t block Th17-dependent inflammation and associated gene expression in vivo von Saenz, Steven A, Local, Andrea, Carr, Tiffany, Shakya, Arvind, Koul, Shivsmriti, Hu, Haiqing, Chourb, Lisa, Stedman, Justin, Malley, Jenna, D'Agostino, Laura Akullian, Shanmugasundaram, Veerabahu, Malona, John, Schwartz, C. Eric, Beebe, Lisa, Clements, Meghan, Rajaraman, Ganesh, Cho, John, Jiang, Lan, Dubrovskiy, Alex, Kreilein, Matt, Shimanovich, Roman, Hamann, Lawrence G, Escoubet, Laure, Ellis, J. Michael

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Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo von Steven A. Saenz, Andrea Local, Tiffany Carr, Arvind Shakya, Shivsmriti Koul, Haiqing Hu, Lisa Chourb, Justin Stedman, Jenna Malley, Laura Akullian D’Agostino, Veerabahu Shanmugasundaram, John Malona, C. Eric Schwartz, Lisa Beebe, Meghan Clements, Ganesh Rajaraman, John Cho, Lan Jiang, Alex Dubrovskiy, Matt Kreilein, Roman Shimanovich, Lawrence G. Hamann, Laure Escoubet, J. Michael Ellis

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