cGAS phase separation inhibits TREX1-mediated DNA degradation and enhances cytosolic DNA sensing von Zhou, Wen, Mohr, Lisa, Maciejowski, John, Kranzusch, Philip J

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Bacterial gasdermins reveal an ancient mechanism of cell death von Johnson, Alex G, Wein, Tanita, Mayer, Megan L, Duncan-Lowey, Brianna, Yirmiya, Erez, Oppenheimer-Shaanan, Yaara, Amitai, Gil, Sorek, Rotem, Kranzusch, Philip J

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Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA von Barnett, Katherine C., Coronas-Serna, Julia M., Zhou, Wen, Ernandes, Michael J., Cao, Anh, Kranzusch, Philip J., Kagan, Jonathan C.

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Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2′,3′ cGAMP Signaling von Kranzusch, Philip J., Wilson, Stephen C., Lee, Amy S.Y., Berger, James M., Doudna, Jennifer A., Vance, Russell E.

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Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity von Kranzusch, Philip J., Lee, Amy Si-Ying, Berger, James M., Doudna, Jennifer A.

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Structural basis of human TREX1 DNA degradation and autoimmune disease von Zhou, Wen, Richmond-Buccola, Desmond, Wang, Qiannan, Kranzusch, Philip J.

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Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity von Hobbs, Samuel J., Wein, Tanita, Lu, Allen, Morehouse, Benjamin R., Schnabel, Julia, Leavitt, Azita, Yirmiya, Erez, Sorek, Rotem, Kranzusch, Philip J.

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eIF3 targets cell-proliferation messenger RNAs for translational activation or repression von Lee, Amy S. Y., Kranzusch, Philip J., Cate, Jamie H. D.

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Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance von Zhou, Wen, Whiteley, Aaron T., de Oliveira Mann, Carina C., Morehouse, Benjamin R., Nowak, Radosław P., Fischer, Eric S., Gray, Nathanael S., Mekalanos, John J., Kranzusch, Philip J.

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Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity von Nuñez, James K, Kranzusch, Philip J, Noeske, Jonas, Wright, Addison V, Davies, Christopher W, Doudna, Jennifer A

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Tracing the evolutionary origins of antiviral immunity von Eaglesham, James B, Kranzusch, Philip J

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What bacterial cell death teaches us about life von Johnson, Alex G, Kranzusch, Philip J

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Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict von Eaglesham, James B, McCarty, Kacie L, Kranzusch, Philip J

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A bacterial Argonaute with noncanonical guide RNA specificity von Kaya, Emine, Doxzen, Kevin W., Knoll, Kilian R., Wilson, Ross C., Strutt, Steven C., Kranzusch, Philip J., Doudna, Jennifer A.

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The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products von Garb, Jeremy, Amitai, Gil, Lu, Allen, Ofir, Gal, Brandis, Alexander, Mehlman, Tevie, Kranzusch, Philip J, Sorek, Rotem

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Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity von Kranzusch, Philip J., Lee, Amy S.Y., Wilson, Stephen C., Solovykh, Mikhail S., Vance, Russell E., Berger, James M., Doudna, Jennifer A.

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cGAS and CD-NTase enzymes: structure, mechanism, and evolution von Kranzusch, Philip J

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A microbial transporter of the dietary antioxidant ergothioneine von Dumitrescu, Daniel G., Gordon, Elizabeth M., Kovalyova, Yekaterina, Seminara, Anna B., Duncan-Lowey, Brianna, Forster, Emily R., Zhou, Wen, Booth, Carmen J., Shen, Aimee, Kranzusch, Philip J., Hatzios, Stavroula K.

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Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates von Carey, Clayton M., Govande, Apurva A., Cooper, Juliane M., Hartley, Melissa K., Kranzusch, Philip J., Elde, Nels C.

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Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine von Kimura, Satoshi, Srisuknimit, Veerasak, McCarty, Kacie L., Dedon, Peter C., Kranzusch, Philip J., Waldor, Matthew K.

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