Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker von Solca, Flavio, Dahl, Goeran, Zoephel, Andreas, Bader, Gerd, Sanderson, Michael, Klein, Christian, Kraemer, Oliver, Himmelsbach, Frank, Haaksma, Eric, Adolf, Guenther R

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HDACi – Targets beyond chromatin von Buchwald, Marc, Krämer, Oliver H, Heinzel, Thorsten

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Histone deacetylase inhibitors induce proteolysis of activated CDC42-associated kinase-1 in leukemic cells von Mahendrarajah, Nisintha, Paulus, Ramin, Krämer, Oliver H.

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A phosphorylation-acetylation switch regulates STAT1 signaling von Krämer, Oliver H, Knauer, Shirley K, Greiner, Georg, Jandt, Enrico, Reichardt, Sigrid, Gührs, Karl-Heinz, Stauber, Roland H, Böhmer, Frank D, Heinzel, Thorsten

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SUMOylation regulates the intracellular fate of ZO-2 von Wetzel, Franziska, Mittag, Sonnhild, Cano-Cortina, Misael, Wagner, Tobias, Krämer, Oliver H., Niedenthal, Rainer, Gonzalez-Mariscal, Lorenza, Huber, Otmar

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MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib von Wirth, Matthias, Stojanovic, Natasa, Christian, Jan, Paul, Mariel C, Stauber, Roland H, Schmid, Roland M, Häcker, Georg, Krämer, Oliver H, Saur, Dieter, Schneider, Günter

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Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells von Noack, Katrin, Mahendrarajah, Nisintha, Hennig, Dorle, Schmidt, Luisa, Grebien, Florian, Hildebrand, Dagmar, Christmann, Markus, Kaina, Bernd, Sellmer, Andreas, Mahboobi, Siavosh, Kubatzky, Katharina, Heinzel, Thorsten, Krämer, Oliver H.

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Breakdown of the FLT3-ITD/STAT5 axis and synergistic apoptosis induction by the histone deacetylase inhibitor panobinostat and FLT3-specific inhibitors von Pietschmann, Kristin, Bolck, Hella Anna, Buchwald, Marc, Spielberg, Steffi, Polzer, Harald, Spiekermann, Karsten, Bug, Gesine, Heinzel, Thorsten, Böhmer, Frank-Dietmar, Krämer, Oliver H

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Dataset of the frequency patterns of publications annotated to human protein-coding genes, their protein products and genetic relevance von Zwick, Matthias, Kraemer, Oliver, Carter, Adrian J.

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Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53‐independent pancreatic cancer cell death von Conradt, Laura, Henrich, Annika, Wirth, Matthias, Reichert, Maximilian, Lesina, Marina, Algül, Hana, Schmid, Roland M., Krämer, Oliver H., Saur, Dieter, Schneider, Günter

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Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing’s sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-ind... von Sonnemann, Jürgen, Kahl, Melanie, Siranjeevi, Priyanka M., Blumrich, Annelie, Blümel, Lisa, Becker, Sabine, Wittig, Susan, Winkler, René, Krämer, Oliver H., Beck, James F.

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Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress von Brandl, André, Wagner, Tobias, Uhlig, Katharina M, Knauer, Shirley K, Stauber, Roland H, Melchior, Frauke, Schneider, Günter, Heinzel, Thorsten, Krämer, Oliver H

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Arginine residues within the DNA binding domain of STAT3 promote intracellular shuttling and phosphorylation of STAT3 von Ginter, Torsten, Fahrer, Jörg, Kröhnert, Ulrike, Fetz, Verena, Garrone, Alessio, Stauber, Roland H., Reichardt, Werner, Müller-Newen, Gerhard, Kosan, Christian, Heinzel, Thorsten, Krämer, Oliver H.

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Interferon alpha-armed nanoparticles trigger rapid and sustained STAT1-dependent anti-viral cellular responses von Pollok, Sibyll, Ginter, Torsten, Günzel, Katharina, Pieper, Jana, Henke, Andreas, Stauber, Roland H., Reichardt, Werner, Krämer, Oliver H.

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Acetylation of non-histone proteins modulates cellular signalling at multiple levels von Spange, Stephanie, Wagner, Tobias, Heinzel, Thorsten, Krämer, Oliver H.

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Drugging the HDAC6–HSP90 interplay in malignant cells von Krämer, Oliver H, Mahboobi, Siavosh, Sellmer, Andreas

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Interstrand Crosslink Repair as a Target for HDAC Inhibition von Nikolova, Teodora, Kiweler, Nicole, Krämer, Oliver H.

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Target 2035: probing the human proteome von Carter, Adrian J., Kraemer, Oliver, Zwick, Matthias, Mueller-Fahrnow, Anke, Arrowsmith, Cheryl H., Edwards, Aled M.

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Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis von Wagner, Tobias, Brand, Peter, Heinzel, Thorsten, Krämer, Oliver H.

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The PP2A subunit PR130 is a key regulator of cell development and oncogenic transformation von Dzulko, Melanie, Pons, Miriam, Henke, Andreas, Schneider, Günter, Krämer, Oliver H.

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