Does Cancer of Unknown Primary (CUP) Truly Exist as a Distinct Cancer Entity? von Bochtler, Tilmann, Krämer, Alwin

Volltext

Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Origin: Retrospective Molecular Classification Considering the CUPISCO Study Design von Ross, Jeffrey S., Sokol, Ethan S., Moch, Holger, Mileshkin, Linda, Baciarello, Giulia, Losa, Ferran, Beringer, Andreas, Thomas, Marlene, Elvin, Julia A., Ngo, Nhu, Jin, Dexter X., Krämer, Alwin

Volltext

Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues von Cosenza, Marco Raffaele, Krämer, Alwin

Volltext

Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial von Cortes, Jorge, Perl, Alexander E, Döhner, Hartmut, Kantarjian, Hagop, Martinelli, Giovanni, Kovacsovics, Tibor, Rousselot, Philippe, Steffen, Björn, Dombret, Hervé, Estey, Elihu, Strickland, Stephen, Altman, Jessica K, Baldus, Claudia D, Burnett, Alan, Krämer, Alwin, Russell, Nigel, Shah, Neil P, Smith, Catherine C, Wang, Eunice S, Ifrah, Norbert, Gammon, Guy, Trone, Denise, Lazzaretto, Deborah, Levis, Mark

Volltext

HDP-101, an Anti-BCMA Antibody-Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells von Figueroa-Vazquez, Vianihuini, Ko, Jonathan, Breunig, Christian, Baumann, Anja, Giesen, Nicola, Pálfi, Anikó, Müller, Christoph, Lutz, Christian, Hechler, Torsten, Kulke, Michael, Müller-Tidow, Carsten, Krämer, Alwin, Goldschmidt, Hartmut, Pahl, Andreas, Raab, Marc S

Volltext

Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results von Heuser, Michael, Palmisiano, Neil, Mantzaris, Ioannis, Mims, Alice, DiNardo, Courtney, Silverman, Lewis R., Wang, Eunice S., Fiedler, Walter, Baldus, Claudia, Schwind, Sebastian, Pardee, Timothy, Perl, Alexander E., Cai, Charles, Kaulfuss, Stefan, Lagkadinou, Eleni, Rentzsch, Christine, Wagner, Markus, Wilkinson, Gary, Wu, Bingyan, Jeffers, Michael, Genvresse, Isabelle, Krämer, Alwin

Volltext

The RUNX1 database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy von Homan, Claire C, King-Smith, Sarah L, Lawrence, David M, Arts, Peer, Feng, Jinghua, Andrews, James, Armstrong, Mark, Ha, Thuong, Dobbins, Julia, Drazer, Michael W, Yu, Kai, Bödör, Csaba, Cantor, Alan, Cazzola, Mario, Degelman, Erin, DiNardo, Courtney D, Duployez, Nicolas, Favier, Remi, Fröhling, Stefan, Fitzgibbon, Jude, Klco, Jeffery M, Krämer, Alwin, Kurokawa, Mineo, Lee, Joanne, Malcovati, Luca, Morgan, Neil V, Natsoulis, Georges, Owen, Carolyn, Patel, Keyur P, Preudhomme, Claude, Raslova, Hana, Rienhoff, Hugh, Ripperger, Tim, Schulte, Rachael, Tawana, Kiran, Velloso, Elvira, Yan, Benedict, Liu, Paul, Godley, Lucy A, Schreiber, Andreas W, Hahn, Christopher N, Scott, Hamish S, Brown, Anna L

Volltext

Sorafenib in Combination With Intensive Chemotherapy in Elderly Patients With Acute Myeloid Leukemia: Results From a Randomized, Placebo-Controlled Trial von SERVE, Hubert, KRUG, Utz, FISCHER, Thomas, GIAGOUNIDIS, Aristoteles, NEUBAUER, Andreas, REICHLE, Albrecht, AULITZKY, Walter, NOPPENEY, Richard, BLAU, Igor, KUNZMANN, Volker, STUHLMANN, Reingard, KRÄMER, Alwin, WAGNER, Ruth, KREUZER, Karl-Anton, BRANDTS, Christian, STEFFEN, Björn, THIEDE, Christian, MÜLLER-TIDOW, Carsten, EHNINGER, Gerhard, BERDEL, Wolfgang E, SAUERLAND, M. Cristina, HEINECKE, Achim, BRUNNBERG, Uta, SCHAICH, Markus, OTTMANN, Oliver, DUYSTER, Justus, WANDT, Hannes

Volltext

Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen von REBACZ, Blanka, LARSEN, Thomas O, CLAUSEN, Mads H, RØNNEST, Mads H, LÖFFLER, Harald, HO, Anthony D, KRÄMER, Alwin

Volltext

The clinical mutatome of core binding factor leukemia von Opatz, Sabrina, Bamopoulos, Stefanos A., Metzeler, Klaus H., Herold, Tobias, Ksienzyk, Bianka, Bräundl, Kathrin, Tschuri, Sebastian, Vosberg, Sebastian, Konstandin, Nikola P., Wang, Christine, Hartmann, Luise, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Schneider, Stephanie, Thiede, Christian, Middeke, Jan Moritz, Stölzel, Friedrich, Röllig, Christoph, Schetelig, Johannes, Ehninger, Gerhard, Krämer, Alwin, Braess, Jan, Görlich, Dennis, Sauerland, Maria Cristina, Berdel, Wolfgang E., Wörmann, Bernhard J., Hiddemann, Wolfgang, Spiekermann, Karsten, Bohlander, Stefan K., Greif, Philipp A.

Volltext

A Challenging Task: Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guidelines: The CUPISCO Trial Experience von Pauli, Chantal, Bochtler, Tilmann, Mileshkin, Linda, Baciarello, Giulia, Losa, Ferran, Ross, Jeffrey S., Pentheroudakis, George, Zarkavelis, George, Yalcin, Suayib, Özgüroğlu, Mustafa, Beringer, Andreas, Scarato, Jeremy, Mueller‐Ohldach, Mathis, Thomas, Marlene, Moch, Holger, Krämer, Alwin

Volltext

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease von Karakaya, Kadin, Ball, Claudia, Ott, Marion G, Seger, Reinhard, Schultze-Strasser, Stephan, Grez, Manuel, Koehl, Ulrike, Preiss, Carolin, Kinner, Andrea, von Kalle, Christof, Stein, Stefan, Schwäble, Joachim, Kühlcke, Klaus, Göhring, Gudrun, Jauch, Anna, Martin, Hans, Schwarzwaelder, Kerstin, Schmidt, Manfred, Yang, Rongxi, Thrasher, Adrian J, Tchatchou, Sandrine, Glimm, Hanno, Krämer, Alwin, Schlegelberger, Brigitte, Reinecke, Petra, Hofmann, Wolf-Karsten, Burwinkel, Barbara, Hoelzer, Dieter

Volltext

STIL overexpression shortens lifespan and reduces tumor formation in mice von Moussa, Amira-Talaat, Cosenza, Marco R, Wohlfromm, Timothy, Brobeil, Katharina, Hill, Anthony, Patrizi, Annarita, Müller-Decker, Karin, Holland-Letz, Tim, Jauch, Anna, Kraft, Bianca, Krämer, Alwin

Volltext

Centrosome clustering and chromosomal (in)stability: A matter of life and death von Krämer, Alwin, Maier, Bettina, Bartek, Jiri

Volltext

Nivolumab and ipilimumab in recurrent or refractory cancer of unknown primary: a phase II trial von Pouyiourou, Maria, Kraft, Bianca N., Wohlfromm, Timothy, Stahl, Michael, Kubuschok, Boris, Löffler, Harald, Hacker, Ulrich T., Hübner, Gerdt, Weiss, Lena, Bitzer, Michael, Ernst, Thomas, Schütt, Philipp, Hielscher, Thomas, Delorme, Stefan, Kirchner, Martina, Kazdal, Daniel, Ball, Markus, Kluck, Klaus, Stenzinger, Albrecht, Bochtler, Tilmann, Krämer, Alwin

Volltext

Does time from diagnosis to treatment affect the prognosis of patients with newly diagnosed acute myeloid leukemia? von Röllig, Christoph, Kramer, Michael, Schliemann, Christoph, Mikesch, Jan-Henrik, Steffen, Björn, Krämer, Alwin, Noppeney, Richard, Schäfer-Eckart, Kerstin, Krause, Stefan W., Hänel, Mathias, Herbst, Regina, Kunzmann, Volker, Einsele, Hermann, Jost, Edgar, Brümmendorf, Tim H., Scholl, Sebastian, Hochhaus, Andreas, Neubauer, Andreas, Sohlbach, Kristina, Fransecky, Lars, Kaufmann, Martin, Niemann, Dirk, Schaich, Markus, Frickhofen, Norbert, Kiani, Alexander, Heits, Frank, Krümpelmann, Ulrich, Kaiser, Ulrich, Kullmer, Johannes, Wass, Maxi, Stölzel, Friedrich, von Bonin, Malte, Middeke, Jan Moritz, Thiede, Christian, Schetelig, Johannes, Berdel, Wolfgang E., Ehninger, Gerhard, Baldus, Claudia D., Müller-Tidow, Carsten, Platzbecker, Uwe, Serve, Hubert, Bornhäuser, Martin

Volltext

STIL is required for centriole duplication in human cells von Vulprecht, Julia, David, Ahuvit, Tibelius, Alexandra, Castiel, Asher, Konotop, Gleb, Liu, Fengying, Bestvater, Felix, Raab, Marc S, Zentgraf, Hanswalter, Izraeli, Shai, Krämer, Alwin

Volltext

Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial von Röllig, Christoph, Serve, Hubert, Noppeney, Richard, Hanoun, Maher, Krug, Utz, Baldus, Claudia D., Brandts, Christian H., Kunzmann, Volker, Einsele, Hermann, Krämer, Alwin, Müller-Tidow, Carsten, Schäfer-Eckart, Kerstin, Neubauer, Andreas, Burchert, Andreas, Giagounidis, Aristoteles, Krause, Stefan W., Mackensen, Andreas, Aulitzky, Walter, Herbst, Regina, Hänel, Mathias, Frickhofen, Norbert, Kullmer, Johannes, Kaiser, Ulrich, Kiani, Alexander, Link, Hartmut, Geer, Thomas, Reichle, Albrecht, Junghanß, Christian, Repp, Roland, Meinhardt, Achim, Dürk, Heinz, Klut, Ina-Maria, Bornhäuser, Martin, Schaich, Markus, Parmentier, Stefani, Görner, Martin, Thiede, Christian, von Bonin, Malte, Platzbecker, Uwe, Schetelig, Johannes, Kramer, Michael, Berdel, Wolfgang E., Ehninger, Gerhard

Volltext

Pharmacological Inhibition of Centrosome Clustering by Slingshot-Mediated Cofilin Activation and Actin Cortex Destabilization von Konotop, Gleb, Bausch, Elena, Nagai, Tomoaki, Turchinovich, Andrey, Becker, Natalia, Benner, Axel, Boutros, Michael, Mizuno, Kensaku, Krämer, Alwin, Raab, Marc Steffen

Volltext

Requirement for CDK6 in MLL-rearranged acute myeloid leukemia von Placke, Theresa, Faber, Katrin, Nonami, Atsushi, Putwain, Sarah L., Salih, Helmut R., Heidel, Florian H., Krämer, Alwin, Root, David E., Barbie, David A., Krivtsov, Andrei V., Armstrong, Scott A., Hahn, William C., Huntly, Brian J., Sykes, Stephen M., Milsom, Michael D., Scholl, Claudia, Fröhling, Stefan

Volltext