Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Sele... von Hlaváč, Matúš, Kováčiková, Lucia, Prnová, Marta Šoltésová, Šramel, Peter, Addová, Gabriela, Májeková, Magdaléna, Hanquet, Gilles, Boháč, Andrej, Štefek, Milan

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Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications von Kovacikova, Lucia, Prnova, Marta Soltesova, Majekova, Magdalena, Bohac, Andrej, Karasu, Cimen, Stefek, Milan

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Cu(II) mediated oxidation of cemtirestat yields its disulfide under physiological conditions in vitro von Bodo, Pavol, Kovacikova, Lucia, Bohac, Andrej, Stefek, Milan

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Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket von Hlaváč, Matúš, Kováčiková, Lucia, Šoltésová Prnová, Marta, Addová, Gabriela, Hanquet, Gilles, Štefek, Milan, Boháč, Andrej

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Non-acidic bifunctional benzothiazole-based thiazolidinones with antimicrobial and aldose reductase inhibitory activity as a promising therapeutic strategy for sepsis von Kousaxidis, Antonios, Kovacikova, Lucia, Nicolaou, Ioannis, Stefek, Milan, Geronikaki, Athina

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Selectivity of N(2)-substituted oxotriazinoindole aldose reductase inhibitors is determined by the interaction pattern with Pro301-Arg312 loop of aldehyde reductase von Kováčiková, Lucia, Gaikwad, Sunil, Almášiová, Kristína, Almássy, Ambroz, Addová, Gabriela, Májeková, Magdaléna, Hanquet, Gilles, Dobričić, Vladimir, Boháč, Andrej, Štefek, Milan

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Bringing Capacity Back In: Paradiplomacy and Sub-State Government Internationalization in the Global Economy von Kovacikova, Lucia

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Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat—another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic ra... von Prnova, Marta Soltesova, Kovacikova, Lucia, Svik, Karol, Bezek, Stefan, Elmazoğlu, Zübeyir, Karasu, Cimen, Stefek, Milan

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Molecular structure, pKa, lipophilicity, solubility, absorption, polar surface area, and blood brain barrier penetration of some antiangiogenic agents von Remko, Milan, Boháč, Andrej, Kováčiková, Lucia

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New Route of Benzyne Cyclization for Synthesis of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indole Derivatives Avoiding Highly Toxic Aryl Hydrazines von Kovacikova, Lucia, Stefek, Milan

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Selected Methodologies Convenient for the Synthesis of N,5-Diaryloxazole-2-amine Pharmacophore von Lintnerová, Lucia, Kováčiková, Lucia, Hanquet, Gilles, Boháč, Andrej

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CEMTIRESTAT ATTENUATED NEUROLOGICAL DISORDERS IN RAT MODELS OF TYPE I AND TYPE II DIABETES: A BEHAVIORAL STUDY von Prnová, Marta Šoltésová, Švík, Karol, Bezek, Štefan, Kovaciková, Lucia, Karasu, Cimen, Štefek, Milan

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Inhibitors of SARS-CoV-2 main protease: Biological efficacy and toxicity aspects von Viskupicova, Jana, Rezbarikova, Petronela, Kovacikova, Lucia, Kandarova, Helena, Majekova, Magdalena

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Rational design and synthesis of novel N-benzylindole-based epalrestat analogs as selective aldose reductase inhibitors: An unexpected discovery of a new glucose-lowering agent (AK... von Kousaxidis, Antonios, Paoli, Paolo, Kovacikova, Lucia, Genovese, Massimo, Santi, Alice, Stefek, Milan, Petrou, Anthi, Nicolaou, Ioannis

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An updates: Oxidative aromatization of THβC to β-carbolines and their application for the β-carboline alkaloids synthesis von Gaikwad, Sunil, Kováčiková, Lucia, Pawar, Priyanka, Gaikwad, Milind, Boháč, Andrej, Dawane, Bhaskar

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Beyond Buildings: Social Bargaining and Effective Access to Public Services von Bauhr, Monika, Carlitz, Ruth, Kovacikova, Lucia

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Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group von Kratky, Martin, Sramel, Peter, Bodo, Pavol, Prnova, Marta Soltesova, Kovacikova, Lucia, Majekova, Magdalena, Vinsova, Jarmila, Stefek, Milan

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3-Mercapto-5H-1,2,4-Triazino[5,6-b]Indole-5-Acetic Acid (Cemtirestat) Alleviates Symptoms of Peripheral Diabetic Neuropathy in Zucker Diabetic Fatty (ZDF) Rats: A Role of Aldose Re... von Soltesova Prnova, Marta, Svik, Karol, Bezek, Stefan, Kovacikova, Lucia, Karasu, Cimen, Stefek, Milan

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Synthesis of 3-phenyl-2H,5H-pyrano[3,2-c]chromen-2-one derivatives and their antineoplastic activity von Gasparova, Renata, Kušnierová, Lucia, Boháč, Andrej, Ďurana, Marián, Lácová, Margita

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Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl–sulfonyl–phenols von Koutsopoulos, Konstantinos, Lavrentaki, Vasiliki, Antoniou, Ioakeim, Kousaxidis, Antonios, Lefkopoulou, Matina, Tsantili-Kakoulidou, Anna, Kovacikova, Lucia, Stefek, Milan, Nicolaou, Ioannis

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