Arsenic Trioxide Abrogate MN1 Mediated RA-Resistance in Acute Promyelocytic Leukemia von Pereira-Martins, Diego A, Coelho-Silva, Juan L, Weinhäuser, Isabel, Koury, Luisa C A, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Heuser, Michael, Löwenberg, Bob, Valk, Peter, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo M

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Clinical and Functional Studies Reveal That TP73 Isoforms Levels Are Associated with Prognosis and RA-Resistance in Acute Promyelocytic Leukemia von Ortiz Rojas, César Alexander, Pereira-Martins, Diego A, Weinhäuser, Isabel, Almeida, Luciana Yamamoto, Bianco, Thiago Mantello, Figueiredo-Pontes, Lorena Lobo, Koury, Luisa C A, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M

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Combining Gene Mutation with Gene Expression Data Improves Outcomes Prediction in Acute Promyelocytic Leukemia von Lucena-Araujo, Antonio R., Pereira-Martins, Diego A, Koury, Luisa C A, Coelho-Silva, Juan Luiz, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Chiattone, Carlos, Fagundes, Evandro Maranhão, Chauffaille, Maria de Lourdes, Schrier, Stanley L., Tallman, Martin S., Ribeiro, Raul C., Grimwade, David, Ganser, Arnold, Lowenberg, Bob, Lo Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo Magalhães

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Abstract A39: Nuclear SET domain (NSD) protein lysine methyltransferases (KMT) are higher expressed in acute myeloid leukemia von Wagatsuma, Virginia Mara de Deus, Koury, Luisa C. A., Sánchez, Silvia Helena, Figueiredo-Pontes, Lorena Lobo, Silva, Fernanda Borges da, Dore, Adriana Ines, Lima, Ana Silvia Gouvea de, Lucena-Araujo, Antonio Roberto, Traina, Fabiola, Saldanha-Araujo, Felipe, Pittella, Fabio, Rego, Eduardo Magalhães

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Metformintreatment Overcomes ATRA-Resistance in Acute Promyelocytic Leukemia and Increases FOXO3A Expression von Pereira-Martins, Diego Antonio, Ortiz, Cesar, Franca-Neto, Pedro Luis, Weinhäuser, Isabel, Schiavinato, Josiane Lilian, Palma, Patrícia Vianna Bonini, Bonaldo, Camila, Koury, Luisa C A, Do Nascimento, Mariane Cristina, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B B, Pasquini, Ricardo, Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Ganser, Arnold, Lowenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo Magalhães

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Association between Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Expression and Poor Prognosis in Acute Promyelocytic Leukemia (APL) Patients Treated with ATRA... von De Deus Wagatsuma, Virginia Mara, Pereira-Martins, Diego A, Sánchez Mendoza, Silvia Elena, Koury, Luisa C A, Nascimento, Mariane Cristina, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Pasquini, Ricardo, Chiattone, Carlos, Fagundes, Evandro Maranhão, Chauffaille, Maria de Lourdes, Lucena-Araujo, Antonio R., Tallman, Martin S., Schrier, Stanley L., Ribeiro, Raul C., Ganser, Arnold, Lowenberg, Bob, Lo Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo Magalhães

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The Use of Cyclosporine in Association with Chemotherapy As Induction Treatment in Patients with Acute Myeloid Leukemia (AML) and High Rhodamine Efflux at Diagnosis Results in High... von Koury, Luisa C A, Figueiredo-Pontes, Lorena Lobo, Simoes, Belinda Pinto, Oliveira, Luciana C O, Dalmazzo, Leandro F F, Pintão, Maria Carolina Tostes, Garcia, Aglair B, Falcão, Roberto Passetto, Rego, Eduardo Magalhães

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Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia von De Deus Wagatsuma, Virginia Mara, Koury, Luisa C A, Sánchez, Silvia Elena, Pontes, Lorena Lobo Figueiredo, da Silva, Fernanda Borges, Dore, Adriana Ines, Gouvêa de Lima, Ana Silvia, Lucena-Araujo, Antonio R., Almeida, Luciana Yamamoto, Traina, Fabiola, Saldanha-Araújo, Felipe, Pittella-Silva, Fabio, Rego, Eduardo Magalhães

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Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia von Lucena-Araujo, Antonio R., Coelho-Silva, Juan L., Pereira-Martins, Diego A., Silveira, Douglas R., Koury, Luisa C., Melo, Raul A.M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, de Lourdes Chauffaille, Maria, Bendit, Israel, Rocha, Vanderson, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, P.J.M., Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M.

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Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia von Pereira‐Martins, Diego A., Coelho‐Silva, Juan L., Weinhäuser, Isabel, Franca‐Neto, Pedro L., Silveira, Douglas R., Ortiz, César, Moreira‐Aguiar, Amanda, Lima, Marinus M., Koury, Luisa C., Melo, Raul A., Glória, Ana B., Fagundes, Evandro M., Lino, Bruno K., Pagnano, Katia, Bittencourt, Rosane, Nunes, Elenaide, Traina, Fabiola, Figueiredo‐Pontes, Lorena, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dilon, Richard, Ganser, Arnold, Sanz, Miguel A., Berliner, Nancy, Valk, Peter, Löwenberg, Bob, Ottone, Tiziana, Noguera, Nelida I., Voso, Maria T., Paoloni, Francesca, Fazi, Paola, Ammatuna, Emanuele, Huls, Gerwin, Schuringa, Jan Jacob, Rego, Eduardo M., Lucena‐Araujo, Antonio R.

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STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells von Vicari, Hugo Passos, Coelho-Silva, Juan Luiz, Pereira-Martins, Diego A., Lucena-Araujo, Antônio Roberto, Lima, Keli, Lipreri da Silva, Jean Carlos, Scheucher, Priscila Santos, Koury, Luisa C., de Melo, Raul A., Bittencourt, Rosane, Pagnano, Katia, Nunes, Elenaide, Fagundes, Evandro M., Kerbauy, Fabio, de Figueiredo-Pontes, Lorena Lobo, Costa-Lotufo, Leticia Veras, Rego, Eduardo Magalhães, Traina, Fabiola, Machado-Neto, João Agostinho

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NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia von Thomé, Carolina Hassibe, Ferreira, Germano Aguiar, Pereira-Martins, Diego Antonio, dos Santos, Guilherme Augusto, Ortiz, César Alexander, de Souza, Lucas Eduardo Botelho, Sobral, Lays Martins, Silva, Cleide Lúcia Araújo, Scheucher, Priscila Santos, Gil, Cristiane Damas, Leopoldino, Andréia Machado, Silveira, Douglas R. A., Coelho-Silva, Juan L., Traina, Fabíola, Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana Beatriz F., Kerbauy, Fábio Rodrigues, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Faça, Vitor Marcel, Rego, Eduardo M.

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Clinical Significance of Mitochondrial DNA Content in Acute Promyelocytic Leukemia von Lucena-Araujo, Antonio R., Pereira-Martins, Diego A, Coelho-Silva, Juan L, Weinhäuser, Isabel, Franca-Neto, Pedro Luis, Silveira, Douglas RA, Lima, Marinus M, Schuringa, Jan Jacob, Koury, Luisa C, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Nunes, Elenaide C., Fagundes, Evandro Maranhão, Kerbauy, Fabio R., Figueredo-Pontes, Lorena, Rego, Eduardo M

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Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia von Weinhäuser, Isabel, Pereira-Martins, Diego A., Ortiz, Cesar, Silveira, Douglas R., Simões, Luíse A. A., Bianco, Thiago M., Araujo, Cleide L., Koury, Luisa C., Melo, Raul A. M., Bittencourt, Rosane I., Pagnano, Katia, Pasquini, Ricardo, Nunes, Elenaide C., Fagundes, Evandro M., Gloria, Ana B., Kerbauy, Fábio, Chauffaille, Maria de Lourdes, Keating, Armand, Tallman, Martin S., Ribeiro, Raul C., Dillon, Richard, Ganser, Arnold, Löwenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Ammatuna, Emanuele, Lucena-Araujo, Antonio R., Schuringa, Jan Jacob, Rego, Eduardo M.

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Slit-Robo Pathway Is Clinically Relevant and May Represent a Potential Target in Acute Promyelocytic Leukemia von Weinhäuser, Isabel, Pereira-Martins, Diego Antonio, Ortiz, Cesar, Schiavinato, Josiane Lilian, Bonaldo, Camila, Koury, Luisa C, De Deus Wagatsuma, Virginia Mara, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pagnano, Katia B, Fagundes, Evandro Maranhão, Gloria, Ana Beatriz F., Kerbauy, Fabio R., Chauffaille, Maria de Lourdes, Pasquini, Ricardo, Tallman, Martin S., Ribeiro, Raul, Dillon, Richard, Keating, Armand, Ganser, Arnold, Lowenberg, Bob, Valk, Peter, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Lucena-Araujo, Antonio R., Rego, Eduardo Magalhães

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Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia von Lucena-Araujo, Antonio R., Pereira-Martins, Diego A., Koury, Luisa C., Franca-Neto, Pedro L., Coelho-Silva, Juan L., de Deus Wagatsuma, Virginia M., Melo, Raul A.M., Bittencourt, Rosane, Pagnano, Katia, Pasquini, Ricardo, Chiattone, Carlos S., Fagundes, Evandro M., Chauffaille, Maria de Lourdes, Schrier, Stanley L., Tallman, Martin S., Ribeiro, Raul C., Grimwade, David, Ganser, Arnold, Löwenberg, Bob, Lo-Coco, Francesco, Sanz, Miguel A., Berliner, Nancy, Rego, Eduardo M.

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Low-stringency PCR provides an internal control for negative results in PCR-based diagnosis von de Caballero, O L, Dias Neto, E, Koury, M C, Romanha, A J, Simpson, A J

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