Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases von Calvier, Laurent, Drelich, Aleksandra, Hsu, Jason, Tseng, Chien-Te, Mina, Yair, Nath, Avindra, Kounnas, Maria Z, Herz, Joachim

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Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines von Pontecorvi, Paola, Banki, Michael A, Zampieri, Carlotta, Zalfa, Cristina, Azmoon, Pardis, Kounnas, Maria Z, Marchese, Cinzia, Gonias, Steven L, Mantuano, Elisabetta

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Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases von Calvier, Laurent, Alexander, Anna, Marckx, Austin T, Kounnas, Maria Z, Durakoglugil, Murat, Herz, Joachim

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Reelin Depletion Protects Against Atherosclerosis by Decreasing Vascular Adhesion of Leukocytes von Calvier, Laurent, Xian, Xunde, Lee, Richard G., Sacharidou, Anastasia, Mineo, Chieko, Shaul, Philip W., Kounnas, Maria Z., Tsai, Shirling, Herz, Joachim

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Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism von Vetrivel, Kulandaivelu S, Gong, Ping, Bowen, James W, Cheng, Haipeng, Chen, Ying, Carter, Meghan, Nguyen, Phuong D, Placanica, Lisa, Wieland, Felix T, Li, Yue-Ming, Kounnas, Maria Z, Thinakaran, Gopal

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Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease von Kounnas, Maria Z., Danks, Anne M., Cheng, Soan, Tyree, Curtis, Ackerman, Elizabeth, Zhang, Xulun, Ahn, Kwangwook, Nguyen, Phuong, Comer, Dan, Mao, Long, Yu, Chengzhi, Pleynet, David, Digregorio, Paul J., Velicelebi, Gonul, Stauderman, Kenneth A., Comer, William T., Mobley, William C., Li, Yue-Ming, Sisodia, Sangram S., Tanzi, Rudolph E., Wagner, Steven L.

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Alzheimer Disease Aβ Production in the Absence of S-Palmitoylation-dependent Targeting of BACE1 to Lipid Rafts von Vetrivel, Kulandaivelu S., Meckler, Xavier, Chen, Ying, Nguyen, Phuong D., Seidah, Nabil G., Vassar, Robert, Wong, Philip C., Fukata, Masaki, Kounnas, Maria Z., Thinakaran, Gopal

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NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease von Varvel, Nicholas H, Bhaskar, Kiran, Kounnas, Maria Z, Wagner, Steven L, Yang, Yan, Lamb, Bruce T, Herrup, Karl

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NGP 555, a γ-secretase modulator, lowers the amyloid biomarker, Aβ42, in cerebrospinal fluid while preventing Alzheimer's disease cognitive decline in rodents von Kounnas, Maria Z, Lane-Donovan, Courtney, Nowakowski, Dan W, Herz, Joachim, Comer, William T

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NGP 555, a γ-secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses von Kounnas, Maria Z., Durakoglugil, Murat S., Herz, Joachim, Comer, William T.

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S-Palmitoylation of γ-Secretase Subunits Nicastrin and APH-1 von Cheng, Haipeng, Vetrivel, Kulandaivelu S., Drisdel, Renaldo C., Meckler, Xavier, Gong, Ping, Leem, Jae Yoon, Li, Tong, Carter, Meghan, Chen, Ying, Nguyen, Phuong, Iwatsubo, Takeshi, Tomita, Taisuke, Wong, Philip C., Green, William N., Kounnas, Maria Z., Thinakaran, Gopal

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Mutation Analysis of the Presenilin 1 N-terminal Domain Reveals a Broad Spectrum of γ-Secretase Activity toward Amyloid Precursor Protein and Other Substrates von Gong, Ping, Vetrivel, Kulandaivelu S., Nguyen, Phuong D., Meckler, Xavier, Cheng, Haipeng, Kounnas, Maria Z., Wagner, Steven L., Parent, Angèle T., Thinakaran, Gopal

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Ubiquilin 1 Modulates Amyloid Precursor Protein Trafficking and Aβ Secretion von Hiltunen, Mikko, Lu, Alice, Thomas, Anne V., Romano, Donna M., Kim, Minji, Jones, Phill B., Xie, Zhongcong, Kounnas, Maria Z., Wagner, Steven L., Berezovska, Oksana, Hyman, Bradley T., Tesco, Giuseppina, Bertram, Lars, Tanzi, Rudolph E.

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Reductions in β-amyloid concentrations in vivo by the γ-secretase inhibitors BMS-289948 and BMS-299897 von Anderson, Jeffery J., Holtz, Greg, Baskin, Patricia P., Turner, Mary, Rowe, Blake, Wang, Bowei, Kounnas, Maria Z., Lamb, Bruce T., Barten, Donna, Felsenstein, Kevin, McDonald, Ian, Srinivasan, Kumar, Munoz, Ben, Wagner, Steven L.

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LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation von Kounnas, Maria Z, Moir, Robert D, Rebeck, G.William, Bush, Ashley I, Argraves, W.Scott, Tanzi, Rudolph E, Hyman, Bradley T, Strickland, Dudley K

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NGP 555, a γ-Secretase Modulator, Lowers the Amyloid Biomarker, Aβ 42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents von Kounnas, Maria Z, Lane-Donovan, Courtney, Nowakowski, Dan W, Herz, Joachim, Comer, William T

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Cellular Internalization and Degradation of Antithrombin III-Thrombin, Heparin Cofactor II-Thrombin, and α1-Antitrypsin-Trypsin Complexes Is Mediated by the Low Density Lipoprotein... von Kounnas, Maria Z., Church, Frank C., Argraves, W. Scott, Strickland, Dudley K.

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Identification of Glycoprotein 330 as an Endocytic Receptor for Apolipoprotein J/Clusterin von Kounnas, Maria Z., Loukinova, Elena B., Stefansson, Steingrimur, Harmony, Judith A.K., Brewer, Bryan H., Strickland, Dudley K., Argraves, W. Scott

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Reelin Depletion Protects Against Atherosclerosis by Decreasing Vascular Adhesion of Leukocytes von Calvier, Laurent, Xian, Xunde, Lee, Richard, Sacharidou, Anastasia, Mineo, Chieko, Shaul, Philip W., Kounnas, Maria Z., Tsai, Shirling, Herz, Joachim

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The Cellular Internalization and Degradation of Hepatic Lipase Is Mediated by Low Density Lipoprotein Receptor-related Protein and Requires Cell Surface Proteoglycans von Kounnas, M Z, Chappell, D A, Wong, H, Argraves, W S, Strickland, D K

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