A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases von Ch'ng, J-H, Kotturi, S R, Chong, A G-L, Lear, M J, Tan, K S-W

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Tumor cells expressing a fusion protein of MULT1 and Fas are rejected in vivo by apoptosis and NK cell activation von Kotturi, H S R, Li, J, Branham-O'Connor, M, Stickel, S L, Yu, X, Wagner, T E, Wei, Y

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Fusion induced reversal of dendritic cell maturation: An altered expression of inflammatory chemokine and chemokine receptors in dendritomas von BRANHAM-O'CONNOR, Melissa, JINHUA LI, KOTTURI, Hari S. R, XIANZHONG YU, WAGNER, Thomas E, YANZHANG WEI

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In vitro and in vivo delivery of novel anticancer fusion protein MULT1E/FasTI via adenoviral vectors von Kotturi, H S R, Li, J, Branham-O'Connor, M, Yu, X, Wagner, T E, Wei, Y

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Conducting scaffolds for liver tissue engineering von Tahmasbi Rad, Armin, Ali, Naushad, Kotturi, Hari Shankar R., Yazdimamaghani, Mostafa, Smay, Jim, Vashaee, Daryoosh, Tayebi, Lobat

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A Protective Role for Dengue Virus-Specific CD8+ T Cells von Yauch, Lauren E, Zellweger, Raphael M, Kotturi, Maya F, Qutubuddin, Afrina, Sidney, John, Peters, Bjoern, Prestwood, Tyler R, Sette, Alessandro, Shresta, Sujan

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841P IGM-2323 is a CD20xCD3 IgM bispecific T-cell engager that kills low CD20-expressing and rituximab-resistant B-cell lymphomas von Li, K., Kotturi, M.F., Manlusoc, M., Yun, R., Hinton, P.R., Logronio, K., Baliga, R., Hernandez, G., Sinclair, A.M., Carroll, S.F., Godfrey, W.R., Keyt, B.A.

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Complete genome sequence of Mycobacteriophage Eaglepride von Sahi, Umar, Kottury, Niati G, Kottury, Nirav R, Kotturi, Hari

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CD123 Directed IgM Antibody-based T-cell Engager, IGM-2537, Demonstrates Potent in vitro and in vivo Activity with Minimal Cytokine Release von Liu, Liqin, Li, Gene, Wang, Ling, Yakkundi, Poonam, Hinton, Paul R., Pandya, Deepal, Amoury, Manal, Sekar, Keerthana, Liu, Chian, Rosete, Rodnie, Hanna, Nardeen, Kotturi, Maya F., Bogaert, Liz, Hong, Jiyoung, Tsai, Christina, Keyt, Bruce A., Sinclair, Angus M.

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Igm-2644, a Novel CD38xCD3 Bispecific IgM T Cell Engager Demonstrates Potent Efficacy on Myeloma Cells with an Improved Preclinical Safety Profile von Li, Keyu, Yun, Rui, Chai, Min, Yakkundi, Poonam, Rosete, Rodnie, Li, Gene, Liu, Liqin, Ng, Dean, Hinton, Paul R., Kotturi, Maya F., Sinclair, Angus M., Carroll, Stephen F., Muchhal, Umesh, Keyt, Bruce A.

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Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2 von Somanadhan, Brinda, Kotturi, Santosh R, Yan Leong, Chung, Glover, Robert P, Huang, Yicun, Flotow, Horst, Buss, Antony D, Lear, Martin J, Butler, Mark S

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Sustaining Community-Based Research in Computing: Lessons from Two Tech Capacity Building Initiatives for Local Businesses von Kotturi, Yasmine, Hui, Julie, Johnson, TJ, Sanifu, Lutalo, Dillahunt, Tawanna R.

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Genomic diversity of bacteriophages infecting Microbacterium spp von Jacobs-Sera, Deborah, Abad, Lawrence A, Alvey, Richard M, Anders, Kirk R, Aull, Haley G, Bhalla, Suparna S, Blumer, Lawrence S, Bollivar, David W, Bonilla, J Alfred, Butela, Kristen A, Coomans, Roy J, Cresawn, Steven G, D'Elia, Tom, Diaz, Arturo, Divens, Ashley M, Edgington, Nicholas P, Frederick, Gregory D, Gainey, Maria D, Garlena, Rebecca A, Grant, Kenneth W, Gurney, Susan M R, Hendrickson, Heather L, Hughes, Lee E, Kenna, Margaret A, Klyczek, Karen K, Kotturi, Hari, Mavrich, Travis N, McKinney, Angela L, Merkhofer, Evan C, Moberg Parker, Jordan, Molloy, Sally D, Monti, Denise L, Pape-Zambito, Dana A, Pollenz, Richard S, Pope, Welkin H, Reyna, Nathan S, Rinehart, Claire A, Russell, Daniel A, Shaffer, Christopher D, Sivanathan, Viknesh, Stoner, Ty H, Stukey, Joseph, Sunnen, C Nicole, Tolsma, Sara S, Tsourkas, Philippos K, Wallen, Jamie R, Ware, Vassie C, Warner, Marcie H, Washington, Jacqueline M, Westover, Kristi M, Whitefleet-Smith, JoAnn L, Wiersma-Koch, Helen I, Williams, Daniel C, Zack, Kira M, Hatfull, Graham F

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Coverage of Related Pathogenic Species by Multivalent and Cross-Protective Vaccine Design: Arenaviruses as a Model System von BOTTEN, Jason, SIDNEY, John, MOTHE, Bianca R, PETERS, Bjoern, SETTE, Alessandro, KOTTURI, Maya F

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P815: HIGH VALENCY OF IGM‐2644, A CD38XCD3 IGM BISPECIFIC T CELL ENGAGER, DISPLACES DARATUMUMAB BINDING AND INDUCES POTENT MULTIPLE MYELOMA CELL KILLING von Hart, Kevin C., Santos, Daniel, Pandya, Deepal, Deng, Rong, LI, Keyu, Guan, Yinghui, Hernandez, Genevive, Manley, Thomas, Leabman, Maya K., Hinton, Paul R., Liu, Liqin, Sinclair, Angus M., Candia, Albert F., Carroll, Stephen F., Keyt, Bruce A., Kotturi, Maya F.

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Abstract 52: Mechanistic evaluation of anti-DR5 IgM antibody IGM-8444 with potent tumor cytotoxicity, without in vitro hepatotoxicity von Wang, Beatrice T., Kothambawala, Tasnim, Hart, Kevin C., Chen, Xingjie, Desbois, Melanie, Calhoun, Susan E., Yakkundi, Poonam, Rosete, Rodnie A., Cao, Yuan, Cha, Katie, Matthew, Thomas J., Wang, Ling, Hinton, Paul R., Leabman, Maya K., Hernandez, Genevive, Kotturi, Maya F., Humke, Eric W., Sinclair, Angus M., Keyt, Bruce A.

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Diastereoselective Synthesis of Substituted Tetrahydroquinoline-4-carboxylic Esters by a Tandem Reduction−Reductive Amination Reaction von Bunce, Richard A, Herron, Derrick M, Johnson, Lara B, Kotturi, Sharadsrikar V

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P1276: DOSE RESPONSE PROFILE OF IGM‐2323, A CD20XCD3 IGM BISPECIFIC T CELL ENGAGER, IN TRANSLATIONAL MODELS SUPPORTS PHASE 2 DOSE SELECTION IN NON‐HODGKIN'S LYMPHOMA von Leabman, M. K., Hernandez, G., Ng, C. M., Tang, J., Pandya, D., Hart, K. C., Li, K., Hinton, P. R., So, J., Qazi, I., Cheah, C. Y., Kim, W. S., Budde, E., Gopal, A. K., Manley, T., Takimoto, C. H., Sinclair, A. M., Carroll, S. F., Keyt, B. A., Kotturi, M. F.

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Diverted total synthesis of falcitidin acyl tetrapeptides as new antimalarial leads von Kotturi, Santosh R., Somanadhan, Brinda, Ch’ng, Jun-Hong, Tan, Kevin S.-W., Butler, Mark S., Lear, Martin J.

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A mild method for the protection of alcohols using a para-methoxybenzylthio tetrazole (PMB-ST) under dual acid–base activation von Kotturi, Santosh R., Tan, Jason S., Lear, Martin J.

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