Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling von McCauley, Katherine B., Hawkins, Finn, Serra, Maria, Thomas, Dylan C., Jacob, Anjali, Kotton, Darrell N.

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Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration von Alysandratos, Konstantinos-Dionysios, Herriges, Michael J, Kotton, Darrell N

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Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells von Jacob, Anjali, Vedaie, Marall, Roberts, David A., Thomas, Dylan C., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Hawkins, Finn, Kotton, Darrell N.

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SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response von Huang, Jessie, Hume, Adam J., Abo, Kristine M., Werder, Rhiannon B., Villacorta-Martin, Carlos, Alysandratos, Konstantinos-Dionysios, Beermann, Mary Lou, Simone-Roach, Chantelle, Lindstrom-Vautrin, Jonathan, Olejnik, Judith, Suder, Ellen L., Bullitt, Esther, Hinds, Anne, Sharma, Arjun, Bosmann, Markus, Wang, Ruobing, Hawkins, Finn, Burks, Eric J., Saeed, Mohsan, Wilson, Andrew A., Mühlberger, Elke, Kotton, Darrell N.

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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future von Basil, Maria C, Katzen, Jeremy, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J, Chapman, Hal A, Kotton, Darrell N, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Morrisey, Edward E

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SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes von Li, Yize, Renner, David M., Comar, Courtney E., Whelan, Jillian N., Reyes, Hanako M., Cardenas-Diaz, Fabian Leonardo, Truitt, Rachel, Tan, Li Hui, Dong, Beihua, Alysandratos, Konstantinos Dionysios, Huang, Jessie, Palmer, James N., Adappa, Nithin D., Kohanski, Michael A., Kotton, Darrell N., Silverman, Robert H., Yang, Wenli, Morrisey, Edward E., Cohen, Noam A., Weiss, Susan R.

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Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells von Kurmann, Anita A., Serra, Maria, Hawkins, Finn, Rankin, Scott A., Mori, Munemasa, Astapova, Inna, Ullas, Soumya, Lin, Sui, Bilodeau, Melanie, Rossant, Janet, Jean, Jyh C., Ikonomou, Laertis, Deterding, Robin R., Shannon, John M., Zorn, Aaron M., Hollenberg, Anthony N., Kotton, Darrell N.

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Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 von Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Pretto, Carla D., Qiao, Yuanyuan, Zhang, Yuping, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Chinnaiyan, Arul M., Sexton, Jonathan Z.

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Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells von Longmire, Tyler A., Ikonomou, Laertis, Hawkins, Finn, Christodoulou, Constantina, Cao, Yuxia, Jean, J.C., Kwok, Letty W., Mou, Hongmei, Rajagopal, Jayaraj, Shen, Steven S., Dowton, Anne A., Serra, Maria, Weiss, Daniel J., Green, Michael D., Snoeck, Hans-Willem, Ramirez, Maria I., Kotton, Darrell N.

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Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette von Sommer, Cesar A., Stadtfeld, Matthias, Murphy, George J., Hochedlinger, Konrad, Kotton, Darrell N., Mostoslavsky, Gustavo

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Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells von Hawkins, Finn J., Suzuki, Shingo, Beermann, Mary Lou, Barillà, Cristina, Wang, Ruobing, Villacorta-Martin, Carlos, Berical, Andrew, Jean, J.C., Le Suer, Jake, Matte, Taylor, Simone-Roach, Chantelle, Tang, Yang, Schlaeger, Thorsten M., Crane, Ana M., Matthias, Nadine, Huang, Sarah X.L., Randell, Scott H., Wu, Joshua, Spence, Jason R., Carraro, Gianni, Stripp, Barry R., Rab, Andras, Sorsher, Eric J., Horani, Amjad, Brody, Steven L., Davis, Brian R., Kotton, Darrell N.

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Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells von Mithal, Aditya, Capilla, Amalia, Heinze, Dar, Berical, Andrew, Villacorta-Martin, Carlos, Vedaie, Marall, Jacob, Anjali, Abo, Kristine, Szymaniak, Aleksander, Peasley, Megan, Stuffer, Alexander, Mahoney, John, Kotton, Darrell N., Hawkins, Finn, Mostoslavsky, Gustavo

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Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells von Hawkins, Finn, Kramer, Philipp, Jacob, Anjali, Driver, Ian, Thomas, Dylan C, McCauley, Katherine B, Skvir, Nicholas, Crane, Ana M, Kurmann, Anita A, Hollenberg, Anthony N, Nguyen, Sinead, Wong, Brandon G, Khalil, Ahmad S, Huang, Sarah Xl, Guttentag, Susan, Rock, Jason R, Shannon, John M, Davis, Brian R, Kotton, Darrell N

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Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors von Hurley, Killian, Ding, Jun, Villacorta-Martin, Carlos, Herriges, Michael J., Jacob, Anjali, Vedaie, Marall, Alysandratos, Konstantinos D., Sun, Yuliang L., Lin, Chieh, Werder, Rhiannon B., Huang, Jessie, Wilson, Andrew A., Mithal, Aditya, Mostoslavsky, Gustavo, Oglesby, Irene, Caballero, Ignacio S., Guttentag, Susan H., Ahangari, Farida, Kaminski, Naftali, Rodriguez-Fraticelli, Alejo, Camargo, Fernando, Bar-Joseph, Ziv, Kotton, Darrell N.

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Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells von Dost, Antonella F.M., Moye, Aaron L., Vedaie, Marall, Tran, Linh M., Fung, Eileen, Heinze, Dar, Villacorta-Martin, Carlos, Huang, Jessie, Hekman, Ryan, Kwan, Julian H., Blum, Benjamin C., Louie, Sharon M., Rowbotham, Samuel P., Sainz de Aja, Julio, Piper, Mary E., Bhetariya, Preetida J., Bronson, Roderick T., Emili, Andrew, Mostoslavsky, Gustavo, Fishbein, Gregory A., Wallace, William D., Krysan, Kostyantyn, Dubinett, Steven M., Yanagawa, Jane, Kotton, Darrell N., Kim, Carla F.

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Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors von Geusz, Ryan J., Wang, Allen, Lam, Dieter K., Vinckier, Nicholas K., Alysandratos, Konstantinos-Dionysios, Roberts, David A., Wang, Jinzhao, Kefalopoulou, Samy, Ramirez, Araceli, Qiu, Yunjiang, Chiou, Joshua, Gaulton, Kyle J., Ren, Bing, Kotton, Darrell N., Sander, Maike

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Human alveolar hydrogels promote morphological and transcriptional differentiation in iPSC-derived alveolar type 2 epithelial cells von Hoffman, Evan T., Uriarte, Juan J., Uhl, Franziska E., Eckstrom, Korin, Tanneberger, Alicia E., Becker, Chloe, Moulin, Chloe, Asarian, Loredana, Ikonomou, Laertis, Kotton, Darrell N., Weiss, Daniel J.

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Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease von Alysandratos, Konstantinos-Dionysios, Russo, Scott J., Petcherski, Anton, Taddeo, Evan P., Acín-Pérez, Rebeca, Villacorta-Martin, Carlos, Jean, J.C., Mulugeta, Surafel, Rodriguez, Luis R., Blum, Benjamin C., Hekman, Ryan M., Hix, Olivia T., Minakin, Kasey, Vedaie, Marall, Kook, Seunghyi, Tilston-Lunel, Andrew M., Varelas, Xaralabos, Wambach, Jennifer A., Cole, F. Sessions, Hamvas, Aaron, Young, Lisa R., Liesa, Marc, Emili, Andrew, Guttentag, Susan H., Shirihai, Orian S., Beers, Michael F., Kotton, Darrell N.

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Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification von Serra, Maria, Alysandratos, Konstantinos-Dionysios, Hawkins, Finn, McCauley, Katherine B, Jacob, Anjali, Choi, Jinyoung, Caballero, Ignacio S, Vedaie, Marall, Kurmann, Anita A, Ikonomou, Laertis, Hollenberg, Anthony N, Shannon, John M, Kotton, Darrell N

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Editorial: Progenitors and Stem Cells in Thyroid Development, Disease, and Regeneration von Kotton, Darrell N, Nilsson, Mikael

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