Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations von Kotronen, A, Velagapudi, V. R, Yetukuri, L, Westerbacka, J, Bergholm, R, Ekroos, K, Makkonen, J, Taskinen, M.-R, Orešič, M, Yki-Järvinen, H

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common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans von Kotronen, A, Johansson, L. E, Johansson, L. M, Roos, C, Westerbacka, J, Hamsten, A, Bergholm, R, Arkkila, P, Arola, J, Kiviluoto, T, Fisher, R. M, Ehrenborg, E, Orho-Melander, M, Ridderstråle, M, Groop, L, Yki-Järvinen, H

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Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome von Kotronen, A, Seppälä-Lindroos, A, Bergholm, R, Yki-Järvinen, H

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P1075 : IGFBP-1 Significantly helps in predicting liver fat in NAFLD von Petäjä, E.M, Zhou, Y, Havana, M, Kotronen, A, Ihalainen, J, Yki-Järvinen, H

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CB1 blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans von Bergholm, R, Sevastianova, K, Santos, A, Kotronen, A, Urjansson, M, Hakkarainen, A, Lundbom, J, Tiikkainen, M, Rissanen, A, Lundbom, N, Yki-Järvinen, H

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O27 DOES PNPLA3 INCREASE LIVER FAT BY EXTRA-HEPATIC MECHANISMS? von Lallukka, S, Kotronen, A, Perttilä, J, Olkkonen, V.M, Yki-Järvinen, H

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Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans von Sevastianova, Ksenia, Santos, Alexandre, Kotronen, Anna, Hakkarainen, Antti, Makkonen, Janne, Silander, Kaisa, Peltonen, Markku, Romeo, Stefano, Lundbom, Jesper, Lundbom, Nina, Olkkonen, Vesa M, Gylling, Helena, Fielding, Barbara A, Rissanen, Aila, Yki-Järvinen, Hannele

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104 A CANDIDATE-GENE APPROACH TO VALIDATION OF GENETIC MODIFIER ASSOCIATIONS USING A LARGE COHORT WITH HISTOLOGICALLY CHARACTERISED NON-ALCOHOLIC FATTY LIVER DISEASE von Anstee, Q.M, Darlay, R, Leathart, J, Liu, Y.-L, Tordjman, J, Clement, K, Aithal, G, Valenti, L, Van Gaal, L, Stickel, F, Alison, M, Romero-Gomez, M, Andrade, R, Reeves, H, Bedossa, P, Pihlajamaki, J, Kotronen, A, Yki-Jarvinen, H, Chalasani, N, Kleiner, D.E, Rotter, J, Burt, A, Ratziu, V, Cordell, H.J, Daly, A.K, Day, C.P

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Gene expression in human NAFLD von Greco, Dario, Kotronen, Anna, Westerbacka, Jukka, Puig, Oscar, Arkkila, Perttu, Kiviluoto, Tuula, Laitinen, Saara, Kolak, Maria, Fisher, Rachel M, Hamsten, Anders, Auvinen, Petri, Yki-Järvinen, Hannele

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Long-term effect of bariatric surgery on liver enzymes in the Swedish Obese Subjects (SOS) study von Burza, Maria Antonella, Romeo, Stefano, Kotronen, Anna, Svensson, Per-Arne, Sjöholm, Kajsa, Torgerson, Jarl S, Lindroos, Anna-Karin, Sjöström, Lars, Carlsson, Lena M S, Peltonen, Markku

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Nateglinide combination therapy with basal insulin and metformin in patients with Type 2 diabetes von Juurinen, L., Tiikkainen, M., Saltevo, J., Nikkilä, K., Lanki, H., Leppävuori, E., Kock, T., Teikari-Myyrä, T., Kauppinen-Mäkelin, R., Kotronen, A., Yki-Järvinen, H.

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Insulin-Like Growth Factor Binding Protein 1 as a Novel Specific Marker of Hepatic Insulin Sensitivity von Kotronen, Anna, Lewitt, Moira, Hall, Kerstin, Brismar, Kerstin, Yki-Järvinen, Hannele

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Obesity‐Related Derangements of Coagulation and Fibrinolysis: A Study of Obesity‐Discordant Monozygotic Twin Pairs von Kaye, Sanna M., Pietiläinen, Kirsi H., Kotronen, Anna, Joutsi‐Korhonen, Lotta, Kaprio, Jaakko, Yki‐Järvinen, Hannele, Silveira, Angela, Hamsten, Anders, Lassila, Riitta, Rissanen, Aila

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Splanchnic Balance of Free Fatty Acids, Endocannabinoids, and Lipids in Subjects With Nonalcoholic Fatty Liver Disease von Westerbacka, Jukka, Kotronen, Anna, Fielding, Barbara A, Wahren, John, Hodson, Leanne, Perttilä, Julia, Seppänen–Laakso, Tuulikki, Suortti, Tapani, Arola, Johanna, Hultcrantz, Rolf, Castillo, Sandra, Olkkonen, Vesa M, Frayn, Keith N, Orešič, Matej, Yki–Järvinen, Hannele

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Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts von Kotronen, Anna, Yki-Järvinen, Hannele, Aminoff, Anna, Bergholm, Robert, Pietiläinen, Kirsi H, Westerbacka, Jukka, Talmud, Philippa J, Humphries, Steve E, Hamsten, Anders, Isomaa, Bo, Groop, Leif, Orho-Melander, Marju, Ehrenborg, Ewa, Fisher, Rachel M

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Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans von RAFTER, INGALILL, GRÅBERG, TRULS, KOTRONEN, ANNA, STRÖMMER, LOVISA, MATTSON, C. MIKAEL, KIM, RAY W, EHRENBORG, EWA, ANDERSSON, HÅKAN B, YKI-JÄRVINEN, HANNELE, SCHUPPE-KOISTINEN, INA, EKBLOM, BJÖRN, COTGREAVE, IAN, GLINGHAMMAR, BJÖRN

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blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans von Bergholm, R, Sevastianova, K, Santos, A, Kotronen, A, Urjansson, M, Hakkarainen, A, Lundbom, J, Tiikkainen, M, Rissanen, A, Lundbom, N, Yki- Jarvinen, H

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CB sub(1) blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans von Bergholm, R, Sevastianova, K, Santos, A, Kotronen, A, Urjansson, M, Hakkarainen, A, Lundbom, J, Tiikkainen, M, Rissanen, A, Lundbom, N, Yki-Jaervinen, H

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CB(1) blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans von Bergholm, R, Sevastianova, K, Santos, A, Kotronen, A, Urjansson, M, Hakkarainen, A, Lundbom, J, Tiikkainen, M, Rissanen, A, Lundbom, N, Yki-Järvinen, H

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PO21-632 QUANTIFICATION OF LIVER FAT BY PROTON MAGNETIC RESONANCE SPECTROSCOPY IN 271 SUBJECTS WITH AND WITHOUT THE METABOLIC SYNDROME von Kotronen, A., Westerbacka, J., Bergholm, R., Pietilainen, K.H., Juurinen, L., Yki-Jarvinen, H.

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