A Phase II Trial of Lutikizumab, an Anti–Interleukin‐1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis von Fleischmann, Roy M., Bliddal, Henning, Blanco, Francisco J., Schnitzer, Thomas J., Peterfy, Charles, Chen, Su, Wang, Li, Feng, Sheng, Conaghan, Philip G., Berenbaum, Francis, Pelletier, Jean‐Pierre, Martel‐Pelletier, Johanne, Vaeterlein, Ole, Kaeley, Gurjit S., Liu, Wei, Kosloski, Matthew P., Levy, Gwen, Zhang, Lanju, Medema, Jeroen K., Levesque, Marc C.

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Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis von Dellon, Evan S., Rothenberg, Marc E., Collins, Margaret H., Hirano, Ikuo, Chehade, Mirna, Bredenoord, Albert J., Lucendo, Alfredo J., Spergel, Jonathan M., Aceves, Seema, Sun, Xian, Kosloski, Matthew P., Kamal, Mohamed A., Hamilton, Jennifer D., Beazley, Bethany, McCann, Eilish, Patel, Kiran, Mannent, Leda P., Laws, Elizabeth, Akinlade, Bolanle, Amin, Nikhil, Lim, Wei Keat, Wipperman, Matthew F., Ruddy, Marcella, Patel, Naimish, Weinreich, David R., Yancopoulos, George D., Shumel, Brad, Maloney, Jennifer, Giannelou, Angeliki, Shabbir, Arsalan

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Delivery of Therapeutic Proteins von Pisal, Dipak S., Kosloski, Matthew P., Balu-Iyer, Sathy V.

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Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial von Paller, Amy S, Simpson, Eric L, Siegfried, Elaine C, Cork, Michael J, Wollenberg, Andreas, Arkwright, Peter D, Soong, Weily, Gonzalez, Mercedes E, Schneider, Lynda C, Sidbury, Robert, Lockshin, Benjamin, Meltzer, Steven, Wang, Zhixiao, Mannent, Leda P, Amin, Nikhil, Sun, Yiping, Laws, Elizabeth, Akinlade, Bolanle, Dillon, Myles, Kosloski, Matthew P, Kamal, Mohamed A, Dubost-Brama, Ariane, Patel, Naimish, Weinreich, David M, Yancopoulos, George D, O’Malley, John T, Bansal, Ashish, Pepper, Amber, Cohen, David, Pariser, David, Leflein, Jeffrey, Weinberg, Jeffrey, Browning, John, Teng, Joyce, Wine Lee, Lara, Sher, Lawrence, Diaz, Lucia, Schneider, Lynda, Rupp, Ned, Ong, Peck, Cartwright, Robert, Pinter, Andreas, Schnopp, Christina, Korkosz, Anna, Bystrzanowska, Dorota, Sygula, Ewa, Zdybski, Jacek, Padlewska, Kamila

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Characterizing complex and competing drug–drug interactions between the antiviral regimen of glecaprevir and pibrentasvir with rifampin or carbamazepine von Kosloski, Matthew P., Li, Hong, Wang, Stanley, Mensa, Federico, Kort, Jens, Liu, Wei

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Efficacy and Safety of Glecaprevir/Pibrentasvir in Patients Coinfected With Hepatitis C Virus and Human Immunodeficiency Virus Type 1: The EXPEDITION-2 Study von Rockstroh, Jürgen K, Lacombe, Karine, Viani, Rolando M, Orkin, Chloe, Wyles, David, Luetkemeyer, Anne F, Soto-Malave, Ruth, Flisiak, Robert, Bhagani, Sanjay, Sherman, Kenneth E, Shimonova, Tatiana, Ruane, Peter, Sasadeusz, Joseph, Slim, Jihad, Zhang, Zhenzhen, Samanta, Suvajit, Ng, Teresa I, Gulati, Abhishek, Kosloski, Matthew P, Shulman, Nancy S, Trinh, Roger, Sulkowski, Mark

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Long-Term Efficacy and Safety of Dupilumab in Adolescents with Moderate-to-Severe Atopic Dermatitis: Results Through Week 52 from a Phase III Open-Label Extension Trial (LIBERTY AD... von Blauvelt, Andrew, Guttman-Yassky, Emma, Paller, Amy S., Simpson, Eric L., Cork, Michael J., Weisman, Jamie, Browning, John, Soong, Weily, Sun, Xian, Chen, Zhen, Kosloski, Matthew P., Kamal, Mohamed A., Delevry, Dimittri, Chuang, Chien-Chia, O’Malley, John T., Bansal, Ashish

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Dupilumab: Mechanism of action, clinical, and translational science von McCann, Marc R., Kosloski, Matthew P., Xu, Christine, Davis, John D., Kamal, Mohamed A.

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No Clinically Relevant Drug-Drug Interactions between Methadone or Buprenorphine-Naloxone and Antiviral Combination Glecaprevir and Pibrentasvir von Kosloski, Matthew P, Zhao, Weihan, Asatryan, Armen, Kort, Jens, Geoffroy, Pierre, Liu, Wei

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Translation of In Vitro Transport Inhibition Studies to Clinical Drug-Drug Interactions for Glecaprevir and Pibrentasvir von Kosloski, Matthew P, Bow, Daniel A J, Kikuchi, Ryota, Wang, Haoyu, Kim, Elaine J, Marsh, Kennan, Mensa, Federico, Kort, Jens, Liu, Wei

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Pharmacokinetics and pharmacodynamics of itepekimab in healthy adults and patients with asthma: Phase I first‐in‐human and first‐in‐patient trials von Kosloski, Matthew P., Kalliolias, George D., Xu, Christine R., Harel, Sivan, Lai, Ching‐Ha, Zheng, Wenjun, Davis, John D., Kamal, Mohamed A.

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Effects of Renal Impairment and Hemodialysis on the Pharmacokinetics and Safety of the Glecaprevir and Pibrentasvir Combination in Hepatitis C Virus-Negative Subjects von Kosloski, Matthew P, Zhao, Weihan, Marbury, Thomas C, Preston, Richard A, Collins, Michael G, Pugatch, David, Mensa, Federico, Kort, Jens, Liu, Wei

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Subcutaneous Administration of Monoclonal Antibodies: Pharmacology, Delivery, Immunogenicity, and Learnings From Applications to Clinical Development von Davis, John D., Bravo Padros, Marçal, Conrado, Daniela J., Ganguly, Samit, Guan, Xiaowen, Hassan, Hazem E., Hazra, Anasuya, Irvin, Susan C., Jayachandran, Priya, Kosloski, Matthew P., Lin, Kuan‐Ju, Mukherjee, Kamalika, Paccaly, Anne, Papachristos, Apostolos, Partridge, Michael A., Prabhu, Saileta, Visich, Jennifer, Welf, Erik S., Xu, Xiaoying, Zhao, An, Zhu, Min

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Dupilumab for Eosinophilic Esophagitis in Patients 1 to 11 Years of Age von Chehade, Mirna, Dellon, Evan S., Spergel, Jonathan M., Collins, Margaret H., Rothenberg, Marc E., Pesek, Robert D., Hirano, Ikuo, Liu, Ruiqi, Laws, Elizabeth, Mortensen, Eric, Martincova, Renata, Shabbir, Arsalan, McCann, Eilish, Kamal, Mohamed A., Kosloski, Matthew P., Hamilton, Jennifer D., Samuely, Carin, Lim, Wei Keat, Wipperman, Matthew F., Farrell, Annamaria, Patel, Naimish, Yancopoulos, George D., Glotfelty, Lila, Maloney, Jennifer

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Integrated Exposure–Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis von Briggs, Emily, Kamal, Mohamed A., Kosloski, Matthew P., Linsmeier, Ian, Jusko, Natalie, Dolphin, Nancy, Chittenden, Jason, Simpson, Eric L., Paller, Amy S., Siegfried, Elaine C., Shumel, Brad, Levit, Noah A., Bansal, Ashish, Davis, John D., Chapel, Sunny, Smith, David E., Huniti, Nidal

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Drug-Drug Interactions of Glecaprevir and Pibrentasvir Coadministered With Human Immunodeficiency Virus Antiretrovirals von Kosloski, Matthew P, Oberoi, Rajneet, Wang, Stanley, Viani, Rolando M, Asatryan, Armen, Hu, Beibei, Ding, Bifeng, Qi, Xin, Kim, Elaine J, Mensa, Federico, Kort, Jens, Liu, Wei

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Phase I safety and pharmacokinetics study of rovalpituzumab tesirine in Japanese patients with advanced, recurrent small cell lung cancer von Udagawa, Hibiki, Akamatsu, Hiroaki, Tanaka, Kentaro, Takeda, Masayuki, Kanda, Shintaro, Kirita, Keisuke, Teraoka, Shunsuke, Nakagawa, Kazuhiko, Fujiwara, Yutaka, Yasuda, Ikuko, Okubo, Sumiko, Shintani, Masayuki, Kosloski, Matthew P., Scripture, Charity, Tamura, Tomohide, Okamoto, Isamu

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Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis von Kamal, Mohamed A, Kosloski, Matthew P, Lai, Ching-Ha, Partridge, Michael A, Rajadhyaksha, Manoj, Kanamaluru, Vanaja, Bansal, Ashish, Shabbir, Arsalan, Shumel, Brad, Ardeleanu, Marius, Richards, Susan M, Yan, Hong, Xu, Christine R, Rodríguez-Marco, Ainara, Xiao, Jing, Khokhar, Faisal A, Gherardi, Guy, Babilonia, Elisa, Maloney, Jennifer, Mortensen, Eric, Akinlade, Bolanle, Braunstein, Ned, Stahl, Neil, Torri, Albert, Davis, John D, DiCioccio, A Thomas

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Pharmacokinetics and Tolerability of a Dual Variable Domain Immunoglobulin ABT-981 Against IL-1α and IL-1β in Healthy Subjects and Patients With Osteoarthritis of the Knee von Kosloski, Matthew P., Goss, Sandra, Wang, Susanne X., Liu, Jia, Loebbert, Ralf, Medema, Jeroen K., Liu, Wei, Dutta, Sandeep

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Pharmacokinetics and Tolerability of a Dual Variable Domain Immunoglobulin ABT-981 Against IL-1[alpha] and IL-1[beta] in Healthy Subjects and Patients With Osteoarthritis of the Kn... von Kosloski, Matthew P, Goss, Sandra, Wang, Susanne X, Liu, Jia, Loebbert, Ralf, Medema, Jeroen K, Liu, Wei, Dutta, Sandeep

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