PU.1 eviction at lymphocyte-specific chromatin domains mediates glucocorticoid response in acute lymphoblastic leukemia von Beck, Dominik, Cao, Honghui, Tian, Feng, Huang, Yizhou, Jiang, Miao, Zhao, Han, Tai, Xiaolu, Xu, Wenqian, Kosasih, Hansen J., Kealy, David J., Zhao, Weiye, Taylor, Samuel J., Couttas, Timothy A., Song, Gaoxian, Chacon-Fajardo, Diego, Walia, Yashna, Wang, Meng, Dowle, Adam A., Holding, Andrew N., Bridge, Katherine S., Zhang, Chao, Wang, Jin, Mi, Jian-Qing, Lock, Richard B., de Bock, Charles E., Jing, Duohui

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Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL von Sadras, Teresa, Jalud, Fatimah B., Kosasih, Hansen J., Horne, Christopher R., Brown, Lauren M., El-Kamand, Sam, de Bock, Charles E., McAloney, Lachlan, Ng, Ashley P., Davidson, Nadia M., Ludlow, Louise E. A., Oshlack, Alicia, Cowley, Mark J., Khaw, Seong L., Murphy, James M., Ekert, Paul G.

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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma von De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Reunes, Lindy, Kosasih, Hansen J, Reekmans, Alexandra, Brown, Lauren M, Van Roy, Nadine, Palhais, Bruno, Roels, Juliette, Van der Linden, Malaika, Van Dorpe, Jo, Ntziachristos, Panagiotis, Van Delft, Frederik W, Mansour, Marc R, Pieters, Tim, Lammens, Tim, De Moerloose, Barbara, De Bock, Charles E, Goossens, Steven, Van Vlierberghe, Pieter

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Less is more: Depleting myeloid‐biased HSCs to restore immune function von Kosasih, Hansen J., Bock, Charles E.

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In vitro and in vivo modelling of mutant JAK3/STAT5 signaling in leukemia von Omari, Sofia A., Kosasih, Hansen J., Chung, Thomas, de Bock, Charles E.

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The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia von Toscan, Cara E., McCalmont, Hannah, Ashoorzadeh, Amir, Lin, Xiaojing, Fu, Zhe, Doculara, Louise, Kosasih, Hansen J., Cadiz, Roxanne, Zhou, Anthony, Williams, Sarah, Evans, Kathryn, Khalili, Faezeh, Cai, Ruilin, Yeats, Kristy L., Gifford, Andrew J., Pickford, Russell, Mayoh, Chelsea, Xie, Jinhan, Henderson, Michelle J., Trahair, Toby N., Patterson, Adam V., Smaill, Jeff B., de Bock, Charles E., Lock, Richard B.

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ALLSorts: a RNA-Seq subtype classifier for B-Cell Acute Lymphoblastic Leukemia von Schmidt, Breon, Brown, Lauren M., Ryland, Georgina L., Lonsdale, Andrew, Kosasih, Hansen J., Ludlow, Louise E., Majewski, Ian J., Blombery, Piers, Ekert, Paul G., Davidson, Nadia M., Oshlack, Alicia

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A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax von Kosasih, Hansen J., Healey, Gerry, Brennan, Margs S., Bjelosevic, Stefan, Sadras, Teresa, Jalud, Fatimah B., Ibnat, Tasnia, Ng, Ashley P., Mayoh, Chelsea, Mao, Jie, Tax, Gabor, Ludlow, Louise E. A., Johnstone, Ricky W., Herold, Marco J., Khaw, Seong L., Bock, Charles E., Ekert, Paul G.

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Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL–USP2 fusions von Meyer, Claus, Lopes, Bruno A., Caye-Eude, Aurélie, Cavé, Hélène, Arfeuille, Chloé, Cuccuini, Wendy, Sutton, Rosemary, Venn, Nicola C., Oh, Seung Hwan, Tsaur, Grigory, Escherich, Gabriele, Feuchtinger, Tobias, Kosasih, Hansen J., Khaw, Seong L., Ekert, Paul G., Pombo-de-Oliveira, Maria S., Bidet, Audrey, Djahanschiri, Bardya, Ebersberger, Ingo, Zaliova, Marketa, Zuna, Jan, Zermanova, Zuzana, Juvonen, Vesa, Grümayer, Renate Panzer, Fazio, Grazia, Cazzaniga, Gianni, Larghero, Patrizia, Emerenciano, Mariana, Marschalek, Rolf

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Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions von Ryland, Georgina L., Umeda, Masayuki, Holmfeldt, Linda, Lehmann, Sören, Herlin, Morten Krogh, Ma, Jing, Khanlari, Mahsa, Rubnitz, Jeffrey E., Ries, Rhonda E., Kosasih, Hansen J., Ekert, Paul G., Goh, Hwee Ngee, Tiong, Ing S., Grimmond, Sean M., Haferlach, Claudia, Day, Ryan B., Ley, Timothy J., Meshinchi, Soheil, Ma, Xiaotu, Blombery, Piers, Klco, Jeffery M.

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In vivo activity of the second-generation proteasome inhibitor ixazomib against pediatric T-cell acute lymphoblastic leukemia xenografts von Randall, Joanna, Evans, Kathryn, Watts, Ben, Kosasih, Hansen J., Smith, Christopher M., Earley, Eric J., Erickson, Stephen W., Jocoy, Emily L., Bult, Carol J., Teicher, Beverly A., de Bock, Charles E., Smith, Malcolm A., Lock, Richard B.

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TALLSorts: a T-cell acute lymphoblastic leukemia subtype classifier using RNA-seq expression data von Gu, Allen, Schmidt, Breon, Lonsdale, Andrew, Jalaldeen, Roshan, Kosasih, Hansen J, Brown, Lauren M, Sadras, Teresa, Ekert, Paul G, Oshlack, Alicia

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A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers von Kosasih, Hansen J., Last, Karena, Rogerson, Fraser M., Golub, Suzanne B., Gauci, Stephanie J., Russo, Vincenzo C., Stanton, Heather, Wilson, Richard, Lamande, Shireen R., Holden, Paul, Fosang, Amanda J.

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SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia von Brown, Lauren M., Hediyeh-zadeh, Soroor, Sadras, Teresa, Huckstep, Hannah, Sandow, Jarrod J., Bartolo, Ray C., Kosasih, Hansen J., Davidson, Nadia M., Schmidt, Breon, Bjelosevic, Stefan, Johnstone, Ricky, Webb, Andrew I., Khaw, Seong L., Oshlack, Alicia, Davis, Melissa J., Ekert, Paul G.

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MLL-TFE3: a novel and aggressive KMT2A fusion identified in infant leukemia von Kosasih, Hansen J., Davidson, Nadia M., Bjelosevic, Stefan, Morrish, Emma, Brennan, Margs S., Oshlack, Alicia, Johnstone, Ricky W., Brumatti, Gabriela, Khaw, Seong L., Ekert, Paul G.

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The AKR1C3-Activated Prodrug, Achm-025, Eradicates Disease in Preclinical Models of Aggressive T-Cell Acute Lymphoblastic Leukemia von Lock, Richard B., Toscan, Cara E, McCalmont, Hannah, Evans, Kathryn, Doculara, Louise, Kosasih, Hansen J, Gifford, Andrew J, Ashoorzadeh, Amir, Lin, Xiaojing, Trahair, Toby N, De Bock, Charles E, Patterson, Adam V, Smaill, Jeff B

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In vitro and in vivo modelling of mutant JAK3/STAT5 signaling in leukemia von Omari, Sofia A, Kosasih, Hansen J, Chung, Thomas, de Bock, Charles E

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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma von De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Reunes, Lindy, Kosasih, Hansen J, Reekmans, Alexandra, Brown, Lauren M, Van Roy, Nadine, Palhais, Bruno, Roels, Juliette, Van der Linden, Malaika, Van Dorpe, Jo, Ntziachristos, Panagiotis, Van Delft, Frederik W, Mansour, Marc R, Pieters, Tim, Lammens, Tim, De Moerloose, Barbara, De Bock, Charles E, Goossens, Steven, Van Vlierberghe, Pieter

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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma von De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Reunes, Lindy, Kosasih, Hansen J, Reekmans, Alexandra, Brown, Lauren M, Van Roy, Nadine, Palhais, Bruno, Roels, Juliette, Van der Linden, Malaika, Van Dorpe, Jo, Ntziachristos, Panagiotis, Van Delft, Frederik W, Mansour, Marc R, Pieters, Tim, Lammens, Tim, De Moerloose, Barbara, De Bock, Charles E, Goossens, Steven, Van Vlierberghe, Pieter

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