Into the Eye of the Cytokine Storm von TISONCIK, Jennifer R, KORTH, Marcus J, SIMMONS, Cameron P, FARRAR, Jeremy, MARTIN, Thomas R, KATZE, Michael G

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Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance von Rasmussen, Angela L., Okumura, Atsushi, Ferris, Martin T., Green, Richard, Feldmann, Friederike, Kelly, Sara M., Scott, Dana P., Safronetz, David, Haddock, Elaine, LaCasse, Rachel, Thomas, Matthew J., Sova, Pavel, Carter, Victoria S., Weiss, Jeffrey M., Miller, Darla R., Shaw, Ginger D., Korth, Marcus J., Heise, Mark T., Baric, Ralph S., de Villena, Fernando Pardo-Manuel, Feldmann, Heinz, Katze, Michael G.

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Lassa antiviral LHF-535 protects guinea pigs from lethal challenge von Cashman, Kathleen A., Wilkinson, Eric R., Posakony, Jeffrey, Madu, Ikenna G., Tarcha, Eric J., Lustig, Kurt H., Korth, Marcus J., Bedard, Kristin M., Amberg, Sean M.

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Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes von Cillóniz, Cristian, Shinya, Kyoko, Peng, Xinxia, Korth, Marcus J, Proll, Sean C, Aicher, Lauri D, Carter, Victoria S, Chang, Jean H, Kobasa, Darwyn, Feldmann, Friedericke, Strong, James E, Feldmann, Heinz, Kawaoka, Yoshihiro, Katze, Michael G

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A potent Lassa virus antiviral targets an arenavirus virulence determinant von Madu, Ikenna G, Files, Megan, Gharaibeh, Dima N, Moore, Amy L, Jung, Kie-Hoon, Gowen, Brian B, Dai, Dongcheng, Jones, Kevin F, Tyavanagimatt, Shanthakumar R, Burgeson, James R, Korth, Marcus J, Bedard, Kristin M, Iadonato, Shawn P, Amberg, Sean M

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Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism von Tisoncik-Go, Jennifer, Gasper, David J., Kyle, Jennifer E., Eisfeld, Amie J., Selinger, Christian, Hatta, Masato, Morrison, Juliet, Korth, Marcus J., Zink, Erika M., Kim, Young-Mo, Schepmoes, Athena A., Nicora, Carrie D., Purvine, Samuel O., Weitz, Karl K., Peng, Xinxia, Green, Richard R., Tilton, Susan C., Webb-Robertson, Bobbie-Jo, Waters, Katrina M., Metz, Thomas O., Smith, Richard D., Kawaoka, Yoshihiro, Suresh, M., Josset, Laurence, Katze, Michael G.

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Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling von Peng, Xinxia, Gralinski, Lisa, Armour, Christopher D, Ferris, Martin T, Thomas, Matthew J, Proll, Sean, Bradel-Tretheway, Birgit G, Korth, Marcus J, Castle, John C, Biery, Matthew C, Bouzek, Heather K, Haynor, David R, Frieman, Matthew B, Heise, Mark, Raymond, Christopher K, Baric, Ralph S, Katze, Michael G

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Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection von Cilloniz, Cristian, Pantin-Jackwood, Mary J, Ni, Chester, Goodman, Alan G, Peng, Xinxia, Proll, Sean C, Carter, Victoria S, Rosensweig, Elizabeth R, Szretter, Kristy J, Katz, Jacqueline M, Korth, Marcus J, Swayne, David E, Tumpey, Terrence M, Katze, Michael G

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Pandemic Swine-Origin H1N1 Influenza A Virus Isolates Show Heterogeneous Virulence in Macaques von Safronetz, David, Rockx, Barry, Feldmann, Friederike, Belisle, Sarah E, Palermo, Robert E, Brining, Douglas, Gardner, Don, Proll, Sean C, Marzi, Andrea, Tsuda, Yoshimi, Lacasse, Rachel A, Kercher, Lisa, York, Anthony, Korth, Marcus J, Long, Dan, Rosenke, Rebecca, Shupert, W Lesley, Aranda, Celia Alpuche, Mattoon, John S, Kobasa, Darwyn, Kobinger, Gary, Li, Yan, Taubenberger, Jeffery K, Richt, Jürgen A, Parnell, Michael, Ebihara, Hideki, Kawaoka, Yoshihiro, Katze, Michael G, Feldmann, Heinz

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A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm von Aderem, Alan, Adkins, Joshua N, Ansong, Charles, Galagan, James, Kaiser, Shari, Korth, Marcus J, Law, G Lynn, McDermott, Jason G, Proll, Sean C, Rosenberger, Carrie, Schoolnik, Gary, Katze, Michael G

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Molecular Signatures Associated with Mx1-Mediated Resistance to Highly Pathogenic Influenza Virus Infection: Mechanisms of Survival von CILLONIZ, Cristian, PANTIN-JACKWOOD, Mary J, NI, Chester, CARTER, Victoria S, KORTH, Marcus J, SWAYNE, David E, TUMPEY, Terrence M, KATZE, Michael G

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Genomic Profiling of Tumor Necrosis Factor Alpha (TNF-α) Receptor and Interleukin-1 Receptor Knockout Mice Reveals a Link between TNF-α Signaling and Increased Severity of 1918 Pan... von BELISLE, Sarah E, TISONCIK, Jennifer R, KORTH, Marcus J, CARTER, Victoria S, PROLL, Sean C, SWAYNE, David E, PANTIN-JACKWOOD, Mary, TUMPEY, Terrence M, KATZE, Michael G

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Functional Genomics Reveals the Induction of Inflammatory Response and Metalloproteinase Gene Expression during Lethal Ebola Virus Infection von CILLONIZ, Cristian, EBIHARA, Hideki, NI, Chester, NEUMANN, Gabriele, KORTH, Marcus J, KELLY, Sara M, KAWAOKA, Yoshihiro, FELDMANN, Heinz, KATZE, Michael G

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Systems Virology Identifies a Mitochondrial Fatty Acid Oxidation Enzyme, Dodecenoyl Coenzyme A Delta Isomerase, Required for Hepatitis C Virus Replication and Likely Pathogenesis von RASMUSSEN, Angela L, DIAMOND, Deborah L, SMITH, Richard D, KATZE, Michael G, MCDERMOTT, Jason E, XIAOLI GAO, METZ, Thomas O, MATZKE, Melissa M, CARTER, Victoria S, BELISLE, Sarah E, KORTH, Marcus J, WATERS, Katrina M

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The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways von BILLHARZ, Rosalind, HUI ZENG, KATZE, Michael G, PROLL, Sean C, KORTH, Marcus J, LEDERER, Sharon, ALBRECHT, Randy, GOODMAN, Alan G, ROSENZWEIG, Elizabeth, TUMPEY, Terrence M, GARCIA-SASTRE, Adolfo

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Transcriptomic Analysis Reveals a Mechanism for a Prefibrotic Phenotype in STAT1 Knockout Mice during Severe Acute Respiratory Syndrome Coronavirus Infection von ZORNETZER, Gregory A, FRIEMAN, Matthew B, ROSENZWEIG, Elizabeth, KORTH, Marcus J, PAGE, Carly, BARIC, Ralph S, KATZE, Michael G

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NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways von Tisoncik, Jennifer R, Billharz, Rosalind, Burmakina, Svetlana, Belisle, Sarah E, Proll, Sean C, Korth, Marcus J, Garcíίa-Sastre, Adolfo, Katze, Michael G

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Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection von Peng, Xinxia, Gralinski, Lisa, Ferris, Martin T, Frieman, Matthew B, Thomas, Matthew J, Proll, Sean, Korth, Marcus J, Tisoncik, Jennifer R, Heise, Mark, Luo, Shujun, Schroth, Gary P, Tumpey, Terrence M, Li, Chengjun, Kawaoka, Yoshihiro, Baric, Ralph S, Katze, Michael G

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Hepatitis C virus and liver disease: Global transcriptional profiling and identification of potential markers von Smith, Maria W., Yue, Zhaoxia N., Korth, Marcus J., Do, Hao A., Boix, Loreto, Fausto, Nelson, Bruix, Jordi, Carithers, Robert L., Katze, Michael G.

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The Alpha/Beta Interferon Receptor Provides Protection against Influenza Virus Replication but Is Dispensable for Inflammatory Response Signaling von GOODMAN, Alan G, HUI ZENG, PROLL, Sean C, XINXIA PENG, CILLONIZ, Cristian, CARTER, Victoria S, KORTH, Marcus J, TUMPEY, Terrence M, KATZE, Michael G

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