Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity von Hornung, Michael W, Korte, Joseph J, Olker, Jennifer H, Denny, Jeffrey S, Knutsen, Carsten, Hartig, Phillip C, Cardon, Mary C, Degitz, Sigmund J

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Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases von Olker, Jennifer H, Korte, Joseph J, Denny, Jeffrey S, Hartig, Phillip C, Cardon, Mary C, Knutsen, Carsten N, Kent, Paige M, Christensen, Jessica P, Degitz, Sigmund J, Hornung, Michael W

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In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles von Hornung, Michael W, Kosian, Patricia A, Haselman, Jonathan T, Korte, Joseph J, Challis, Katie, Macherla, Chitralekha, Nevalainen, Erica, Degitz, Sigmund J

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Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase von Olker, Jennifer H., Korte, Joseph J., Haselman, Jonathan T., Hornung, Michael W., Degitz, Sigmund J.

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Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus laevis Using Iopanoic Acid von Haselman, Jonathan T, Olker, Jennifer H, Kosian, Patricia A, Korte, Joseph J, Denny, Jeffrey S, Tietge, Joseph E, Hornung, Michael W, Degitz, Sigmund J

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Targeted Pathway-based In Vivo Testing Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model Amphibian Xenopus laevis von Haselman, Jonathan T, Olker, Jennifer H, Kosian, Patricia A, Korte, Joseph J, Swintek, Joseph A, Denny, Jeffrey S, Nichols, John W, Tietge, Joseph E, Hornung, Michael W, Degitz, Sigmund J

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In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase von Olker, Jennifer H., Korte, Joseph J., Denny, Jeffrey S., Haselman, Jonathan T., Hartig, Phillip C., Cardon, Mary C., Hornung, Michael W., Degitz, Sigmund J.

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Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals von Mayasich, Sally A., Korte, Joseph J., Denny, Jeffrey S., Hartig, Phillip C., Olker, Jennifer H., DeGoey, Philip, O’Flanagan, Joseph, Degitz, Sigmund J., Hornung, Michael W.

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Evaluating Iodide Recycling Inhibition as a Novel Molecular Initiating Event for Thyroid Axis Disruption in Amphibians von Olker, Jennifer H, Haselman, Jonathan T, Kosian, Patricia A, Donnay, Kelby G, Korte, Joseph J, Blanksma, Chad, Hornung, Michael W, Degitz, Sigmund J

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Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis: Manifestations of antiandrogenic and other modes of toxicity von Haselman, Jonathan T., Kosian, Patricia A., Korte, Joseph J., Olmstead, Allen W., Degitz, Sigmund J.

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Development of the Larval Amphibian Growth and Development Assay: effects of chronic 4-tert-octylphenol or 17β-trenbolone exposure in Xenopus laevis from embryo to juvenile von Haselman, Jonathan T., Kosian, Patricia A., Korte, Joseph J., Olmstead, Allen W., Iguchi, Taisen, Johnson, Rodney D., Degitz, Sigmund J.

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Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas) von Ankley, Gerald T., Jensen, Kathleen M., Kahl, Michael D., Korte, Joseph J., Makynen, Elizabeth A.

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Progress towards Development of an Amphibian-Based Thyroid Screening Assay Using Xenopus laevis. Organismal and Thyroidal Responses to the Model Compounds 6-Propylthiouracil, Methi... von Degitz, Sigmund J., Holcombe, Gary W., Flynn, Kevin M., Kosian, Patricia A., Korte, Joseph J., Tietge, Joseph E.

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Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole von Tietge, Joseph E., Degitz, Sigmund J., Haselman, Jonathan T., Butterworth, Brian C., Korte, Joseph J., Kosian, Patricia A., Lindberg-Livingston, Annelie J., Burgess, Emily M., Blackshear, Pamela E., Hornung, Michael W.

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Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis von Tietge, Joseph E., Butterworth, Brian C., Haselman, Jonathan T., Holcombe, Gary W., Hornung, Michael W., Korte, Joseph J., Kosian, Patricia A., Wolfe, Marilyn, Degitz, Sigmund J.

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Evaluation of the Aromatase Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas) von Ankley, Gerald T., Kahl, Michael D., Jensen, Kathleen M., Hornung, Michael W., Korte, Joseph J., Makynen, Elizabeth A., Leino, Richard L.

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Effects of the androgenic growth promoter 17-β-trenbolone on fecundity and reproductive endocrinology of the fathead minnow von Ankley, Gerald T., Jensen, Kathleen M., Makynen, Elizabeth A., Kahl, Michael D., Korte, Joseph J., Hornung, Michael W., Henry, Tala R., Denny, Jeffrey S., Leino, Richard L., Wilson, Vickie S., Cardon, Mary C., Hartig, Phillip C., Gray, L. Earl

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Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile von Haselman, Jonathan T., Sakurai, Maki, Watanabe, Naoko, Goto, Yasushi, Onishi, Yuta, Ito, Yuki, Onoda, Yu, Kosian, Patricia A., Korte, Joseph J., Johnson, Rodney D., Iguchi, Taisen, Degitz, Sigmund J.

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Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor von Olmstead, Allen W., Kosian, Patricia A., Korte, Joseph J., Holcombe, Gary W., Woodis, Kacie K., Degitz, Sigmund J.

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Metamorphic inhibition of Xenopus laevis by sodium perchlorate: Effects on development and thyroid histology von Tietge, Joseph E., Holcombe, Gary W., Flynn, Kevin M., Kosian, Patricia A., Korte, Joseph J., Anderson, Leroy E., Wolf, Douglas C., Degitz, Sigmund J.

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