A novel bispecific antibody for EGFR-directed blockade of the PD-1/PD-L1 immune checkpoint von Koopmans, Iris, Hendriks, Djoke, Samplonius, Douwe F., van Ginkel, Robert J., Heskamp, Sandra, Wierstra, Peter J., Bremer, Edwin, Helfrich, Wijnand

Volltext

Bispecific antibody approach for EGFR-directed blockade of the CD47-SIRPα "don't eat me" immune checkpoint promotes neutrophil-mediated trogoptosis and enhances antigen cross-prese... von Hendriks, Mark A. J. M., Ploeg, Emily M., Koopmans, Iris, Britsch, Isabel, Ke, Xiurong, Samplonius, Douwe F., Helfrich, Wijnand

Volltext

CSPG4: A Target for Selective Delivery of Human Cytolytic Fusion Proteins and TRAIL von Jordaan, Sandra, Chetty, Shivan, Mungra, Neelakshi, Koopmans, Iris, van Bommel, Peter E, Helfrich, Wijnand, Barth, Stefan

Volltext

Bispecific Antibody Approach for Improved Melanoma-Selective PD-L1 Immune Checkpoint Blockade von Koopmans, Iris, Hendriks, Mark A.J.M., van Ginkel, Robert J., Samplonius, Douwe F., Bremer, Edwin, Helfrich, Wijnand

Volltext

Abstract 4553: A novel bispecific antibody for EGFR-directed blockade of the PD-1/PD-L1 immune checkpoint von Koopmans, Iris, Samplonius, Douwe F., Ginkel, Robert J. van, Wierstra, Peter J., Heskamp, Sandra, Bremer, Edwin, Helfrich, Wijnand

Volltext

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins von van Andel, Harmen, Ren, Zemin, Koopmans, Iris, Joosten, Sander P. J., Kocemba, Kinga A., de Lau, Wim, Kersten, Marie José, de Bruin, Alexander M., Guikema, Jeroen E. J., Clevers, Hans, Spaargaren, Marcel, Pals, Steven T.

Volltext

Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction von Hendriks, Djoke, He, Yuan, Koopmans, Iris, Wiersma, Valerie R., van Ginkel, Robert J., Samplonius, Douwe F., Helfrich, Wijnand, Bremer, Edwin

Volltext

Incidence and management of toxicity associated with ibrutinib and idelalisib: a practical approach von de Weerdt, Iris, Koopmans, Suzanne M, Kater, Arnon P, van Gelder, Michel

Volltext

A smartphone- and wearable-based biomarker for the estimation of unipolar depression severity von Zhuparris, Ahnjili, Maleki, Ghobad, van Londen, Liesbeth, Koopmans, Ingrid, Aalten, Vincent, Yocarini, Iris E., Exadaktylos, Vasileios, van Hemert, Albert, Cohen, Adam, Gal, Pim, Doll, Robert-Jan, Groeneveld, Geert Jan, Jacobs, Gabriël, Kraaij, Wessel

Volltext

Early Measles Vaccination During an Outbreak in the Netherlands: Short-Term and Long-Term Decreases in Antibody Responses Among Children Vaccinated Before 12 Months of Age von Brinkman, Iris D, de Wit, Jelle, Smits, Gaby P, Ten Hulscher, Hinke I, Jongerius, Maria C, Abreu, Taymara C, van der Klis, Fiona R M, Hahné, Susan J M, Koopmans, Marion P G, Rots, Nynke Y, van Baarle, Debbie, van Binnendijk, Robert S

Volltext

Association of Objectively Measured Sedentary Behavior With Arterial Stiffness: Findings From the Nijmegen Exercise Study von Sluijs, Koen M., Bakker, Esmée A., Kerstens, Thijs P., Stens, Niels A., Koning, Iris A., Thannhauser, Jos, Malik, Afrah E. F., Reesink, Koen D., Nabeel, P. M., Raj, Kiran V., Joseph, Jayaraj, Allard, Neeltje A.E., Berge, Kristian, Bongers, Coen C.W.G., Brouwer, Calvin G., Hartman, Yvonne A.W., Hazeleger, Lotte R., Hopman, Maria T.E., Janssen, Sylvan L.J.E., Janssen Daalen, Jules M., Kersten, Bregina T.P., Koopmans, Lotte, Kroesen, Sophie H., Landman, Thijs R.J., Luiken, Tom T.J., Mast, Isa H., Peggen, Mandy A.G., Schoofs, Merle C.A., Schreurs, Bibi A., Vermeulen, Jenske J.M., Vloet, Janneke I.A., Wanders, Lisa, Eijsvogels, Thijs M. H., Thijssen, Dick H. J.

Volltext

Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration von Nguyen, Phong D, Gooijers, Iris, Campostrini, Giulia, Verkerk, Arie O, Honkoop, Hessel, Bouwman, Mara, de Bakker, Dennis E M, Koopmans, Tim, Vink, Aryan, Lamers, Gerda E M, Shakked, Avraham, Mars, Jonas, Mulder, Aat A, Chocron, Sonja, Bartscherer, Kerstin, Tzahor, Eldad, Mummery, Christine L, de Boer, Teun P, Bellin, Milena, Bakkers, Jeroen

Volltext

The INTOXICATE study: methodology and preliminary results of a prospective observational study von Zwaag, Samanta M, van den Hengel-Koot, Irma S, Baker, Stuart, Druwé, Patrick, Elhadi, Muhammed, Dufol, Ana Ferrer, Forsberg, Sune, Halacli, Burcin, Jung, Christian, Laubner Sakalauskienė, Gabija, Lindqvist, Elin, Moreno, Rui, Rabe, Christian, Reiter, Nanna, Rezar, Richard, Țincu, Radu, Topeli, Arzu, Wood, David M, de Lange, Dylan W, Hunault, Claudine C

Volltext

Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Stu... von Van Bockstal, Mieke R., Cooks, Maxine, Nederlof, Iris, Brinkhuis, Mariel, Dutman, Annemiek, Koopmans, Monique, Kooreman, Loes, van der Vegt, Bert, Verhoog, Leon, Vreuls, Celine, Westenend, Pieter, Kok, Marleen, van Diest, Paul J., Nauwelaers, Inne, Laudus, Nele, Denkert, Carsten, Rimm, David, Siziopikou, Kalliopi P., Ely, Scott, Zardavas, Dimitrios, Roberts, Mustimbo, Floris, Giuseppe, Hartman, Johan, Acs, Balazs, Peeters, Dieter, Bartlett, John M. S., Dequeker, Els, Salgado, Roberto, Giudici, Fabiola, Michiels, Stefan, Horlings, Hugo, van Deurzen, Carolien H. M.

Volltext

Early Measles Vaccination During an Outbreak in the Netherlands: Short-Term and Long-Term Decreases in Antibody Responses Among Children Vaccinated Before 12 Months of Age von Brinkman, Iris D, de Wit, Jelle, Smits, Gaby P, Ten Hulscher, Hinke I, Jongerius, Maria C, Abreu, Taymara C, van der Klis, Fiona R.M, Hahné, Susan J.M, Koopmans, Marion P.G, Rots, Nynke Y, van Baarle, Debbie, van Binnendijk, Robert S

Volltext

Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endo... von Laan, Sebastiaan N.J., de Boer, Suzan, Dirven, Richard J., van Moort, Iris, Kuipers, Thomas B., Mei, Hailiang, Bierings, Ruben, Eikenboom, Jeroen, Brands, Martijn, Koopman, Sjoerd, Bukkems, Laura, Cloesmeijer, Michael, Janssen, Alexander, Fijnvandraat, Karin, Gouw, Samantha, Mathôt, Ron, Haverman, Lotte, van den Akker, Emile, van den Biggelaar, Maartje, de Haas, Masja, Meijer, Sander, Voorberg, Jan, Del Castillo Alferez, Jessica, Zhang, Huan, Boender, Johan, Meijer, Stephan, Meijer, Karina, de Jong, Sean, Goedhart, Geertje, van der Bom, Anske, Bos, Mettine, Eikenboom, Jeroen, van der Meer, Felix, Laan, Sebastiaan, Schols, Saskia, Bierings, Ruben, Burdorf, Lex, Cnossen, Marjon, Hazelzet, Jan, Huisman, Elise, Kruip, Marieke, Leebeek, Frank, van Leeuwen, Nikki, Lingsma, Hester, de Maat, Moniek, van Moort, Iris, Polinder, Suzanne, Reitsma, Simone, Roest, Eliza, Arisz, Ryanne, Romano, Lorenzo, Al Arashi, Wala, van Hoorn, Shannon, Goedhart, Tine, Mussert, Caroline, Prameyllawati, Diaz, Uyl, Carin, Jansen, Nathalie, Fischer, Kathelijn, Ploos van Amstel, Hans Kristian, Urbanus, Rolf, Zivkovic, Minka, Bredenoord, Annelien, van der Graaf, Rieke, Baas, Lieke, Schutgens, Roger, Driessens, Mariëtte

Volltext

Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Stu... von Van Bockstal, Mieke R, Cooks, Maxine, Nederlof, Iris, Brinkhuis, Mariel, Dutman, Annemiek, Koopmans, Monique, Kooreman, Loes, van der Vegt, Bert, Verhoog, Leon, Vreuls, Celine, Westenend, Pieter, Kok, Marleen, van Diest, Paul J, Nauwelaers, Inne, Laudus, Nele, Denkert, Carsten, Rimm, David, Siziopikou, Kalliopi P, Ely, Scott, Zardavas, Dimitrios, Roberts, Mustimbo, Floris, Giuseppe, Hartman, Johan, Acs, Balazs, Peeters, Dieter, Bartlett, John M. S, Dequeker, Els, Salgado, Roberto, Giudici, Fabiola, Michiels, Stefan, Horlings, Hugo, van Deurzen, Carolien H. M

Volltext

Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Stu... von Van Bockstal, Mieke R, Cooks, Maxine, Nederlof, Iris, Brinkhuis, Mariel, Dutman, Annemiek, Koopmans, Monique, Kooreman, Loes, van der Vegt, Bert, Verhoog, Leon, Vreuls, Celine, Westenend, Pieter, Kok, Marleen, van Diest, Paul J, Nauwelaers, Inne, Laudus, Nele, Denkert, Carsten, Rimm, David, Siziopikou, Kalliopi P, Ely, Scott, Zardavas, Dimitrios, Roberts, Mustimbo, Floris, Giuseppe, Hartman, Johan, Acs, Balazs, Peeters, Dieter, Bartlett, John M.S, Dequeker, Els, Salgado, Roberto, Giudici, Fabiola, Michiels, Stefan, Horlings, Hugo, van Deurzen, Carolien H.M

Volltext

Hesperos: A geophysical mission to Venus von Koopmans, Robert-Jan, Białek, Agata, Donohoe, Anthony, Jiménez, María Fernández, Frasl, Barbara, Gurciullo, Antonio, Kleinschneider, Andreas, Łosiak, Anna, Mannel, Thurid, Elorza, Iñigo Muñoz, Nilsson, Daniel, Oliveira, Marta, Sørensen-Clark, Paul Magnus, Timoney, Ryan, van Zelst, Iris

Volltext bestellen

Hesperos: A geophysical mission to Venus von Robert-Jan Koopmans, Białek, Agata, Donohoe, Anthony, María Fernández Jiménez, Frasl, Barbara, Gurciullo, Antonio, Kleinschneider, Andreas, Łosiak, Anna, Mannel, Thurid, Iñigo Muñoz Elorza, Nilsson, Daniel, Oliveira, Marta, Sørensen-Clark, Paul Magnus, Timoney, Ryan, Iris van Zelst

Volltext